Emergence in Japan of an imipenem-susceptible, meropenem-resistant Klebsiella pneumoniae carrying bla IMP-6

Diagnostic Microbiology and Infectious Disease

Volumn 72, Issue 1, 2012, Pages 109-112

  Shigemoto, Norifumi ^a,b   Kuwahara, Ryuichi ^a,b   Kayama, Shizuo ^a,b   Shimizu, Wataru ^a,b   Onodera, Makoto ^a,c   Yokozaki, Michiya ^a,c   Hisatsune, Junzo ^a,b   Kato, Fuminori ^a,b   Ohge, Hiroki ^a,d   Sugai, Motoyuki ^a,b  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

^d Division of Infectious Diseases   (Japan)

Author keywords

Carbapenem resistance; ESBL; Klebsiella; Metallo lactamase

Indexed keywords

AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; AZTREONAM; BIAPENEM; CEFACLOR; CEFAZOLIN; CEFMETAZOLE; CEFOTAXIME; CEFOTIAM; CEFOZOPRAN; CEFPIROME; CEFPODOXIME; CEFTAZIDIME; CHLORAMPHENICOL; CIPROFLOXACIN; COTRIMOXAZOLE; DORIPENEM; FLOMOXEF; FOSFOMYCIN; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; MINOCYCLINE; PANIPENEM; PIPERACILLIN; SULPERAZON;

AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; BLACTXM2 GENE; BLAIMP6 GENE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; IMIPENEM SUSCEPTIBLE BUT MEROPENEM RESISTANT KLEBSIELLA; JAPAN; KLEBSIELLA; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; MALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL;

AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CONJUGATION, GENETIC; FEMALE; GENE TRANSFER, HORIZONTAL; HUMANS; IMIPENEM; JAPAN; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; PLASMIDS; THIENAMYCINS;

EID: 83055176346     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2011.09.019     Document Type: Article

References (9)

1. Clinical and Laboratory Standards Institute Performance standards for antimicrobial susceptibility testing; 20th informational supplement. M100-S20 2010, CLSI, Wayne, PA.
2. Diancourt L., Passet V., Verhoef J., Grimont P.A.D., Brisse S. Multilocus sequence typing of Klebsiella pneumoniae nosocomial islates. J. Clin. Microbiol. 2005, 43:4178-4182.
3. Genthner F.J., Chatterjee P., Barkay T., Bourquin A.W. Capacity of aquatic bacteria to act as recipients of plasmid DNA. Appl. Environ. Microbiol. 1988, 54:115-117.
4. Kasuga K., Matsumoto T., Kanai S., Oana K., Honda T., Kawakami Y. Successful isolation of IMP-1 carbapenemase-producing but not carbapenem-resistant species in Enterobacteriaceae family. Jpn. J. Infect. Dis. 2010, 84:569-574.
5. Koh T.H., Sng L.H., Babini G.S., Woodford N., Livermore D.M., Hall L.M.C. Carbapenem-resistant Klebsiella pneumoniae in Singapore producing IMP-1 β-lactamase and lacking an outer membrane protein. Antimicrob. Agents Chemother. 2001, 45:1939-1940.
6. IMP-1 gene cassette in Hiroshima. J. Antimicrob. Chemother. 2009, 64:46-51.
7. CTX-M genes and the qnr determinant in Enterobacter cloacae, Klebsiella pneumoniae and Klebsiella oxytoca isolates. J. Antimicrob. Chemother. 2010, 65:661-665.
8. Shibata N., Kurokawa H., Doi Y., Yagi T., Yamane K., Wachino J., et al. PCR classification of CTX-M-type beta-lactamase genes identified in clinically isolated Gram-negative bacilli in Japan. Antimicrob. Agents Chemother. 2006, 50:791-795.
9. Yano H., Kuga A., Okamoto R., Kitasato H., Kobayashi T., Inoue M. Plasmid-encoded metallo-β-lactamase (IMP-6) conferring resistance to carbapenems, especially meropenem. Antimicrob. Agents Chemother. 2001, 45:1343-1348.