Delivery of sesamol-loaded solid lipid nanoparticles to the brain for menopause-related emotional and cognitive central nervous system derangements

Rejuvenation Research

Volumn 14, Issue 6, 2011, Pages 597-604

  Kakkar, Vandita ^a   Mishra, Anil Kumar ^b   Chuttani, Krishna ^b   Chopra, Kanwaljit ^a   Kaur, Indu Pal ^a  

^a PANJAB UNIVERSITY   (India)

^b INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CENTRAL NERVOUS SYSTEM AGENTS; PHOSPHATIDYLCHOLINE; SESAMOL; SOLID LIPID NANOPARTICLE; UNCLASSIFIED DRUG;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; CENTRAL NERVOUS SYSTEM; COGNITIVE DEFECT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; EMOTIONAL DISORDER; FEMALE; MENOPAUSE RELATED DISORDER; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RABBIT; RAT; SCINTIGRAPHY;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; BENZODIOXOLES; BRAIN; CENTRAL NERVOUS SYSTEM; COGNITION; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EMOTIONS; FEMALE; FLUORESCENT DYES; GLUTATHIONE; MENOPAUSE; MICROSCOPY, CONFOCAL; NANOPARTICLES; OXIDATIVE STRESS; PHENOLS; PHOSPHATIDYLCHOLINES; RATS; RATS, WISTAR; SOLUBILITY; SUPEROXIDE DISMUTASE; SURFACE-ACTIVE AGENTS; TECHNOLOGY, PHARMACEUTICAL;

EID: 83755225768     PISSN: 15491684     EISSN: 15578577     Source Type: Journal    
DOI: 10.1089/rej.2011.1193     Document Type: Article

References (38)

1. Namiki M. The chemistry and physiological functions of sesame. Food Rev Int 1995;11:281-329.
2. Wu WH, Kang YP, Wang NH, Jou HJ, Wang TA. Sesame ingestion affects sex hormones, antioxidant status, and blood lipids in postmenopausal women. J Nutr 2006;1365: 1270-1275.
3. Joseá LP, Heinonen SM, Aura AM, Adlercreutz H. Dietary sesamin is converted to enterolactone in humans. J Nutr 2005;135:1056-1062. (Pubitemid 40645290)
4. Thiraviam G, Bhandari R, Kaur IP. Sesamol: An efficient antioxidant with potential therapeutic benefits. Med Chem 2009;5:367-371.
5. Sharma S, Kaur IP. Development and evaluation of sesamol as an antiaging agent. Int J Dermatol 2006;45:200-208. (Pubitemid 43337630)
6. Kaur IP, Saini A. Sesamol exhibits antimutagenic activity against oxygen species mediated mutagenicity. Mutat Res 2000;470:71-74.
7. Kapadia GJ, Azuine MA, Tokuda H, Takasaki M, Mukainaka T, Konoshima T, Nishino H. Chemopreventive effect of resveratrol, sesamol, sesame oil and sunflower oil in Epstein-Barr virus early antigen activation assay and the mouse skin two-stage carcinogenesis. Pharmacol Res 2002;45:499-505. (Pubitemid 35304500)
8. Vennila L, Pugalendi KV. Protective effect of sesamol against myocardial infarction caused by isoproterenol in Wistar rats. Redox Rep 2010;15:36-42.
9. VanGilder RL, Kelly KA, Chua MD, Ptachcinski RL, Huber JD. Administration of sesamol improved blood-brain barrier function in streptozotocin induced diabetic rats. Exp Brain Res 2009;197:23-34.
10. Kumar P, Kalonia H, Kumar A. Sesamol attenuate 3-nitropropionic acid-induced Huntington-like behavioral, biochemical, and cellular alterations in rats. J Asian Nat Prod Res 2009;11:439-450.
11. Wenzel E, Soldo T, Erbersdobler H, Somoza V. Bioactivity and metabolism of trans-resveratrol orally administered to Wistar rats. Mol Nutr Food Res 2005;49:482-494. (Pubitemid 40780395)
12. Jan KC, Ho CT, Hwang LS. Bioavailability and tissue distribution of sesamol in rat. J Agric Food Chem 2008;56: 7032-7037.
13. Jan KC, Ho CT, Hwang LS. Elimination and metabolism of sesamol, a bioactive compound in sesame oil, in rats. Mol Nutr Food Res 2009;53:36-43.
14. Oyewumi MO, Yokel RA, Jay M, Coakley T, Mumper RJ. Comparison of cell uptake, biodistribution and tumor retention of folate coated and PEG coated gadolinium nanoparticles in tumor bearing mice. J Control Release 2004;95: 613-626. (Pubitemid 38340510)
15. Manjunath K, Reddy JS, Venkateswarlu V. Solid lipid nanoparticles as drug delivery systems. Methods Find Exp Clin Pharmacol 2005;27:127.
16. Lister RG. The use of a plus maze to measure anxiety in the mouse. Psychopharmacology 1987;92:180-185. (Pubitemid 17072893)
17. Thompson HJ, LeBold DG, Marklund N, Morales DM, Hagner AP, Mclntosh TK. Cognitive evaluation of traumatically brain-injured rats using serial testing in the Morris water maze. Restor Neurol Neurosc 2006;24:109-114. (Pubitemid 43742584)
18. Layne E. Spectrophotometric and turbidimetric methods for measuring proteins. Methods Enzymol 1957;10:447-455.
19. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-358. (Pubitemid 9194347)
20. Ellman GL. Tissue sulfhdryl groups. Arch Biochem Biophy 1959;82:70-77.
21. Kono Y. Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. Arch Biochem Biophys 1978;186:189-195. (Pubitemid 8290500)
22. Eckelman WC. Radiolabeling with technetium-99m to study high-capacity and low-capacity biochemical systems. Eur J Nucl Med 1995;22:249-263.
23. Jha SK, Dougall P, Behari M, Ahuja GK. Interictal brain 99mTc-HMPAO SPECT study in chronic epilepsy. J Assoc Physicians India 1998;46:438-441. (Pubitemid 128523772)
24. Babbar AK, Singh AK, Goel HC, Chauhan UPS, Sharma RK. Evaluation of 99mTc-labeled Photosan-3, a hematoporphyrin derivative, as a potential radiopharmaceutical for tumor scintigraphy. Nucl Med Biol 2000;27:419-426. (Pubitemid 30639060)
25. Saha GB. Methods of radiolabeling. In: Physics and Radiobiology of Nuclear Medicine. Springer-Verlag, New York, 2006, pp.100-106.
26. Gasco MR. 1993. US patent 5250236.
27. Cavelli R, Marengo E, Rodriguez L, Gasco MR. Effects of some experimental factors on the production process of solid lipid nanoparticles. Eur J Pharm Biopharm 1996;42: 110-115. (Pubitemid 26173946)
28. Kaur IP, Bhandari R, Bhandari S, Kakkar V. Potential of solid lipid nanoparticles for brain targeting. J Control Release 2008;127:97-109.
29. Zur Muhlen A, Schwarz C, Mehnert W. Solid lipid nanoparticles (SLN) for controlled drug delivery-Drug release and release mechanisms. Eur J Pharm Biopharm 1998;45: 149-155. (Pubitemid 28167741)
30. Reddy JS, Venkateshwarlu V. Novel delivery systems for drug targeting to the brain. Drugs of the Future 2004;29:63-83.
31. Vural P, Akgul C, Canbaz M. Effects of menopause and tibolone on antioxidants in postmenopausal women. Ann Clin Biochem 2005;42:220-223. (Pubitemid 40694963)
32. Polisseni AF, Araujo DA, Polisseni F, Mourao Junior CA, Polisseni J, Fernandes ES, Guerra MO. Depression and anxiety in menopausal women: Associated factors. Rev Bras Ginecol Obstet 2009;31:117-123.
33. Betti S, Orsini MR, Sciaky R, Cristini C, Cesa-Bianchi G, Zandonini GF. Attitudes towards menopause in a group of women followed in a public service for menopause counseling. Aging (Milano) 2001;13:331-381.
34. Geetha T, Rohit B, Pal KI. Sesamol: An efficient antioxidant with potential therapeutic benefits.MedChem2009;5:367-371.
35. Prasad NR, Mahesh T, Menon VP, Jeevanram RK, Pugalendi KV. Photoprotective effect of sesamol on UVB-radiation induced oxidative stress in human blood lymphocytes in vitro. Environ Toxicol Pharmacol 2005;20:1-5. (Pubitemid 40615349)
36. Joshi R, Kumar MS, Satyamoorthy K, Unnikrisnan MK, Mukherjee T. Free radical reactions and antioxidant activities of sesamol: Pulse radiolytic and biochemical studies. J Agric Food Chem 2005;53:2696-2703. (Pubitemid 40471753)
37. Hirose N, Inoue T, Nishihara K, Sugano M, Akimoto K, Shimizu S, Yamada H. Inhibition of cholesterol absorption and synthesis in rats by sesamin. J Lipid Res 1991;37:218-224.
38. Pallardoá FV, Asensi M, Garc?áa de la Asuncion J, Antoán V, Lloret A, Sastre J, Vinoe a J. Late onset administration of oral antioxidants prevents age-related loss of motor co-ordination and brain mitochondrial DNA damage. Free Radical Res 1998;29:617-623. (Pubitemid 29112732)