Baicalein suppresses the SOS response system of Staphylococcus aureus induced by ciprofloxacin

Cellular Physiology and Biochemistry

Volumn 28, Issue 5, 2011, Pages 1045-1050

  Peng, Qing ^a   Zhou, Shuqin ^b   Yao, Fen ^a   Hou, Bing ^c   Huang, Yuanchun ^a   Hua, Dexing ^d   Zheng, Yanshan ^a   Qian, Yuanshu ^a  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c Clinical Laboratory of Dermatosis Hospital   (China)

^d Clinical Laboratory of Yuebei Hospital   (China)

Author keywords

Bacailein; Ciprofloxacin; SOS response; Staphylococcus aureus

Indexed keywords

ADENOSINE TRIPHOSPHATE; BAICALEIN; CIPROFLOXACIN; LEXA PROTEIN; REACTIVE OXYGEN METABOLITE; RIFAMPICIN; SOS PROTEIN;

ARTICLE; BACTERIAL MUTATION; CONTROLLED STUDY; DNA REPAIR; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; RECA GENE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION;

EID: 83755207539     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000335791     Document Type: Article

References (22)

1. Ysern P, Clerch B, Castano M, Gibert I, Barbe J, Llagostera M: Induction of sos genes in escherichia coli and mutagenesis in salmonella typhimurium by fluoroquinolones. Mutagenesis 1990;5:63-66. (Pubitemid 20102071)
2. Varhimo E, Savijoki K, Jefremoff H, Jalava J, Sukura A, Varmanen P: Ciprofloxacin induces mutagenesis to antibiotic resistance independent of umuc in streptococcus uberis. Environ Microbiol 2008;10:2179-2183.
3. Cirz RT, Chin JK, Andes DR, de Crecy-Lagard V, Craig WA, Romesberg FE: Inhibition of mutation and combating the evolution of antibiotic resistance. PLoS Biol 2005;3:e176.
4. Shaw KJ, Miller N, Liu X, Lerner D, Wan J, Bittner A, Morrow BJ: Comparison of the changes in global gene expression of escherichia coli induced by four bactericidal agents. J Mol Microbiol Biotechnol 2003;5:105-122. (Pubitemid 37475754)
5. Baharoglu Z, Mazel D: Vibrio cholerae triggers sos and mutagenesis in response to a wide range of antibiotics: A route towards multiresistance. Antimicrob Agents Chemother; 2011;55:2438-2441.
6. Miller C, Thomsen LE, Gaggero C, Mosseri R, Ingmer H, Cohen SN: Sos response induction by beta-lactams and bacterial defense against antibiotic lethality. Science 2004;305:1629-1631. (Pubitemid 39296359)
7. Urios A, Herrera G, Aleixandre V, Blanco M: Influence of reca mutations on gyra dependent quinolone resistance. Biochimie 1991;73:519-521.
8. Dwyer DJ, Kohanski MA, Collins JJ: Role of reactive oxygen species in antibiotic action and resistance. Curr Opin Microbiol 2009;12:482-489.
9. Kohanski MA, DePristo MA, Collins JJ: Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis. Mol Cell 2010;37:311-320.
10. Kohanski MA, Dwyer DJ, Wierzbowski J, Cottarel G, Collins JJ: Mistranslation of membrane proteins and twocomponent system activation trigger antibiotic-mediated cell death. Cell 2008;135:679-690.
11. Renzette N, Sandler SJ: Requirements for atp binding and hydrolysis in reca function in escherichia coli. Mol Microbiol 2008;67:1347-1359. (Pubitemid 351316960)
12. Gruenig MC, Renzette N, Long E, Chitteni-Pattu S, Inman RB, Cox MM, Sandler SJ: Reca-mediated sos induction requires an extended filament conformation but no atp hydrolysis. Mol Microbiol 2008;69:1165-1179.
13. Fujita M, Shiota S, Kuroda T, Hatano T, Yoshida T, Mizushima T, Tsuchiya T: Remarkable synergies between baicalein and tetracycline, and baicalein and betalactams against methicillin-resistant staphylococcus aureus. Microbiol Immunol 2005;49:391-396. (Pubitemid 40628500)
14. Perez CA, Wei Y, Guo M: Iron-binding and anti-fenton properties of baicalein and baicalin. J Inorg Biochem 2009;103:326-332.
15. Chinnam N, Dadi PK, Sabri SA, Ahmad M, Kabir MA, Ahmad Z: Dietary bioflavonoids inhibit escherichia coli atp synthase in a differential manner. Int J Biol Macromol 2010;46:478-486.
16. Cirz RT, Jones MB, Gingles NA, Minogue TD, Jarrahi B, Peterson SN, Romesberg FE: Complete and sos-mediated response of staphylococcus aureus to the antibiotic ciprofloxacin. J Bacteriol 2007;189:531-539. (Pubitemid 46106385)
17. Rosche WA, Foster PL: Determining mutation rates in bacterial populations. Methods 2000;20:4-17. (Pubitemid 30119596)
18. Hall BM, Ma CX, Liang P, Singh KK: Fluctuation analysis calculator: A web tool for the determination of mutation rate using luria-delbruck fluctuation analysis. Bioinformatics 2009;25:1564-1565.
19. Kohanski MA, Dwyer DJ, Hayete B, Lawrence CA, Collins JJ: A common mechanism of cellular death induced by bactericidal antibiotics. Cell 2007;130:797-810. (Pubitemid 47332566)
20. Egelman EH, Stasiak A: Electron microscopy of reca-DNA complexes: Two different states, their functional significance and relation to the solved crystal structure Micron 1993;24:309-324.
21. Yu X, Egelman EH: Structural data suggest that the active and inactive forms of the reca filament are not simply interconvertible. J Mol Biol 1992;227:334-346.
22. Zhang XP, Cheng QH, Chen JF, Mao JB, Lu B, JU TF: Acute toxicity test of baicalein capsule in mice. J Med Res 2007;36:52-55.