Shear stress reverses dome formation in confluent renal tubular cells

Cellular Physiology and Biochemistry

Volumn 28, Issue 4, 2011, Pages 673-682

  Cattaneo, Irene ^a   Condorelli, Lucia ^a   Terrinoni, Anna R ^b   Antiga, Luca ^a   Sangalli, Fabio ^a   Remuzzi, Andrea ^a,c  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b Centro COGES   (Italy)

^c UNIVERSITY OF BERGAMO   (Italy)

Author keywords

Cilia; Cytoskeleton; MDCK; Shear stress; ZO 1

Indexed keywords

ACTIN; CALCIUM ION; EGTAZIC ACID; PROTEIN ZO1;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL DOME; CELL STRAIN; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; KIDNEY TUBULE CELL; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SHEAR STRESS; STRESS FIBER; VIDEORECORDING;

EID: 83755195387     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000335813     Document Type: Article

References (39)

1. Latta H, Maunsbach AB, Madden SC: Cilia in different segments of the rat nephron. J Biophys Biochem Cytol 1961;11:248-252.
2. Nauli SM, Alenghat FJ, Luo Y, Williams E, Vassilev P, Li X, Elia AE, Lu W, Brown EM, Quinn SJ, Ingber DE, Zhou J: Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet 2003;33:129-137. (Pubitemid 36177063)
3. Praetorius HA, Spring KR: Bending the MDCK cell primary cilium increases intracellular calcium. J Membr Biol 2001;184:71-79. (Pubitemid 33016173)
4. Praetorius HA, Spring KR: The renal cell primary cilium functions as a flow sensor. Curr Opin Nephrol Hypertens 2003;12:517-520. (Pubitemid 37083112)
5. Praetorius HA, Spring KR: Removal of the MDCK cell primary cilium abolishes flow sensing. J Membr Biol 2003;191:69-76. (Pubitemid 37011467)
6. Borkan SC, Wang YH, Lieberthal W, Burke PR, Schwartz JH: Heat stress ameliorates ATP depletion-induced sublethal injury in mouse proximal tubule cells. Am J Physiol 1997;272:F347-355.
7. Rydholm S, Zwartz G, Kowalewski JM, Kamali-Zare P, Frisk T, Brismar H Mechanical Properties of Primary Cilia Regulate the Response to Fluid Flow Am J Physiol Renal Physiol 2010; in press.
8. Siroky BJ, Ferguson WB, Fuson AL, Xie Y, Fintha A, Komlosi P, Yoder BK, Schwiebert EM, Guay-Woodford LM, Bell PD: Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells. Am J Physiol Renal Physiol 2006;290:F1320-1328. (Pubitemid 43830756)
9. Hansson GC, Simons K, van Meer G: Two strains of the Madin-Darby canine kidney (MDCK) cell line have distinct glycosphingolipid compositions. EMBO J 1986;5:483-489.
10. Lever JE: Regulation of dome formation in kidney epithelial cell cultures. Ann N Y Acad Sci 1981;372:371-383. (Pubitemid 12175076)
11. Chang YH, Lin HH, Wang YK, Chiu WT, Su HW, Tang MJ: Activation of caspase-8 and Erk-1/2 in domes regulates cell death induced by confluence in MDCK cells. J Cell Physiol 2007;211:174-182.
12. Bukanov O. N. HH, Dackowski WR, Lawrence BD, Clow PA, Roberts BL, Klinger KW, Ibraghimov-Beskrovnaya O: Functional polycystin-1 expression is developmentally regulated during epithelial morphogenesis in vitro: downregulation and loss of membrane localization during cystogenesis. Human Molecular Genetics 2002;11:923-936. (Pubitemid 34449780)
13. Overgaard KMS, Krystle S. Spiczka, Sheff DR, Alexander S, Yeaman C: Deciliation is associated with dramatic remodeling of epithelial cell junctions and surface domains. Mol Biol Cell 2009;20:102-113.
14. Kotsis F, Nitschke R, Doerken M, Walz G, Kuehn EW: Flow modulates centriole movements in tubular epithelial cells. Pflugers Arch 2008;456:1025-1035.
15. Rydholm S, Frisk T, Kowalewski JM, Andersson Svahn H, Stemme G, Brismar H: Microfluidic devices for studies of primary cilium mediated cellular response to dynamic flow conditions. Biomed Microdevices 2008;10:555-560.
16. Morigi M, Zoja C, Figliuzzi M, Foppolo M, Micheletti G, Bontempelli M, Saronni M, Remuzzi G, Remuzzi A: Fluid shear stress modulates surface expression of adhesion molecules by endothelial cells. Blood 1995;85:1696-1703.
17. Morigi M, Galbusera M, Binda E, Imberti B, Gastoldi S, Remuzzi A, Zoja C, Remuzzi G: Verotoxin-1-induced up-regulation of adhesive molecules renders microvascular endothelial cells thrombogenic at high shear stress. Blood 2001;98:1828-1835.
18. Slizova D, Krs O, Pospisilova B: Alternative method of rapid drying vascular specimens for scanning electron microscopy. J Endovasc Ther 2003;10:285-287. (Pubitemid 36988601)
19. Zucchi I, Montagna C, Susani L, Vezzoni P, Dulbecco R: The rat gene homologous to the human gene 9-27 is involved in the development of the mammary gland. Proc Natl Acad Sci USA 1998;95:1079-1084. (Pubitemid 28124915)
20. Cereijido M, Ehrenfeld J, Fernandez-Castelo S, Meza I: Fluxes, junctions, and blisters in cultured monolayers of epithelioid cells (MDCK). Ann NY Acad Sci 1981;372:422-441. (Pubitemid 12175079)
21. Laughery MD, Clifford RJ, Chi Y, Kaplan JH: Selective basolateral localization of overexpressed Na-K-ATPase beta1-and beta2-subunits is disrupted by butryate treatment of MDCK cells. Am J Physiol Renal Physiol 2007;292:F1718-1725. (Pubitemid 47105361)
22. Wilson PD, Devuyst O, Li X, Gatti L, Falkenstein D, Robinson S, Fambrough D, Burrow CR: Apical plasma membrane mispolarization of NaK-ATPase in polycystic kidney disease epithelia is associated with aberrant expression of the beta2 isoform. Am J Pathol 2000;156:253-268. (Pubitemid 30644459)
23. Chakraborty M, Chatterjee D, Gorelick FS, Baron R: Cell cycle-dependent and kinase-specific regulation of the apical Na/H exchanger and the Na,K-ATPase in the kidney cell line LLC-PK1 by calcitonin. Proc Natl Acad Sci USA 1994;91:2115-2119. (Pubitemid 24092053)
24. Su HW, Yeh HH, Wang SW, Shen MR, Chen TL, Kiela PR, Ghishan FK, Tang MJ: Cell confluence-induced activation of signal transducer and activator of transcription-3 (Stat3) triggers epithelial dome formation via augmentation of sodium hydrogen exchanger-3 (NHE3) expression. J Biol Chem 2007;282:9883-9894. (Pubitemid 47104639)
25. Kennedy BG, Lever JE: Regulation of Na+,K+-ATPase activity in MDCK kidney epithelial cell cultures: role of growth state, cyclic AMP, and chemical inducers of dome formation and differentiation. J Cell Physiol 1984;121:51-63. (Pubitemid 14017233)
26. Zucchi I, Montagna C, Susani L, Montesano R, Affer M, Zanotti S, Redolfi E, Vezzoni P, Dulbecco R: Genetic dissection of dome formation in a mammary cell line: identification of two genes with opposing action. Proc Natl Acad Sci USA 1999;96:13766-13770.
27. Chakrabarti A, Schatten H, Mitchell KD, Crosser M, Taylor M: Chloral hydrate alters the organization of the ciliary basal apparatus and cell organelles in sea urchin embryos. Cell Tissue Res 1998;293:453-462. (Pubitemid 28427328)
28. 2+ and cAMP signaling. Gastroenterology 2006;131:911-920. (Pubitemid 44307075)
29. Thomas SR, Schultz SG, Lever JE: Stimulation of dome formation in MDCK kidney epithelial cultures by inducers of differentiation: dissociation from effects on transepithelial resistance and cyclic AMP levels. J Cell Physiol 1982;113:427-432. (Pubitemid 13203847)
30. Hahn C, Schwartz MA: Mechanotransduction in vascular physiology and atherogenesis. Nat Rev Mol Cell Biol 2009;10:53-62.
31. Davies PF: Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology. Nat Clin Pract Cardiovasc Med 2009;6:16-26.
32. Wu CC, Li YS, Haga JH, Kaunas R, Chiu JJ, Su FC, Usami S, Chien S: Directional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry. Proc Natl Acad Sci USA 2007;104:1254-1259. (Pubitemid 46183991)
33. Duan Y, Gotoh N, Yan Q, Du Z, Weinstein AM, Wang T, Weinbaum S: Shear-induced reorganization of renal proximal tubule cell actin cytoskeleton and apical junctional complexes. Proc Natl Acad Sci USA 2008;105:11418-11423.
34. Girard PR, Nerem RM: Shear stress modulates endothelial cell morphology and F-actin organization through the regulation of focal adhesion-associated proteins. J Cell Physiol 1995;163:179-193.
35. Tzima E, Irani-Tehrani M, Kiosses WB, Dejana E, Schultz DA, Engelhardt B, Cao G, DeLisser H, Schwartz MA: A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature 2005;437:426-431. (Pubitemid 41613506)
36. Nauli SM, Rossetti S, Kolb RJ, Alenghat FJ, Consugar MB, Harris PC, Ingber DE, Loghman-Adham M, Zhou J: Loss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction. J Am Soc Nephrol 2006;17:1015-1025.
37. Weimbs T: Polycystic kidney disease and renal injury repair: common pathways, fluid flow, and the function of polycystin-1. Am J Physiol Renal Physiol 2007;293:F1423-1432. (Pubitemid 350085978)
38. Scheffers MS, van der Bent P, Prins F, Spruit L, Breuning MH, Litvinov SV, de Heer E, Peters DJ: Polycystin-1, the product of the polycystic kidney disease 1 gene, co-localizes with desmosomes in MDCK cells. Hum Mol Genet 2000;9:2743-2750.
39. Russo RJ, Husson H, Joly D, Bukanov NO, Patey N, Knebelmann B, Ibraghimov-Beskrovnaya O: Impaired formation of desmosomal junctions in ADPKD epithelia. Histochem Cell Biol 2005;124:487-497. (Pubitemid 41661364)