Crystallographic proof for an extended hydrogen-bonding network in small prolyl isomerases

Journal of the American Chemical Society

Volumn 133, Issue 50, 2011, Pages 20096-20099

  Mueller, Jonathan W ^a   Link, Nina M ^a,c   Matena, Anja ^a   Hoppstock, Lukas ^a   Rüppel, Alma ^a   Bayer, Peter ^a   Blankenfeldt, Wulf ^b,d  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY OF BAYREUTH   (Germany)

^c UNIVERSITY OF BASEL   (Switzerland)

^d MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC CAVITIES; CATALYTIC MECHANISMS; COMMON FEATURES; HYDROGEN ATOMS; HYDROGEN BONDING NETWORK; ISOMERASES; PROLYL ISOMERASE; PROTEIN QUALITY CONTROL; PROTEIN STABILITY; SIDE-CHAINS; THREONINE RESIDUES;

AMINO ACIDS; CRYSTAL ATOMIC STRUCTURE; ENZYMES; HYDROGEN; PROTEIN FOLDING; PROTEINS; QUANTUM CHEMISTRY;

CATALYST ACTIVITY;

HYDROGEN; MUTANT PROTEIN; PEPTIDYLPROLYL ISOMERASE; PEPTIDYLPROLYL ISOMERASE PAR14; PEPTIDYLPROLYL ISOMERASE PIN1; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ELECTRON; HYDROGEN BOND; PROTEIN DOMAIN; PROTEIN STABILITY;

CATALYSIS; HYDROGEN BONDING; MUTATION; PEPTIDYLPROLYL ISOMERASE; PROTEIN FOLDING;

EID: 83755168838     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja2086195     Document Type: Article

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