Altered distribution of mucosal NK cells during HIV infection

Mucosal Immunology

Volumn 5, Issue 1, 2012, Pages 30-40

  Sips, M ^a   Sciaranghella, G ^a   Diefenbach, T ^a   Dugast, A S ^a   Berger, C T ^a   Liu, Q ^a   Kwon, D ^a   Ghebremichael, M ^a   Estes, J D ^b   Carrington, M ^a,c   Martin, J N ^d   Deeks, S G ^d   Hunt, P W ^d   Alter, G ^a  

^a HARVARD UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SAIC FREDERICK INC   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; HLA ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR;

ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; GENOTYPE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; INTESTINE MUCOSA; INTRAEPITHELIAL LYMPHOCYTE; LAMINA PROPRIA; LYMPHOCYTE; NATURAL KILLER CELL; PRIORITY JOURNAL;

EID: 83655211619     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2011.40     Document Type: Article

References (51)

1. Brenchley, J. M. & Douek, D. C. The mucosal barrier and immune activation in HIV pathogenesis. Curr. Opin. HIV AIDS 3, 356-361 (2008). (Pubitemid 351521021)
2. Brenchley, J. M. & Douek, D. C. HIV infection and the gastrointestinalimmune system. Mucosal. Immunol. 1, 23-30 (2008).
3. Brenchley, J. M., et al. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J. Exp. Med. 200, 749-759 (2004). (Pubitemid 39299461)
4. Douek, D. C., et al. HIV preferentially infects HIV-specific CD4+ T cells. Nature 417, 95-98 (2002). (Pubitemid 34498823)
5. Clayton, F., et al. Rectal mucosal pathology varies with human immunodeficiency virus antigen content and disease stage. Gastroenterology 103, 919-933 (1992).
6. Rodgers, V. D., Fassett, R. & Kagnoff, M. F. Abnormalities in intestinal mucosal T cells in homosexual populations including those with the lymphadenopathy syndrome and acquired immunodeficiency syndrome. Gastroenterology 90, 552-558 (1986). (Pubitemid 16125858)
7. Mattapallil, J. J., et al. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 434, 1093-1097 (2005). (Pubitemid 40663481)
8. Brenchley, J. M., et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat. Med. 12, 1365-1371 (2006). (Pubitemid 44924494)
9. Pantaleo, G., Graziosi, C. & Fauci, A. S. Virologic and immunologic events in primary HIV infection. Springer Semin. Immunopathol. 18, 257-266 (1997). (Pubitemid 27113047)
10. Alter, G. & Altfeld, M. NK cells in HIV-1 infection: evidence for their role in the controlof HIV-1 infection. J. Intern. Med. 265, 29-42 (2009).
11. Alter, G., et al. Evolution of innate and adaptive effector cell functions during acute HIV-1 infection. J. Infect. Dis. 195, 1452-1460 (2007). (Pubitemid 46717463)
12. Berger, C. T. & Alter, G. Natural killer cells in spontaneous controlof HIV infection. Curr. Opin. HIV AIDS 6, 208-213 (2011).
13. Martin, M. P., et al. Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat. Genet. 31, 429-434 (2002). (Pubitemid 35154456)
14. Alter, G., et al. Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes. J. Exp. Med. 204, 3027-3036 (2007). (Pubitemid 350179568)
15. French, A. R. & Yokoyama, W. M. Natural killer cells and viralinfections. Curr. Opin. Immunol. 15, 45-51 (2003).
16. Collins, K. L. & Baltimore, D. HIVs evasion of the cellular immune response. Immunol. Rev. 168, 65-74 (1999). (Pubitemid 29276673)
17. De Maria, A., et al. The impaired NK cell cytolytic function in viremic HIV-1 infection is associated with a reduced surface expression of natural cytotoxicity receptors (NKp46, NKp30 and NKp44). Eur. J. Immunol. 33, 2410-2418 (2011).
18. Mavilio, D., et al. Characterization of CD56-/CD16+ natural killer (NK) cells: a highly dysfunctional NK subset expanded in HIV-infected viremic individuals. Proc. Natl Acad. Sci. USA 102, 2886-2891 (2005). (Pubitemid 40299886)
19. Fogli, M., et al. Significant NK cellactivation associated with decreased cytolytic function in peripheral blood of HIV-1-infected patients. Eur. J. Immunol. 34, 2313-2321 (2004). (Pubitemid 39256113)
20. Cai, Q., Huang, X. L., Rappocciolo, G. & Rinaldo, C. R. Jr. Natural killer cell responses in homosexual men with early HIV infection. J. Acquir. Immune Defic. Syndr. 3, 669-676 (1990). (Pubitemid 20375238)
21. Poli, G., et al. Natural killer cells in intravenous drug abusers with lymphadenopathy syndrome. Clin. Exp. Immunol. 62, 128-135 (1985). (Pubitemid 15229738)
22. Vieillard, V., Fausther-Bovendo, H., Samri, A. & Debre, P. Specific phenotypic and functional features of natural killer cells from HIV-infected long-term nonprogressors and HIV controllers. J. Acquir. Immune Defic. Syndr. 53, 564-573 (2010).
23. Wilson, A. D., Stokes, C. R. & Bourne, F. J. Morphology and functional characteristics of isolated porcine intraepithelial lymphocytes. Immunology 59, 109-113 (1986). (Pubitemid 16050076)
24. Chai, J. Y. & Lillehoj, H. S. Isolation and functional characterization of chicken intestinalintra-epithelial lymphocytes showing natural killer cellactivity against tumour target cells. Immunology 63, 111-117 (1988).
25. Flexman, J. P., Shellam, G. R. & Mayrhofer, G. Natural cytotoxicity, responsiveness to interferon and morphology of intra-epithelial lymphocytes from the smallintestine of the rat. Immunology 48, 733-741 (1983). (Pubitemid 13112464)
26. Tagliabue, A., Befus, A. D., Clark, D. A. & Bienenstock, J. Characteristics of natural killer cells in the murine intestinal epithelium and lamina propria. J. Exp. Med. 155, 1785-1796 (1982). (Pubitemid 12074215)
27. Chiba, M., Bartnik, W., ReMine, S. G., Thayer, W. R. & Shorter, R. G. Human colonic intraepithelialand lamina proprial lymphocytes: cytotoxicity in vitro and the potential effects of the isolation method on their functional properties. Gut 22, 177-186 (1981). (Pubitemid 11113583)
28. Eiras, P., et al. Intestinalintraepithelial lymphocytes contain a CD3-CD7+ subset expressing natural killer markers and a singular pattern of adhesion molecules. Scand. J. Immunol. 52, 1-6 (2000). (Pubitemid 30435978)
29. Leon, F., et al. Human small-intestinal epithelium contains functional natural killer lymphocytes. Gastroenterology 125, 345-356 (2003). (Pubitemid 36929414)
30. Carman, P. S., et al. Intraepithelial leukocytes contain a unique subpopulation of NK-like cytotoxic cells active in the defense of gut epithelium to enteric murine coronavirus. J. Immunol. 136, 1548-1553 (1986). (Pubitemid 16119555)
31. Cella, M., et al. A human natural killer cell subset provides an innate source of IL-22 for mucosalimmunity. Nature 457, 722-725 (2009).
32. Crellin, N. K., Trifari, S., Kaplan, C. D., Cupedo, T. & Spits, H. Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells. J. Exp. Med. 207, 281-290 (2010).
33. Arnaud-Battandier, F., Bundy, B. M., ONeill, M., Bienenstock, J. & Nelson, D. L. Cytotoxic activities of gut mucosal lymphoid cells in guinea pigs. J. Immunol. 121, 1059-1065 (1978). (Pubitemid 9007534)
34. Nauss, K. M., Pavlina, T. M., Kumar, V. & Newberne, P. M. Functional characteristics of lymphocytes isolated from the rat large intestine. Response to T-cell mitogens and natural killer cellactivity. Gastroenterology 86, 468-475 (1984). (Pubitemid 14154657)
35. Tagliabue, A., Luini, W., Soldateschi, D. & Boraschi, D. Natural killer activity of gut mucosal lymphoid cells in mice. Eur. J. Immunol. 11, 919-922 (1981). (Pubitemid 12253407)
36. Moretta, A., Bottino, C., Mingari, M. C., Biassoni, R. & Moretta, L. What is a natural killer cell? Nat. Immunol. 3, 6-8 (2002). (Pubitemid 34065607)
37. Lopez-Verges, S., et al. CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset. Blood 116, 3865-3874 (2010).
38. Hamperl, H. & Hellweg, G. Granular endometrial stroma cells. Obstet. Gynecol. 11, 379-387 (1958).
39. Martin, M. P., et al. Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat. Genet. 39, 733-740 (2007). (Pubitemid 46848586)
40. Schacker, T. W., et al. Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis. J. Clin. Invest. 110, 1133-1139 (2002). (Pubitemid 35215894)
41. Estes, J., et al. Collagen deposition limits immune reconstitution in the gut. J. Infect. Dis. 198, 456-464 (2008).
42. Veazey, R. S., et al. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science 280, 427-431 (1998). (Pubitemid 28208163)
43. Guadalupe, M., et al. Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J. Virol. 77, 11708-11717 (2003). (Pubitemid 37271669)
44. Mehandru, S., et al. Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract. J. Exp. Med. 200, 761-770 (2004). (Pubitemid 39299462)
45. Estes, J. D., et al. Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection. J. Infect. Dis. 195, 551-561 (2007). (Pubitemid 46214398)
46. Alter, G., et al. Single-stranded RNA derived from HIV-1 serves as a potent activator of NK cells. J. Immunol. 178, 7658-7666 (2007). (Pubitemid 46898036)
47. Poggi, A. & Zocchi, M. R. HIV-1 Tat triggers TGF-beta production and NK cellapoptosis that is prevented by pertussis toxin B. Clin. Dev. Immunol. 13, 369-372 (2006). (Pubitemid 44950053)
48. Parrott, D. M., et al. Analysis of the effector functions of different populations of mucosal lymphocytes. Ann. NY Acad. Sci. 409, 307-320 (1983). (Pubitemid 13057655)
49. Hunt, P. W., et al. Relationship between T cellactivation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. J. Infect. Dis. 197, 126-133 (2008). (Pubitemid 351263476)
50. Santamaria, M., Lopez-Beltran, A., Toro, M., Pena, J. & Molina, I. J. Specific monoclonalantibodies against leukocyte-restricted cell surface molecule CD43 react with nonhematopoietic tumor cells. Cancer Res. 56, 3526-3529 (1996). (Pubitemid 26251647)
51. Mendelson, M., et al. NKp46 O-glycan sequences that are involved in the interaction with hemagglutinin type 1 of infl uenza virus. J. Virol. 84, 3789-3797 (2010).