Amphetamine induced rotation in the assessment of lesions and grafts in the unilateral rat model of Parkinson's disease

European Neuropsychopharmacology

Volumn 17, Issue 3, 2007, Pages 206-214

  Torres, Eduardo M ^a   Dunnett, Stephen B ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

6 OHDA; Amphetamine; Animal model; Dopamine graft; Parkinson's disease; Rotation

Indexed keywords

AMPHETAMINE; DOPAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN GRAFT; CIRCLING BEHAVIOR; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

AMPHETAMINE; ANIMALS; BRAIN TISSUE TRANSPLANTATION; CENTRAL NERVOUS SYSTEM STIMULANTS; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETAL TISSUE TRANSPLANTATION; FUNCTIONAL LATERALITY; NEOSTRIATUM; PARKINSON DISEASE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; STEREOTYPED BEHAVIOR; SUBSTANTIA NIGRA;

EID: 33751196130     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2006.04.009     Document Type: Article

References (38)

1. Abercrombie M. Estimation of nuclear population from microtome sections. Anatomical Record 94 (1946) 239-247 (2004)
2. Annett L.E., Reading P.J., Tharumaratnam D., Abrous D.N., Torres E.M., and Dunnett S.B. Conditioning versus priming of dopaminergic grafts by amphetamine. Experimental Brain Research 93 (1993) 46-54
3. Bjorklund A., and Gage F.H. Neural grafting in animal models of neurodegenerative diseases. Annals of the New York Academy of Sciences 457 (1985) 53-81
4. Bjorklund A., Dunnett S.B., Stenevi U., Lewis M.E., and Iversen S.D. Reinnervation of the denervated striatum by substantia nigra transplants: functional consequences as revealed by pharmacological and sensorimotor testing. Brain Research 199 (1980) 307-333
5. Brundin P., and Bjorklund A. Survival, growth and function of dopaminergic neurons grafted to the brain. Progress in Brain Research 71 (1987) 293-308
6. Carey R.J. A conditioned anti-Parkinsonian drug effect in the hemi-Parkinsonian rat. Psychopharmacology (Berlin) 89 (1986) 269-272
7. Cragg S.J., Clarke D.J., and Greenfield S.A. Real-time dynamics of dopamine released from neuronal transplants in experimental Parkinson's disease. Experimental Neurology 164 (2000) 145-153
8. Creese I., and Iversen S.D. Blockage of amphetamine induced motor stimulation and stereotypy in the adult rat following neonatal treatment with 6-hydroxydopamine. Brain Research 55 (1973) 369-382
9. Creese I., and Iversen S.D. The role of forebrain dopamine systems in amphetamine induced stereotyped behavior in the rat. Psychopharmacologia 39 (1974) 345-357
10. Dowd E., and Dunnett S.B. Deficits in a lateralized associative learning task in dopamine-depleted rats with functional recovery by dopamine-rich transplants. European Journal of Neuroscience 20 (2004) 1953-1959
11. Dunnett S.B., and Bjorklund A. Basic neural transplantation techniques: I. Dissociated cell suspension grafts of embryonic ventral mesencephalon in the adult rat brain. Brain Research. Brain Research Protocols 1 (1997) 91-99
12. Dunnett S.B., and Robbins T.W. The functional role of mesotelencephalic dopamine systems. Biological Reviews of the Cambridge Philosophical Society 67 (1992) 491-518
13. Dunnett S.B., Bjorklund A., Schmidt R.H., Stenevi U., and Iversen S.D. Intracerebral grafting of neuronal cell suspensions. IV. Behavioural recovery in rats with unilateral 6-OHDA lesions following implantation of nigral cell suspensions in different forebrain sites. Acta Physiologica Scandinavica. Supplementuma 522 (1983) 29-37
14. Dunnett S.B., Hernandez T.D., Summerfield A., Jones G.H., and Arbuthnott G. Graft-derived recovery from 6-OHDA lesions: specificity of ventral mesencephalic graft tissues. Experimental Brain Research 71 (1988) 411-424
15. Dunnett S.B., Isacson O., Sirinathsinghji D.J., Clarke D.J., and Bjorklund A. Striatal grafts in rats with unilateral neostriatal lesions-III. Recovery from dopamine-dependent motor asymmetry and deficits in skilled paw reaching. Neuroscience 24 (1988) 813-820
16. Fawcett J., Rosser A.E., and Dunnet S.B. Brain Damage, Brain Repair. 1 edn. (2001), Oxford University Press
17. Gentry W.B., Ghafoor A.U., Wessinger W.D., Laurenzana E.M., Hendrickson H.P., and Owens S.M. (+)- Methamphetamine-induced spontaneous behavior in rats depends on route of (+) METH Administration. Pharmacology, Biochemistry and Behavior 79 (2004) 751-760
18. Herman J.P., Abrous D.N., and Le Moal M. Anatomical and behavioral comparison of unilateral dopamine-rich grafts implanted into the striatum of neonatal and adult rats. Neuroscience 40 (1991) 465-475
19. Herman J.P., Rouge-Pont F., Le Moal M., and Abrous D.N. Mechanisms of amphetamine-induced rotation in rats with unilateral intrastriatal grafts of embryonic dopaminergic neurons: a pharmacological and biochemical analysis. Neuroscience 53 (1993) 1083-1095
20. Iversen S.D., and Koob G.F. Behavioral implications of dopaminergic neurons in the mesolimbic system. Advances in Biochemical Psychopharmacology 16 (1977) 209-214
21. Kelly P.H., and Moore K.E. Mesolimbic dopaminergic neurones in the rotational model of nigrostriatal function. Nature 263 (1976) 695-696
22. Kelly P.H., and Moore K.E. Mesolimbic dopamine neurons: effects of 6-hydroxydopamine-induced destruction and receptor blockade on drug-induced rotation of rats. Psychopharmacology (Berlin) 55 (24-11-1977) 35-41
23. Kelly P.H., and Roberts D.C. Effects of amphetamine and apomorphine on locomotor activity after 6-OHDA and electrolytic lesions of the nucleus accumbens septi. Pharmacology, Biochemistry and Behavior 19 (1983) 137-143
24. Kelly P.H., Seviour P.W., and Iversen S.D. Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum. Brain Research 94 (1975) 507-522
25. Kuczenski R., Segal D.S., and Aizenstein M.L. Amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics. Journal of Neuroscience 11 (1991) 2703-2712
26. Kuczenski R., Melega W.P., Cho A.K., and Segal D.S. Extracellular dopamine and amphetamine after systemic amphetamine administration: comparison to the behavioral response. Journal of Pharmacology and Experimental Therapeutics 282 (1997) 591-596
27. Paxinos G., and Watson C. The Rat Brain in Sterotaxic Coordinates. 2nd edition (2003), Academic Press, London
28. Pycock C.J. Turning behaviour in animals. Neuroscience 5 (1980) 461-514
29. Pycock C.J., and Marsden C.D. The rotating rodent: a two component system?. European Journal of Pharmacology 47 (1978) 167-175
30. Randrup A., and Munkvad I. Pharmacology and physiology of stereotyped behavior. Journal of Psychiatric Research 11 (1974) 1-10
31. Rioux L., Gaudin D.P., Bui L.K., Gregoire L., DiPaolo T., and Bedard P.J. Correlation of functional recovery after a 6-hydroxydopamine lesion with survival of grafted fetal neurons and release of dopamine in the striatum of the rat. Neuroscience 40 (1991) 123-131
32. Schmidt R.H., Bjorklund A., Stenevi U., Dunnett S.B., and Gage F.H. Intracerebral grafting of neuronal cell suspensions. III. Activity of intrastriatal nigral suspension implants as assessed by measurements of dopamine synthesis and metabolism. Acta Physiologica Scandinavica. Supplementum 522 (1983) 19-28
33. Schwarting R.K., and Huston J.P. The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments. Progress in Neurobiology 50 (1996) 275-331
34. Ungerstedt U. Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system. Acta Physiologica Scandinavica. Supplementum 367 (1971) 69-93
35. Ungerstedt U. Striatal dopamine release after amphetamine or nerve degeneration revealed by rotational behaviour. Acta Physiologica Scandinavica. Supplementum 367 (1971) 49-68
36. Ungerstedt U., and Arbuthnott G.W. Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system. Brain Research 24 (1970) 485-493
37. Yurek D.M., and Fletcher-Turner A. Temporal changes in the neurotrophic environment of the denervated striatum as determined by the survival and outgrowth of grafted fetal dopamine neurons. Brain Research 931 (2002) 126-134
38. Ziegler M.G., and Szechtman H. Relation between motor asymmetry and direction of rotational behaviour under amphetamine and apomorphine in rats with unilateral degeneration of the nigrostriatal dopamine system. Behavioural Brain Research 39 (1990) 123-133