-
1
-
-
39849097306
-
The emerging role of the hippo pathway in cell contact inhibition, organ size control control, and cancer development in mammals
-
Zeng, Q. and Hong, W. (2008) The emerging role of the hippo pathway in cell contact inhibition, organ size control control, and cancer development in mammals. Cancer Cell 13, 188-192.
-
(2008)
Cancer Cell
, vol.13
, pp. 188-192
-
-
Zeng, Q.1
Hong, W.2
-
2
-
-
65649126416
-
The DeMSTification of mammalian Ste20 kinases
-
Radu, M. and Chernoff, J. (2009) The DeMSTification of mammalian Ste20 kinases. Curr. Biol. 19, R421-425.
-
(2009)
Curr. Biol.
, vol.19
-
-
Radu, M.1
Chernoff, J.2
-
3
-
-
0032522704
-
Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1
-
Graves, J. D., Gotoh, Y., Draves, K. E., Ambrose, D., Han, D. K., Wright, M., Chernoff, J., Clark, E. A. and Krebs, E. G. (1998) Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1. EMBO J. 17, 2224-2234.
-
(1998)
EMBO J
, vol.17
, pp. 2224-2234
-
-
Graves, J.D.1
Gotoh, Y.2
Draves, K.E.3
Ambrose, D.4
Han, D.K.5
Wright, M.6
Chernoff, J.7
Clark, E.A.8
Krebs, E.G.9
-
4
-
-
0034933130
-
MST1-JNK promotes apoptosis via caspase-dependent and independent pathways
-
Ura, S., Masuyama, N., Graves, J. D. and Gotoh, Y. (2001) MST1-JNK promotes apoptosis via caspase-dependent and independent pathways. Genes Cells 6, 519-530.
-
(2001)
Genes Cells
, vol.6
, pp. 519-530
-
-
Ura, S.1
Masuyama, N.2
Graves, J.D.3
Gotoh, Y.4
-
5
-
-
71049155850
-
Mst1-FoxO signaling protects Naive T lymphocytes from cellular oxidative stress in mice
-
Choi, J., Oh, S., Lee, D., Oh, H. J., Park, J. Y., Lee, S. B. and Lim, D. S. (2009) Mst1-FoxO signaling protects Naive T lymphocytes from cellular oxidative stress in mice. PLoS One 4, e8011.
-
(2009)
PLoS One
, vol.4
-
-
Choi, J.1
Oh, S.2
Lee, D.3
Oh, H.J.4
Park, J.Y.5
Lee, S.B.6
Lim, D.S.7
-
6
-
-
65649126736
-
Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes
-
Katagiri, K., Katakai, T., Ebisuno, Y., Ueda, Y., Okada, T. and Kinashi, T. (2009) Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes. EMBO J. 28, 1319-1331.
-
(2009)
EMBO J
, vol.28
, pp. 1319-1331
-
-
Katagiri, K.1
Katakai, T.2
Ebisuno, Y.3
Ueda, Y.4
Okada, T.5
Kinashi, T.6
-
7
-
-
71949114463
-
Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse
-
Oh, S., Lee, D., Kim, T., Kim, T. S., Oh, H. J., Hwang, C. Y., Kong, Y. Y., Kwon, K. S. and Lim, D. S. (2009) Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse. Mol. Cell. Biol. 29, 6309-6320.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 6309-6320
-
-
Oh, S.1
Lee, D.2
Kim, T.3
Kim, T.S.4
Oh, H.J.5
Hwang, C.Y.6
Kong, Y.Y.7
Kwon, K.S.8
Lim, D.S.9
-
8
-
-
41949138130
-
Tumor suppressor LATS1 is a negative regulator of oncogene YAP
-
Hao, Y., Chun, A., Cheung, K., Rashidi, B. and Yang, X. (2008) Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J. Biol. Chem. 283, 5496-5509.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5496-5509
-
-
Hao, Y.1
Chun, A.2
Cheung, K.3
Rashidi, B.4
Yang, X.5
-
9
-
-
35948961118
-
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
-
Zhao, B., Wei, X., Li, W., Udan, R. S., Yang, Q., Kim, J., Xie, J., Ikenoue, T., Yu, J., Li, L., Zheng, P., Ye, K., Chinnaiyan, A., Halder, G., Lai, Z. C. and Guan, K. L. (2007) Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev. 21, 2747-2761.
-
(2007)
Genes Dev
, vol.21
, pp. 2747-2761
-
-
Zhao, B.1
Wei, X.2
Li, W.3
Udan, R.S.4
Yang, Q.5
Kim, J.6
Xie, J.7
Ikenoue, T.8
Yu, J.9
Li, L.10
Zheng, P.11
Ye, K.12
Chinnaiyan, A.13
Halder, G.14
Lai, Z.C.15
Guan, K.L.16
-
10
-
-
23744458034
-
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
-
Huang, J., Wu, S., Barrera, J., Matthews, K. and Pan, D. (2005) The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 122, 421-434.
-
(2005)
Cell
, vol.122
, pp. 421-434
-
-
Huang, J.1
Wu, S.2
Barrera, J.3
Matthews, K.4
Pan, D.5
-
11
-
-
33646934067
-
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
-
Lehtinen, M. K., Yuan, Z., Boag, P. R., Yang, Y., Villen, J., Becker, E. B., DiBacco, S., de la Iglesia, N., Gygi, S., Blackwell, T. K. and Bonni, A. (2006) A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 125, 987-1001.
-
(2006)
Cell
, vol.125
, pp. 987-1001
-
-
Lehtinen, M.K.1
Yuan, Z.2
Boag, P.R.3
Yang, Y.4
Villen, J.5
Becker, E.B.6
DiBacco, S.7
de la Iglesia, N.8
Gygi, S.9
Blackwell, T.K.10
Bonni, A.11
-
12
-
-
65649149752
-
Regulation of neuronal cell death by MST1-FOXO1 signaling
-
Yuan, Z., Lehtinen, M. K., Merlo, P., Villen, J., Gygi, S. and Bonni, A. (2009) Regulation of neuronal cell death by MST1-FOXO1 signaling. J. Biol. Chem. 284, 11285-11292.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 11285-11292
-
-
Yuan, Z.1
Lehtinen, M.K.2
Merlo, P.3
Villen, J.4
Gygi, S.5
Bonni, A.6
-
13
-
-
11844276610
-
Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae
-
Ahn, S. H., Cheung, W. L., Hsu, J. Y., Diaz, R. L., Smith, M. M. and Allis, C. D. (2005) Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae. Cell 120, 25-36.
-
(2005)
Cell
, vol.120
, pp. 25-36
-
-
Ahn, S.H.1
Cheung, W.L.2
Hsu, J.Y.3
Diaz, R.L.4
Smith, M.M.5
Allis, C.D.6
-
14
-
-
0038293152
-
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase
-
Cheung, W. L., Ajiro, K., Samejima, K., Kloc, M., Cheung, P., Mizzen, C. A., Beeser, A., Etkin, L. D., Chernoff, J., Earnshaw, W. C. and Allis, C. D. (2003) Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell 113, 507-517.
-
(2003)
Cell
, vol.113
, pp. 507-517
-
-
Cheung, W.L.1
Ajiro, K.2
Samejima, K.3
Kloc, M.4
Cheung, P.5
Mizzen, C.A.6
Beeser, A.7
Etkin, L.D.8
Chernoff, J.9
Earnshaw, W.C.10
Allis, C.D.11
-
15
-
-
16444373346
-
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
-
Chan, E. H., Nousiainen, M., Chalamalasetty, R. B., Schafer, A., Nigg, E. A. and Sillje, H. H. (2005) The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene 24,2076-2086.
-
(2005)
Oncogene
, vol.24
, pp. 2076-2086
-
-
Chan, E.H.1
Nousiainen, M.2
Chalamalasetty, R.B.3
Schafer, A.4
Nigg, E.A.5
Sillje, H.H.6
-
16
-
-
0042232429
-
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
-
Wu, S., Huang, J., Dong, J. and Pan, D. (2003) hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell 114, 445-456.
-
(2003)
Cell
, vol.114
, pp. 445-456
-
-
Wu, S.1
Huang, J.2
Dong, J.3
Pan, D.4
-
17
-
-
42449101282
-
A crucial role of WW45 in developing epithelial tissues in the mouse
-
Lee, J. H., Kim, T. S., Yang, T. H., Koo, B. K., Oh, S. P., Lee, K. P., Oh, H. J., Lee, S. H., Kong, Y. Y., Kim, J. M. and Lim, D. S. (2008) A crucial role of WW45 in developing epithelial tissues in the mouse. EMBO J. 27, 1231-1242.
-
(2008)
EMBO J
, vol.27
, pp. 1231-1242
-
-
Lee, J.H.1
Kim, T.S.2
Yang, T.H.3
Koo, B.K.4
Oh, S.P.5
Lee, K.P.6
Oh, H.J.7
Lee, S.H.8
Kong, Y.Y.9
Kim, J.M.10
Lim, D.S.11
-
18
-
-
34547162995
-
Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway
-
Hwang, E., Ryu, K. S., Paakkonen, K., Guntert, P., Cheong, H. K., Lim, D. S., Lee, J. O., Jeon, Y. H. and Cheong, C. (2007) Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Proc. Natl. Acad. Sci. U. S. A. 104, 9236-9241.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 9236-9241
-
-
Hwang, E.1
Ryu, K.S.2
Paakkonen, K.3
Guntert, P.4
Cheong, H.K.5
Lim, D.S.6
Lee, J.O.7
Jeon, Y.H.8
Cheong, C.9
-
19
-
-
0037162714
-
Salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
-
Tapon, N., Harvey, K. F., Bell, D. W., Wahrer, D. C., Schiripo, T. A., Haber, D. A. and Hariharan, I. K. (2002) Salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110, 467-478.
-
(2002)
Cell
, vol.110
, pp. 467-478
-
-
Tapon, N.1
Harvey, K.F.2
Bell, D.W.3
Wahrer, D.C.4
Schiripo, T.A.5
Haber, D.A.6
Hariharan, I.K.7
-
20
-
-
33748308721
-
Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation
-
Callus, B. A., Verhagen, A. M. and Vaux, D. L. (2006) Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation. FEBS J. 273, 4264-4276.
-
(2006)
FEBS J
, vol.273
, pp. 4264-4276
-
-
Callus, B.A.1
Verhagen, A.M.2
Vaux, D.L.3
-
21
-
-
70549086229
-
Largescale proteomics analysis of the human kinome
-
Oppermann, F. S., Gnad, F., Olsen, J. V., Hornberger, R., Greff, Z., Keri, G., Mann, M. and Daub, H. (2009) Largescale proteomics analysis of the human kinome. Mol. Cell. Proteomics 8, 1751-1764.
-
(2009)
Mol. Cell. Proteomics
, vol.8
, pp. 1751-1764
-
-
Oppermann, F.S.1
Gnad, F.2
Olsen, J.V.3
Hornberger, R.4
Greff, Z.5
Keri, G.6
Mann, M.7
Daub, H.8
-
22
-
-
44149105911
-
PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites
-
Gnad, F., Ren, S., Cox, J., Olsen, J. V., Macek, B., Oroshi, M. and Mann, M. (2007) PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites. Genome Biol. 8, R250.
-
(2007)
Genome Biol
, vol.8
-
-
Gnad, F.1
Ren, S.2
Cox, J.3
Olsen, J.V.4
Macek, B.5
Oroshi, M.6
Mann, M.7
-
23
-
-
33846590071
-
Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma
-
Burgermeister, E., Chuderland, D., Hanoch, T., Meyer, M., Liscovitch, M. and Seger, R. (2007) Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma. Mol. Cell. Biol. 27, 803-817.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 803-817
-
-
Burgermeister, E.1
Chuderland, D.2
Hanoch, T.3
Meyer, M.4
Liscovitch, M.5
Seger, R.6
-
24
-
-
77950470207
-
Phosphoinositide 3-kinase/Akt inhibits MST1-mediated proapoptotic signaling through phosphorylation of threonine 120
-
Yuan, Z., Kim, D., Shu, S., Wu, J., Guo, J., Xiao, L., Kaneko, S., Coppola, D. and Cheng, J. Q. (2010) Phosphoinositide 3-kinase/Akt inhibits MST1-mediated proapoptotic signaling through phosphorylation of threonine 120. J. Biol. Chem. 285, 3815-3824.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 3815-3824
-
-
Yuan, Z.1
Kim, D.2
Shu, S.3
Wu, J.4
Guo, J.5
Xiao, L.6
Kaneko, S.7
Coppola, D.8
Cheng, J.Q.9
-
25
-
-
0037133034
-
Identification of a novel Ras-regulated proapoptotic pathway
-
Khokhlatchev, A., Rabizadeh, S., Xavier, R., Nedwidek, M., Chen, T., Zhang, X. F., Seed, B. and Avruch, J. (2002) Identification of a novel Ras-regulated proapoptotic pathway. Curr. Biol. 12, 253-265.
-
(2002)
Curr. Biol.
, vol.12
, pp. 253-265
-
-
Khokhlatchev, A.1
Rabizadeh, S.2
Xavier, R.3
Nedwidek, M.4
Chen, T.5
Zhang, X.F.6
Seed, B.7
Avruch, J.8
-
26
-
-
3142710380
-
The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death
-
Rabizadeh, S., Xavier, R. J., Ishiguro, K., Bernabeortiz, J., Lopez-Ilasaca, M., Khokhlatchev, A., Mollahan, P., Pfeifer, G. P., Avruch, J. and Seed, B. (2004) The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death. J. Biol. Chem. 279, 29247-29254.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29247-29254
-
-
Rabizadeh, S.1
Xavier, R.J.2
Ishiguro, K.3
Bernabeortiz, J.4
Lopez-Ilasaca, M.5
Khokhlatchev, A.6
Mollahan, P.7
Pfeifer, G.P.8
Avruch, J.9
Seed, B.10
|