메뉴 건너뛰기




Volumn 81, Issue 1, 2012, Pages 22-39

Systems biology of kidney diseases

Author keywords

cell signaling; gene transcription; kidney disease; microarray analysis; protein interaction

Indexed keywords

AMINOGUANIDINE; MESSENGER RNA; STEROID; SULODEXIDE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA ANTIBODY;

EID: 83655163844     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.314     Document Type: Review
Times cited : (75)

References (127)
  • 1
    • 79951521421 scopus 로고    scopus 로고
    • Progress and promise of genome-wide association studies for human complex trait genetics
    • Stranger BE, Stahl EA, Raj T. Progress and promise of genome-wide association studies for human complex trait genetics. Genetics 2010; 187: 367-383.
    • (2010) Genetics , vol.187 , pp. 367-383
    • Stranger, B.E.1    Stahl, E.A.2    Raj, T.3
  • 2
    • 67349175651 scopus 로고    scopus 로고
    • Multiple loci associated with indices of renal function and chronic kidney disease
    • Kottgen A, Glazer NL, Dehghan A et al. Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet 2009; 41: 712-717.
    • (2009) Nat Genet , vol.41 , pp. 712-717
    • Kottgen, A.1    Glazer, N.L.2    Dehghan, A.3
  • 3
    • 66649089156 scopus 로고    scopus 로고
    • Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes
    • Pezzolesi MG, Poznik GD, Mychaleckyj JC et al. Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes. Diabetes 2009; 58: 1403-1410.
    • (2009) Diabetes , vol.58 , pp. 1403-1410
    • Pezzolesi, M.G.1    Poznik, G.D.2    Mychaleckyj, J.C.3
  • 4
    • 38449087105 scopus 로고    scopus 로고
    • Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: The Family Investigation of Nephropathy and Diabetes (FIND)
    • Schelling JR, Abboud HE, Nicholas SB et al. Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND). Diabetes 2008; 57: 235-243.
    • (2008) Diabetes , vol.57 , pp. 235-243
    • Schelling, J.R.1    Abboud, H.E.2    Nicholas, S.B.3
  • 5
    • 77957886047 scopus 로고    scopus 로고
    • HLA has strongest association with IgA nephropathy in genome-wide analysis
    • Feehally J, Farrall M, Boland A et al. HLA has strongest association with IgA nephropathy in genome-wide analysis. J Am Soc Nephrol 2010; 21: 1791-1797.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1791-1797
    • Feehally, J.1    Farrall, M.2    Boland, A.3
  • 6
    • 52949092735 scopus 로고    scopus 로고
    • MYH9 is associated with nondiabetic end-stage renal disease in African Americans
    • Kao WH, Klag MJ, Meoni LA et al. MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nat Genet 2008; 40: 1185-1192.
    • (2008) Nat Genet , vol.40 , pp. 1185-1192
    • Kao, W.H.1    Klag, M.J.2    Meoni, L.A.3
  • 7
    • 52949110955 scopus 로고    scopus 로고
    • MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis
    • Kopp JB, Smith MW, Nelson GW et al. MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis. Nat Genet 2008; 40: 1175-1184.
    • (2008) Nat Genet , vol.40 , pp. 1175-1184
    • Kopp, J.B.1    Smith, M.W.2    Nelson, G.W.3
  • 8
    • 77956870511 scopus 로고    scopus 로고
    • A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9
    • Genovese G, Tonna SJ, Knob AU et al. A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9. Kidney Int 2010; 78: 698-704.
    • (2010) Kidney Int , vol.78 , pp. 698-704
    • Genovese, G.1    Tonna, S.J.2    Knob, A.U.3
  • 9
    • 74949135004 scopus 로고    scopus 로고
    • Planning and executing a genome wide association study (GWAS)
    • Sale MM, Mychaleckyj JC, Chen WM. Planning and executing a genome wide association study (GWAS). Methods Mol Biol 2009; 590: 403-418.
    • (2009) Methods Mol Biol , vol.590 , pp. 403-418
    • Sale, M.M.1    Mychaleckyj, J.C.2    Chen, W.M.3
  • 10
    • 79952600660 scopus 로고    scopus 로고
    • Genome-wide association studies
    • Iles MM. Genome-wide association studies. Methods Mol Biol 2011; 713: 89-103.
    • (2011) Methods Mol Biol , vol.713 , pp. 89-103
    • Iles, M.M.1
  • 11
    • 77955646179 scopus 로고    scopus 로고
    • Association of trypanolytic ApoL1 variants with kidney disease in African Americans
    • Genovese G, Friedman DJ, Ross MD et al. Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science 2010; 329: 841-845.
    • (2010) Science , vol.329 , pp. 841-845
    • Genovese, G.1    Friedman, D.J.2    Ross, M.D.3
  • 12
    • 67651108806 scopus 로고    scopus 로고
    • The genetics of quantitative traits: Challenges and prospects
    • Mackay TF, Stone EA, Ayroles JF. The genetics of quantitative traits: challenges and prospects. Nat Rev Genet 2009; 10: 565-577.
    • (2009) Nat Rev Genet , vol.10 , pp. 565-577
    • MacKay, T.F.1    Stone, E.A.2    Ayroles, J.F.3
  • 13
    • 66449090788 scopus 로고    scopus 로고
    • Susceptibility loci for murine HIVassociated nephropathy encode trans-regulators of podocyte gene expression
    • Papeta N, Chan KT, Prakash S et al. Susceptibility loci for murine HIVassociated nephropathy encode trans-regulators of podocyte gene expression. J Clin Invest 2009; 119: 1178-1188.
    • (2009) J Clin Invest , vol.119 , pp. 1178-1188
    • Papeta, N.1    Chan, K.T.2    Prakash, S.3
  • 14
    • 79952198057 scopus 로고    scopus 로고
    • Exome sequencing: The sweet spot before whole genomes
    • Teer JK, Mullikin JC. Exome sequencing: the sweet spot before whole genomes. Hum Mol Genet 2010; 19: R145-R151.
    • (2010) Hum Mol Genet , vol.19
    • Teer, J.K.1    Mullikin, J.C.2
  • 15
    • 73149123343 scopus 로고    scopus 로고
    • Genetic diagnosis by whole exome capture and massively parallel DNA sequencing
    • Choi M, Scholl UI, Ji W et al. Genetic diagnosis by whole exome capture and massively parallel DNA sequencing. Proc Natl Acad Sci USA 2009; 106: 19096-19101.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 19096-19101
    • Choi, M.1    Scholl, U.I.2    Ji, W.3
  • 16
    • 70249111091 scopus 로고    scopus 로고
    • Targeted capture and massively parallel sequencing of 12 human exomes
    • Ng SB, Turner EH, Robertson PD et al. Targeted capture and massively parallel sequencing of 12 human exomes. Nature 2009; 461: 272-276.
    • (2009) Nature , vol.461 , pp. 272-276
    • Ng, S.B.1    Turner, E.H.2    Robertson, P.D.3
  • 17
    • 54949157675 scopus 로고    scopus 로고
    • Defining human diabetic nephropathy on the molecular level: Integration of transcriptomic profiles with biological knowledge
    • Martini S, Eichinger F, Nair V et al. Defining human diabetic nephropathy on the molecular level: integration of transcriptomic profiles with biological knowledge. Rev Endocr Metab Disord 2008; 9: 267-274.
    • (2008) Rev Endocr Metab Disord , vol.9 , pp. 267-274
    • Martini, S.1    Eichinger, F.2    Nair, V.3
  • 18
    • 63249092534 scopus 로고    scopus 로고
    • Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy
    • Berthier CC, Zhang H, Schin M et al. Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy. Diabetes 2009; 58: 469-477.
    • (2009) Diabetes , vol.58 , pp. 469-477
    • Berthier, C.C.1    Zhang, H.2    Schin, M.3
  • 19
    • 77957365801 scopus 로고    scopus 로고
    • A molecular profile of focal segmental glomerulosclerosis from formalin-fixed, paraffin-embedded tissue
    • Hodgin JB, Borczuk AC, Nasr SH et al. A molecular profile of focal segmental glomerulosclerosis from formalin-fixed, paraffin-embedded tissue. Am J Pathol 2010; 177: 1674-1686.
    • (2010) Am J Pathol , vol.177 , pp. 1674-1686
    • Hodgin, J.B.1    Borczuk, A.C.2    Nasr, S.H.3
  • 21
    • 67049118905 scopus 로고    scopus 로고
    • Renal gene and protein expression signatures for prediction of kidney disease progression
    • Ju W, Eichinger F, Bitzer M et al. Renal gene and protein expression signatures for prediction of kidney disease progression. Am J Pathol 2009; 174: 2073-2085.
    • (2009) Am J Pathol , vol.174 , pp. 2073-2085
    • Ju, W.1    Eichinger, F.2    Bitzer, M.3
  • 22
    • 70349887791 scopus 로고    scopus 로고
    • Network analysis of genes regulated in renal diseases: Implications for a molecular-based classification
    • Bhavnani SK, Eichinger F, Martini S et al. Network analysis of genes regulated in renal diseases: implications for a molecular-based classification. BMC Bioinformatics 2009; 10(Suppl 9): S3.
    • (2009) BMC Bioinformatics , vol.10 , Issue.SUPPL. 9
    • Bhavnani, S.K.1    Eichinger, F.2    Martini, S.3
  • 25
    • 77950619219 scopus 로고    scopus 로고
    • NFkappaB promotes inflammation, coagulation, and fibrosis in the aging glomerulus
    • Wiggins JE, Patel SR, Shedden KA et al. NFkappaB promotes inflammation, coagulation, and fibrosis in the aging glomerulus. J Am Soc Nephrol 2010; 21: 587-597.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 587-597
    • Wiggins, J.E.1    Patel, S.R.2    Shedden, K.A.3
  • 26
    • 37749047490 scopus 로고    scopus 로고
    • Sequence census methods for functional genomics
    • Wold B, Myers RM. Sequence census methods for functional genomics. Nat Methods 2008; 5: 19-21.
    • (2008) Nat Methods , vol.5 , pp. 19-21
    • Wold, B.1    Myers, R.M.2
  • 27
    • 70449711243 scopus 로고    scopus 로고
    • Computation for ChIP-seq and RNA-seq studies
    • Pepke S, Wold B, Mortazavi A. Computation for ChIP-seq and RNA-seq studies. Nat Methods 2009; 6: S22-S32.
    • (2009) Nat Methods , vol.6
    • Pepke, S.1    Wold, B.2    Mortazavi, A.3
  • 28
    • 77957243164 scopus 로고    scopus 로고
    • ChEA: Transcription factor regulation inferred from integrating genome-wide ChIP-X experiments
    • Lachmann A, Xu H, Krishnan J et al. ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments. Bioinformatics 2010; 26: 2438-2444.
    • (2010) Bioinformatics , vol.26 , pp. 2438-2444
    • Lachmann, A.1    Xu, H.2    Krishnan, J.3
  • 29
    • 77954987489 scopus 로고    scopus 로고
    • Protein kinase target discovery from genome-wide messenger RNA expression profiling
    • Ma'ayan A, He JC. Protein kinase target discovery from genome-wide messenger RNA expression profiling. Mt Sinai J Med 2010; 77: 345-349.
    • (2010) Mt Sinai J Med , vol.77 , pp. 345-349
    • Ma'Ayan, A.1    He, J.C.2
  • 31
    • 55749100670 scopus 로고    scopus 로고
    • Epigenetics, development, and the kidney
    • Dressler GR. Epigenetics, development, and the kidney. J Am Soc Nephrol 2008; 19: 2060-2067.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2060-2067
    • Dressler, G.R.1
  • 32
    • 78049441535 scopus 로고    scopus 로고
    • Fine tuning gene expression: The epigenome
    • Mohtat D, Susztak K. Fine tuning gene expression: the epigenome. Semin Nephrol 2010; 30: 468-476.
    • (2010) Semin Nephrol , vol.30 , pp. 468-476
    • Mohtat, D.1    Susztak, K.2
  • 33
    • 77956230102 scopus 로고    scopus 로고
    • Genome-wide analysis of epigenetic signatures for kidney-specific transporters
    • Kikuchi R, Yagi S, Kusuhara H et al. Genome-wide analysis of epigenetic signatures for kidney-specific transporters. Kidney Int 2010; 78: 569-577.
    • (2010) Kidney Int , vol.78 , pp. 569-577
    • Kikuchi, R.1    Yagi, S.2    Kusuhara, H.3
  • 34
    • 77952116121 scopus 로고    scopus 로고
    • Methylation determines fibroblast activation and fibrogenesis in the kidney
    • Bechtel W, McGoohan S, Zeisberg EM et al. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat Med 2010; 16: 544-550.
    • (2010) Nat Med , vol.16 , pp. 544-550
    • Bechtel, W.1    McGoohan, S.2    Zeisberg, E.M.3
  • 35
    • 55749104549 scopus 로고    scopus 로고
    • Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury
    • Ho J, Ng KH, Rosen S et al. Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury. J Am Soc Nephrol 2008; 19: 2069-2075.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2069-2075
    • Ho, J.1    Ng, K.H.2    Rosen, S.3
  • 36
    • 55749112141 scopus 로고    scopus 로고
    • Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis
    • Shi S, Yu L, Chiu C et al. Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis. J Am Soc Nephrol 2008; 19: 2159-2169.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2159-2169
    • Shi, S.1    Yu, L.2    Chiu, C.3
  • 37
    • 77956279443 scopus 로고    scopus 로고
    • Identification of a microRNA signature of renal ischemia reperfusion injury
    • Godwin JG, Ge X, Stephan K et al. Identification of a microRNA signature of renal ischemia reperfusion injury. Proc Natl Acad Sci USA 2010; 107: 14339-14344.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14339-14344
    • Godwin, J.G.1    Ge, X.2    Stephan, K.3
  • 38
    • 77954274715 scopus 로고    scopus 로고
    • E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-beta
    • Wang B, Herman-Edelstein M, Koh P et al. E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-beta. Diabetes 2010; 59: 1794-1802.
    • (2010) Diabetes , vol.59 , pp. 1794-1802
    • Wang, B.1    Herman-Edelstein, M.2    Koh, P.3
  • 39
    • 77955611511 scopus 로고    scopus 로고
    • MiR-192 mediates TGF-beta/Smad3-driven renal fibrosis
    • Chung AC, Huang XR, Meng X et al. miR-192 mediates TGF-beta/Smad3-driven renal fibrosis. J Am Soc Nephrol 2010; 21: 1317-1325.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1317-1325
    • Chung, A.C.1    Huang, X.R.2    Meng, X.3
  • 40
    • 77949892330 scopus 로고    scopus 로고
    • Loss of MicroRNA-192 promotes fibrogenesis in diabetic nephropathy
    • Krupa A, Jenkins R, Luo DD et al. Loss of MicroRNA-192 promotes fibrogenesis in diabetic nephropathy. J Am Soc Nephrol 2010; 21: 438-447.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 438-447
    • Krupa, A.1    Jenkins, R.2    Luo, D.D.3
  • 41
    • 48749122914 scopus 로고    scopus 로고
    • Circulating microRNAs as stable blood-based markers for cancer detection
    • Mitchell PS, Parkin RK, Kroh EM et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci USA 2008; 105: 10513-10518.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10513-10518
    • Mitchell, P.S.1    Parkin, R.K.2    Kroh, E.M.3
  • 42
    • 34347376692 scopus 로고    scopus 로고
    • Characterization of microRNA expression profiles in normal human tissues
    • Liang Y, Ridzon D, Wong L et al. Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 2007; 8: 166.
    • (2007) BMC Genomics , vol.8 , pp. 166
    • Liang, Y.1    Ridzon, D.2    Wong, L.3
  • 43
    • 11844262661 scopus 로고    scopus 로고
    • Phylogenetic shadowing and computational identification of human microRNA genes
    • DOI 10.1016/j.cell.2004.12.031, PII S0092867404012565
    • Berezikov E, Guryev V, van de Belt J et al. Phylogenetic shadowing and computational identification of human microRNA genes. Cell 2005; 120: 21-24. (Pubitemid 40094599)
    • (2005) Cell , vol.120 , Issue.1 , pp. 21-24
    • Berezikov, E.1    Guryev, V.2    Van De Belt, J.3    Wienholds, E.4    Plasterk, R.H.A.5    Cuppen, E.6
  • 44
    • 52249088665 scopus 로고    scopus 로고
    • Transrenal nucleic acids: From proof of principle to clinical tests
    • Melkonyan HS, Feaver WJ, Meyer E et al. Transrenal nucleic acids: from proof of principle to clinical tests. Ann NY Acad Sci 2008; 1137: 73-81.
    • (2008) Ann NY Acad Sci , vol.1137 , pp. 73-81
    • Melkonyan, H.S.1    Feaver, W.J.2    Meyer, E.3
  • 45
    • 33747252210 scopus 로고    scopus 로고
    • The application of DIGE-based proteomics to renal physiology
    • Hoorn EJ, Hoffert JD, Knepper MA. The application of DIGE-based proteomics to renal physiology. Nephron Physiol 2006; 104: p61-p72.
    • (2006) Nephron Physiol , vol.104
    • Hoorn, E.J.1    Hoffert, J.D.2    Knepper, M.A.3
  • 52
    • 42549102138 scopus 로고    scopus 로고
    • Urinary biomarkers for acute kidney injury: Perspectives on translation
    • Coca SG, Parikh CR. Urinary biomarkers for acute kidney injury: perspectives on translation. Clin J Am Soc Nephrol 2008; 3: 481-490.
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 481-490
    • Coca, S.G.1    Parikh, C.R.2
  • 53
    • 36549025838 scopus 로고    scopus 로고
    • Proteomics for biomarker discovery in acute kidney injury
    • DOI 10.1016/j.semnephrol.2007.09.005, PII S0270929507001295, Proteomics and the Kidney
    • Devarajan P. Proteomics for biomarker discovery in acute kidney injury. Semin Nephrol 2007; 27: 637-651. (Pubitemid 350180173)
    • (2007) Seminars in Nephrology , vol.27 , Issue.6 , pp. 637-651
    • Devarajan, P.1
  • 54
    • 36549001613 scopus 로고    scopus 로고
    • Proteomics and diabetic nephropathy
    • DOI 10.1016/j.semnephrol.2007.09.003, PII S027092950700126X, Proteomics and the Kidney
    • Merchant ML, Klein JB. Proteomics and diabetic nephropathy. Semin Nephrol 2007; 27: 627-636. (Pubitemid 350180170)
    • (2007) Seminars in Nephrology , vol.27 , Issue.6 , pp. 627-636
    • Merchant, M.L.1    Klein, J.B.2
  • 55
    • 48149087279 scopus 로고    scopus 로고
    • Urinary proteomics in diabetes and CKD
    • Rossing K, Mischak H, Dakna M et al. Urinary proteomics in diabetes and CKD. J Am Soc Nephrol 2008; 19: 1283-1290.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1283-1290
    • Rossing, K.1    Mischak, H.2    Dakna, M.3
  • 57
    • 73849127049 scopus 로고    scopus 로고
    • Application of proteomic analysis to the study of renal diseases
    • Smith MP, Banks RE, Wood SL et al. Application of proteomic analysis to the study of renal diseases. Nat Rev Nephrol 2009; 5: 701-712.
    • (2009) Nat Rev Nephrol , vol.5 , pp. 701-712
    • Smith, M.P.1    Banks, R.E.2    Wood, S.L.3
  • 58
    • 77956125132 scopus 로고    scopus 로고
    • Proteomic biomarkers in diabetic nephropathy-reality or future promise?
    • Mischak H, Rossing P. Proteomic biomarkers in diabetic nephropathy-reality or future promise? Nephrol Dial Transplant 2010; 25: 2843-2845.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 2843-2845
    • Mischak, H.1    Rossing, P.2
  • 59
    • 78049421465 scopus 로고    scopus 로고
    • Proteomics database in chronic kidney disease
    • Yamamoto T. Proteomics database in chronic kidney disease. Adv Chronic Kidney Dis 2010; 17: 487-492.
    • (2010) Adv Chronic Kidney Dis , vol.17 , pp. 487-492
    • Yamamoto, T.1
  • 60
    • 33947396353 scopus 로고    scopus 로고
    • Standardized peptidome profiling of human urine by magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
    • DOI 10.1373/clinchem.2006.077834
    • Fiedler GM, Baumann S, Leichtle A et al. Standardized peptidome profiling of human urine by magnetic bead separation and matrixassisted laser desorption/ionization time-of-flight mass spectrometry. Clin Chem 2007; 53: 421-428. (Pubitemid 46447938)
    • (2007) Clinical Chemistry , vol.53 , Issue.3 , pp. 421-428
    • Fiedler, G.M.1    Baumann, S.2    Leichtle, A.3    Oltmann, A.4    Kase, J.5    Thiery, J.6    Ceglarek, U.7
  • 61
    • 0036007687 scopus 로고    scopus 로고
    • Metabolomics-The link between genotypes and phenotypes
    • Fiehn O. Metabolomics-the link between genotypes and phenotypes. Plant Mol Biol 2002; 48: 155-171.
    • (2002) Plant Mol Biol , vol.48 , pp. 155-171
    • Fiehn, O.1
  • 62
    • 36549029196 scopus 로고    scopus 로고
    • Metabolomics as an Extension of Proteomic Analysis: Study of Acute Kidney Injury
    • DOI 10.1016/j.semnephrol.2007.09.006, PII S0270929507001258, Proteomics and the Kidney
    • Portilla D, Schnackenberg L, Beger RD. Metabolomics as an extension of proteomic analysis: study of acute kidney injury. Semin Nephrol 2007; 27: 609-620. (Pubitemid 350180169)
    • (2007) Seminars in Nephrology , vol.27 , Issue.6 , pp. 609-620
    • Portilla, D.1    Schnackenberg, L.2    Beger, R.D.3
  • 63
    • 48949096538 scopus 로고    scopus 로고
    • Metabolomics: A complementary tool in renal transplantation
    • Wishart DS. Metabolomics: a complementary tool in renal transplantation. Contrib Nephrol 2008; 160: 76-87.
    • (2008) Contrib Nephrol , vol.160 , pp. 76-87
    • Wishart, D.S.1
  • 64
    • 77955646193 scopus 로고    scopus 로고
    • Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
    • Mendez-Ferrer S, Michurina TV, Ferraro F et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 2010; 466: 829-834.
    • (2010) Nature , vol.466 , pp. 829-834
    • Mendez-Ferrer, S.1    Michurina, T.V.2    Ferraro, F.3
  • 65
    • 77949431355 scopus 로고    scopus 로고
    • Lists2Networks: Integrated analysis of gene/protein lists
    • Lachmann A, Ma'ayan A. Lists2Networks: integrated analysis of gene/protein lists. BMC Bioinformatics 2010; 11: 87.
    • (2010) BMC Bioinformatics , vol.11 , pp. 87
    • Lachmann, A.1    Ma'Ayan, A.2
  • 67
    • 0034887203 scopus 로고    scopus 로고
    • Creating the gene ontology resource: Design and implementation
    • Gene Ontology Consortium
    • Gene Ontology Consortium. Creating the gene ontology resource: design and implementation. Genome Res 2001; 11: 1425-1433.
    • (2001) Genome Res , vol.11 , pp. 1425-1433
  • 68
    • 17644427718 scopus 로고    scopus 로고
    • Causal protein-signaling networks derived from multiparameter single-cell data
    • DOI 10.1126/science.1105809
    • Sachs K, Perez O, Pe'er D et al. Causal protein-signaling networks derived from multiparameter single-cell data. Science 2005; 308: 523-529. (Pubitemid 40570578)
    • (2005) Science , vol.308 , Issue.5721 , pp. 523-529
    • Sachs, K.1    Perez, O.2    Pe'er, D.3    Lauffenburger, D.A.4    Nolan, G.P.5
  • 69
    • 52949087576 scopus 로고    scopus 로고
    • A genomewide functional network for the laboratory mouse
    • Guan Y, Myers CL, Lu R et al. A genomewide functional network for the laboratory mouse. PLoS Comput Biol 2008; 4: e1000165.
    • (2008) PLoS Comput Biol , vol.4
    • Guan, Y.1    Myers, C.L.2    Lu, R.3
  • 70
    • 0034666108 scopus 로고    scopus 로고
    • STRING: A web-server to retrieve and display the repeatedly occurring neighbourhood of a gene
    • Snel B, Lehmann G, Bork P et al. STRING: a web-server to retrieve and display the repeatedly occurring neighbourhood of a gene. Nucleic Acids Res 2000; 28: 3442-3444.
    • (2000) Nucleic Acids Res , vol.28 , pp. 3442-3444
    • Snel, B.1    Lehmann, G.2    Bork, P.3
  • 71
    • 65349085291 scopus 로고    scopus 로고
    • Global networks of functional coupling in eukaryotes from comprehensive data integration
    • Alexeyenko A, Sonnhammer EL. Global networks of functional coupling in eukaryotes from comprehensive data integration. Genome Res 2009; 19: 1107-1116.
    • (2009) Genome Res , vol.19 , pp. 1107-1116
    • Alexeyenko, A.1    Sonnhammer, E.L.2
  • 72
    • 33947305781 scopus 로고    scopus 로고
    • ARACNE: An algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context
    • Margolin AA, Nemenman I, Basso K et al. ARACNE: an algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context. BMC Bioinformatics 2006; 7(Suppl 1): S7.
    • (2006) BMC Bioinformatics , vol.7 , Issue.SUPPL. 1
    • Margolin, A.A.1    Nemenman, I.2    Basso, K.3
  • 74
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • Friedman RC, Farh KK, Burge CB et al. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 2009; 19: 92-105.
    • (2009) Genome Res , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3
  • 77
    • 54049158517 scopus 로고    scopus 로고
    • Network integration and graph analysis in mammalian molecular systems biology
    • Ma'ayan A. Network integration and graph analysis in mammalian molecular systems biology. IET Syst Biol 2008; 2: 206-221.
    • (2008) IET Syst Biol , vol.2 , pp. 206-221
    • Ma'Ayan, A.1
  • 78
    • 84903814068 scopus 로고    scopus 로고
    • SAPHIR-A multi-scale, multiresolution modeling environment targeting blood pressure regulation and fluid homeostasis
    • Thomas S, Abdulhay E, Baconnier P et al. SAPHIR-a multi-scale, multiresolution modeling environment targeting blood pressure regulation and fluid homeostasis. Conf Proc IEEE Eng Med Biol Soc 2007; 2007: 6649-6652.
    • (2007) Conf Proc IEEE Eng Med Biol Soc , vol.2007 , pp. 6649-6652
    • Thomas, S.1    Abdulhay, E.2    Baconnier, P.3
  • 79
    • 48349110500 scopus 로고    scopus 로고
    • SAPHIR: A physiome core model of body fluid homeostasis and blood pressure regulation
    • Thomas SR, Baconnier P, Fontecave J et al. SAPHIR: a physiome core model of body fluid homeostasis and blood pressure regulation. Philos Transact A Math Phys Eng Sci 2008; 366: 3175-3197.
    • (2008) Philos Transact A Math Phys Eng Sci , vol.366 , pp. 3175-3197
    • Thomas, S.R.1    Baconnier, P.2    Fontecave, J.3
  • 80
    • 29144453338 scopus 로고    scopus 로고
    • Long-term mathematical model involving renal sympathetic nerve activity, arterial pressure, and sodium excretion
    • DOI 10.1007/s10439-005-5976-4
    • Karaaslan F, Denizhan Y, Kayserilioglu A et al. Long-term mathematical model involving renal sympathetic nerve activity, arterial pressure, and sodium excretion. Ann Biomed Eng 2005; 33: 1607-1630. (Pubitemid 41801646)
    • (2005) Annals of Biomedical Engineering , vol.33 , Issue.11 , pp. 1607-1630
    • Karaaslan, F.1    Denizhan, Y.2    Kayserilioglu, A.3    Gulcur, H.O.4
  • 85
    • 0037404898 scopus 로고    scopus 로고
    • Mathematical models of renal fluid and electrolyte transport: Acknowledging our uncertainty
    • Weinstein AM. Mathematical models of renal fluid and electrolyte transport: acknowledging our uncertainty. Am J Physiol Renal Physiol 2003; 284: F871-F884. (Pubitemid 36443571)
    • (2003) American Journal of Physiology - Renal Physiology , vol.284 , Issue.5
    • Weinstein, A.M.1
  • 86
    • 0028842467 scopus 로고
    • Analysis of interaction between TGF and the myogenic response in renal blood flow autoregulation
    • Feldberg R, Colding-Jorgensen M, Holstein-Rathlou NH. Analysis of interaction between TGF and the myogenic response in renal blood flow autoregulation. Am J Physiol 1995; 269: F581-F593.
    • (1995) Am J Physiol , vol.269
    • Feldberg, R.1    Colding-Jorgensen, M.2    Holstein-Rathlou, N.H.3
  • 89
    • 0019513182 scopus 로고
    • A network thermodynamic model of glomerular dynamics: Application in the rat
    • Oken DE, Thomas SR, Mikulecky DC. A network thermodynamic model of glomerular dynamics: application in the rat. Kidney Int 1981; 19: 359-373. (Pubitemid 11145618)
    • (1981) Kidney International , vol.19 , Issue.2 , pp. 359-373
    • Oken, D.E.1    Thomas, S.R.2    Mikulecky, D.C.3
  • 90
  • 92
    • 0031657107 scopus 로고    scopus 로고
    • Insights from mathematical modeling of renal tubular function
    • Weinstein AM. Insights from mathematical modeling of renal tubular function. Exp Nephrol 1998; 6: 462-468. (Pubitemid 28439335)
    • (1998) Experimental Nephrology , vol.6 , Issue.5 , pp. 462-468
    • Weinstein, A.M.1
  • 93
    • 33645451233 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of the mouse nephron
    • Zhai XY, Thomsen JS, Birn H et al. Three-dimensional reconstruction of the mouse nephron. J Am Soc Nephrol 2006; 17: 77-88.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 77-88
    • Zhai, X.Y.1    Thomsen, J.S.2    Birn, H.3
  • 94
    • 34548627230 scopus 로고    scopus 로고
    • Three-dimensional architecture of collecting ducts, loops of Henle, and blood vessels in the renal papilla
    • DOI 10.1152/ajprenal.00231.2007
    • Pannabecker TL, Dantzler WH. Three-dimensional architecture of collecting ducts, loops of Henle, and blood vessels in the renal papilla. Am J Physiol Renal Physiol 2007; 293: F696-F704. (Pubitemid 47403339)
    • (2007) American Journal of Physiology - Renal Physiology , vol.293 , Issue.3
    • Pannabecker, T.L.1    Dantzler, W.H.2
  • 97
    • 23944442318 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of glomeruli by electron microscopy reveals a distinct restrictive urinary subpodocyte space
    • DOI 10.1681/ASN.2004100822
    • Neal CR, Crook H, Bell E et al. Three-dimensional reconstruction of glomeruli by electron microscopy reveals a distinct restrictive urinary subpodocyte space. J Am Soc Nephrol 2005; 16: 1223-1235. (Pubitemid 41716507)
    • (2005) Journal of the American Society of Nephrology , vol.16 , Issue.5 , pp. 1223-1235
    • Neal, C.R.1    Crook, H.2    Bell, E.3    Harper, S.J.4    Bates, D.O.5
  • 98
    • 78649829302 scopus 로고    scopus 로고
    • Imaging of the porous ultrastructure of the glomerular epithelial filtration slit
    • Gagliardini E, Conti S, Benigni A et al. Imaging of the porous ultrastructure of the glomerular epithelial filtration slit. J Am Soc Nephrol 2010; 21: 2081-2089.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 2081-2089
    • Gagliardini, E.1    Conti, S.2    Benigni, A.3
  • 99
    • 67449089661 scopus 로고    scopus 로고
    • The virtual cell-A candidate co-ordinator for 0middle-out0 modelling of biological systems
    • Walker DC, Southgate J. The virtual cell-a candidate co-ordinator for 0middle-out0 modelling of biological systems. Brief Bioinform 2009; 10: 450-461.
    • (2009) Brief Bioinform , vol.10 , pp. 450-461
    • Walker, D.C.1    Southgate, J.2
  • 100
    • 74749106342 scopus 로고    scopus 로고
    • Novel clinico-genome network modeling for revolutionizing genotype-phenotype-based personalized cancer care
    • Roukos DH. Novel clinico-genome network modeling for revolutionizing genotype-phenotype-based personalized cancer care. Expert Rev Mol Diagn 2010; 10: 33-48.
    • (2010) Expert Rev Mol Diagn , vol.10 , pp. 33-48
    • Roukos, D.H.1
  • 101
    • 53049110295 scopus 로고    scopus 로고
    • Genomic analysis in nephrology-towards systems biology and systematic medicine?
    • Neusser MA, Lindenmeyer MT, Kretzler M et al. Genomic analysis in nephrology-towards systems biology and systematic medicine? Nephrol Ther 2008; 4: 306-311.
    • (2008) Nephrol Ther , vol.4 , pp. 306-311
    • Neusser, M.A.1    Lindenmeyer, M.T.2    Kretzler, M.3
  • 102
    • 61349193079 scopus 로고    scopus 로고
    • Hypoxia response and VEGF-A expression in human proximal tubular epithelial cells in stable and progressive renal disease
    • Rudnicki M, Perco P, Enrich J et al. Hypoxia response and VEGF-A expression in human proximal tubular epithelial cells in stable and progressive renal disease. Lab Invest 2009; 89: 337-346.
    • (2009) Lab Invest , vol.89 , pp. 337-346
    • Rudnicki, M.1    Perco, P.2    Enrich, J.3
  • 103
    • 67249125789 scopus 로고    scopus 로고
    • Systems biology of autosomal dominant polycystic kidney disease (ADPKD): Computational identification of gene expression pathways and integrated regulatory networks
    • Song X, Di Giovanni V, He N et al. Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks. Hum Mol Genet 2009; 18: 2328-2343.
    • (2009) Hum Mol Genet , vol.18 , pp. 2328-2343
    • Song, X.1    Di Giovanni, V.2    He, N.3
  • 105
    • 58949083257 scopus 로고    scopus 로고
    • Genetic and phenotypic analysis of B-cell post-transplant lymphoproliferative disorders provides insights into disease biology
    • Vakiani E, Basso K, Klein U et al. Genetic and phenotypic analysis of B-cell post-transplant lymphoproliferative disorders provides insights into disease biology. Hematol Oncol 2008; 26: 199-211.
    • (2008) Hematol Oncol , vol.26 , pp. 199-211
    • Vakiani, E.1    Basso, K.2    Klein, U.3
  • 107
    • 0022396335 scopus 로고
    • Effect of captopril on heavy proteinuria in azotemic diabetics
    • Taguma Y, Kitamoto Y, Futaki G et al. Effect of captopril on heavy proteinuria in azotemic diabetics. N Engl J Med 1985; 313: 1617-1620. (Pubitemid 16155665)
    • (1985) New England Journal of Medicine , vol.313 , Issue.26 , pp. 1617-1620
    • Taguma, Y.1    Kitamoto, Y.2    Futaki, G.3
  • 108
    • 0027517659 scopus 로고
    • The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy
    • DOI 10.1056/NEJM199311113292004
    • Lewis EJ, Hunsicker LG, Bain RP et al. The effect of angiotensinconverting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group. N Engl J Med 1993; 329: 1456-1462. (Pubitemid 23335891)
    • (1993) New England Journal of Medicine , vol.329 , Issue.20 , pp. 1456-1462
    • Lewis, E.J.1    Hunsicker, L.G.2    Bain, R.P.3    Rohde, R.D.4
  • 109
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Hunsicker LG, Clarke WR et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345: 851-860.
    • (2001) N Engl J Med , vol.345 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 110
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • Brenner BM, Cooper ME, de Zeeuw D et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345: 861-869.
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    De Zeeuw, D.3
  • 111
    • 0035922444 scopus 로고    scopus 로고
    • The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
    • Parving HH, Lehnert H, Brochner-Mortensen J et al. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001; 345: 870-878.
    • (2001) N Engl J Med , vol.345 , pp. 870-878
    • Parving, H.H.1    Lehnert, H.2    Brochner-Mortensen, J.3
  • 113
    • 0142074864 scopus 로고    scopus 로고
    • Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts
    • DOI 10.1016/j.abb.2003.08.013
    • Thornalley PJ. Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts. Arch Biochem Biophys 2003; 419: 31-40. (Pubitemid 37279141)
    • (2003) Archives of Biochemistry and Biophysics , vol.419 , Issue.1 , pp. 31-40
    • Thornalley, P.J.1
  • 114
    • 79952196548 scopus 로고    scopus 로고
    • Role of the retinoic acid receptoralpha in HIV-associated nephropathy
    • Ratnam KK, Feng X, Chuang PY et al. Role of the retinoic acid receptoralpha in HIV-associated nephropathy. Kidney Int 2011; 79: 624-634.
    • (2011) Kidney Int , vol.79 , pp. 624-634
    • Ratnam, K.K.1    Feng, X.2    Chuang, P.Y.3
  • 116
    • 77952834144 scopus 로고    scopus 로고
    • Linking transcriptomic and proteomic data on the level of protein interaction networks
    • Perco P, Muhlberger I, Mayer G et al. Linking transcriptomic and proteomic data on the level of protein interaction networks. Electrophoresis 2010; 31: 1780-1789.
    • (2010) Electrophoresis , vol.31 , pp. 1780-1789
    • Perco, P.1    Muhlberger, I.2    Mayer, G.3
  • 118
    • 33847003364 scopus 로고    scopus 로고
    • Expression pattern of genes in peripheral blood mononuclear cells in diabetic nephropathy
    • Moczulski DK, Fojcik H, Wielgorecki A et al. Expression pattern of genes in peripheral blood mononuclear cells in diabetic nephropathy. Diabet Med 2007; 24: 266-271.
    • (2007) Diabet Med , vol.24 , pp. 266-271
    • Moczulski, D.K.1    Fojcik, H.2    Wielgorecki, A.3
  • 119
    • 22044440445 scopus 로고    scopus 로고
    • Two-dimensional fluorescence difference gel electrophoresis analysis of the urine proteome in human diabetic nephropathy
    • DOI 10.1002/pmic.200401288
    • Sharma K, Lee S, Han S et al. Two-dimensional fluorescence difference gel electrophoresis analysis of the urine proteome in human diabetic nephropathy. Proteomics 2005; 5: 2648-2655. (Pubitemid 40966492)
    • (2005) Proteomics , vol.5 , Issue.10 , pp. 2648-2655
    • Sharma, K.1    Lee, S.2    Han, S.3    Lee, S.4    Francos, B.5    McCue, P.6    Wassell, R.7    Shaw, M.A.8    RamachandraRao, S.P.9
  • 122
    • 33847395363 scopus 로고    scopus 로고
    • Proteome analysis of serum from type 2 diabetics with nephropathy
    • Kim HJ, Cho EH, Yoo JH et al. Proteome analysis of serum from type 2 diabetics with nephropathy. J Proteome Res 2007; 6: 735-743.
    • (2007) J Proteome Res , vol.6 , pp. 735-743
    • Kim, H.J.1    Cho, E.H.2    Yoo, J.H.3
  • 124
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNAmRNA interaction maps
    • Chi SW, Zang JB, Mele A et al. Argonaute HITS-CLIP decodes microRNAmRNA interaction maps. Nature 2009; 460: 479-486.
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3
  • 125
    • 36349011849 scopus 로고    scopus 로고
    • Genes2Networks: Connecting lists of gene symbols using mammalian protein interactions databases
    • Berger SI, Posner JM, Ma'ayan A. Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases. BMC Bioinformatics 2007; 8: 372.
    • (2007) BMC Bioinformatics , vol.8 , pp. 372
    • Berger, S.I.1    Posner, J.M.2    Ma'Ayan, A.3
  • 126
    • 61449203001 scopus 로고    scopus 로고
    • KEA: Kinase enrichment analysis
    • Lachmann A, Ma'ayan A. KEA: kinase enrichment analysis. Bioinformatics 2009; 25: 684-686.
    • (2009) Bioinformatics , vol.25 , pp. 684-686
    • Lachmann, A.1    Ma'Ayan, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.