메뉴 건너뛰기




Volumn 279, Issue 1, 2012, Pages 91-99

Characterization of a hypertriglyceridemic transgenic miniature pig model expressing human apolipoprotein CIII

Author keywords

apolipoprotein CIII; hypertriglyceridemia; miniature pig; model; transgenic

Indexed keywords

APOLIPOPROTEIN C3; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; LIPOPROTEIN LIPASE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

EID: 83655161317     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08401.x     Document Type: Article
Times cited : (48)

References (30)
  • 1
    • 0033015655 scopus 로고    scopus 로고
    • Role of apoCs in lipoprotein metabolism: Functional differences between ApoC1, ApoC2, and ApoC3
    • Jong MC, Hofker MH, &, Havekes LM, (1999) Role of ApoCs in lipoprotein metabolism: functional differences between ApoC1, ApoC2, and ApoC3. Arterioscler Thromb Vasc Biol 19, 472-484. (Pubitemid 29135144)
    • (1999) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.19 , Issue.3 , pp. 472-484
    • Jong, M.C.1    Hofker, M.H.2    Havekes, L.M.3
  • 2
    • 0033991858 scopus 로고    scopus 로고
    • Molecular basis of exchangeable apolipoprotein function
    • Narayanaswami V, &, Ryan RO, (2000) Molecular basis of exchangeable apolipoprotein function. Biochim Biophys Acta 1483, 15-36.
    • (2000) Biochim Biophys Acta , vol.1483 , pp. 15-36
    • Narayanaswami, V.1    Ryan, R.O.2
  • 3
    • 0029018057 scopus 로고
    • Modulation of lipoprotein B binding to the LDL receptor by exogenous lipids and apolipoproteins CI, CII, CIII, and e
    • Clavey V, Lestavel-Delattre S, Copin C, Bard JM, &, Fruchart JC, (1995) Modulation of lipoprotein B binding to the LDL receptor by exogenous lipids and apolipoproteins CI, CII, CIII, and E. Arterioscler Thromb Vasc Biol 15, 963-971.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 963-971
    • Clavey, V.1    Lestavel-Delattre, S.2    Copin, C.3    Bard, J.M.4    Fruchart, J.C.5
  • 4
    • 0035081596 scopus 로고    scopus 로고
    • Transcriptional regulatory mechanisms of the human apolipoprotein genes in vitro and in vivo
    • DOI 10.1097/00041433-200104000-00012
    • Zannis VI, Kan HY, Kritis A, Zanni EE, &, Kardassis D, (2001) Transcriptional regulatory mechanisms of the human apolipoprotein genes in vitro and in vivo. Curr Opin Lipidol 12, 181-207. (Pubitemid 32242926)
    • (2001) Current Opinion in Lipidology , vol.12 , Issue.2 , pp. 181-207
    • Zannis, V.I.1    Kan, H.-Y.2    Kritis, A.3    Zanni, E.E.4    Kardassis, D.5
  • 5
    • 0034730752 scopus 로고    scopus 로고
    • A hormone response element in the human apolipoprotein CIII (apoCIII) enhancer is essential for intestinal expression of the apoAI and apoCIII genes and contributes to the hepatic expression of the two linked genes in transgenic mice
    • Kan H-Y, Georgopoulos S, &, Zannis V, (2000) A hormone response element in the human apolipoprotein CIII (apoCIII) enhancer is essential for intestinal expression of the apoAI and apoCIII genes and contributes to the hepatic expression of the two linked genes in transgenic mice. J Biol Chem 275, 30423-30431.
    • (2000) J Biol Chem , vol.275 , pp. 30423-30431
    • Kan, H.-Y.1    Georgopoulos, S.2    Zannis, V.3
  • 6
    • 0034672101 scopus 로고    scopus 로고
    • The SP1 sites of the human apoCIII enhancer are essential for the expression of the apoCIII gene and contribute to the hepatic and intestinal expression of the apoA-I gene in transgenic mice
    • Georgopoulos S, Kan HY, Reardon-Alulis C, &, Zannis V, (2000) The SP1 sites of the human apoCIII enhancer are essential for the expression of the apoCIII gene and contribute to the hepatic and intestinal expression of the apoAI gene in transgenic mice. Nucleic Acids Res 28, 4919-4929. (Pubitemid 32014262)
    • (2000) Nucleic Acids Research , vol.28 , Issue.24 , pp. 4919-4929
    • Georgopoulos, S.1    Kan, H.-Y.2    Reardon-Alulis, C.3    Zannis, V.4
  • 7
    • 0027480041 scopus 로고
    • Intestinal expression of the human apoA-I gene in transgenic mice is controlled by a DNA region 3' to the gene in the promoter of the adjacent convergently transcribed apoC-III gene
    • Walsh A, Azrolan N, Wang K, Marcigliano A, O'Connell A, &, Breslow JL, (1993) Intestinal expression of the human apoAI gene in transgenic mice is controlled by a DNA region 3′ to the gene in the promoter of the adjacent convergently transcribed apoCIII gene. J Lipid Res 34, 617-623. (Pubitemid 23118762)
    • (1993) Journal of Lipid Research , vol.34 , Issue.4 , pp. 617-623
    • Walsh, A.1    Azrolan, N.2    Wang, K.3    Marcigliano, A.4    O'Connell, A.5    Breslow, J.L.6
  • 8
    • 57649136395 scopus 로고    scopus 로고
    • The apolipoprotein CIII enhancer regulates both extensive histone modification and intergenic transcription of human apolipoprotein AI/CIII/AIV genes but not apolipoprotein AV
    • Li Y-J, Wei Y-S, &, Fu X-H, (2008) The apolipoprotein CIII enhancer regulates both extensive histone modification and intergenic transcription of human apolipoprotein AI/CIII/AIV genes but not apolipoprotein AV. J Biol Chem 283, 28436-28444.
    • (2008) J Biol Chem , vol.283 , pp. 28436-28444
    • Li, Y.-J.1    Wei, Y.-S.2    Fu, X.-H.3
  • 9
    • 0032562257 scopus 로고    scopus 로고
    • Triglyceride concentration and ischemic heart disease: An eight-year follow-up in the Copenhagen Male Study
    • Jeppesen J, Hein HO, Suadicani P, &, Gyntelberg F, (1998) Triglyceride concentration and ischemic heart disease: an eight-year follow-up in the Copenhagen Male Study. Circulation 97, 1029-1036.
    • (1998) Circulation , vol.97 , pp. 1029-1036
    • Jeppesen, J.1    Hein, H.O.2    Suadicani, P.3    Gyntelberg, F.4
  • 10
    • 0032080923 scopus 로고    scopus 로고
    • Normal triglyceride levels and coronary artery disease events: The Baltimore coronary observational long-term study
    • PII S0735109798000837
    • Miller M, Seidler A, Moalemi A, &, Pearson TA, (1998) Normal triglyceride levels and coronary artery disease events: the Baltimore Coronary Observational Long-Term Study. J Am Coll Cardiol 31, 1252-1257. (Pubitemid 128713120)
    • (1998) Journal of the American College of Cardiology , vol.31 , Issue.6 , pp. 1252-1257
    • Miller, M.1    Seidler, A.2    Moalemi, A.3    Pearson, T.A.4
  • 11
    • 0029884921 scopus 로고    scopus 로고
    • Hypertriglyceridemia and elevated lipoprotein(a) are risk factors for major coronary events in middle-aged men
    • DOI 10.1016/S0002-9149(96)00159-2
    • Assmann G, Schulte H, &, von Eckardstein A, (1996) Hypertriglyceridemia and elevated levels of lipoprotein(a) are risk factors for major coronary events in middle-aged men. Am J Cardiol 77, 1179-1184. (Pubitemid 26186958)
    • (1996) American Journal of Cardiology , vol.77 , Issue.14 , pp. 1179-1184
    • Assmann, G.1    Schulte, H.2    Von Eckardstein, A.3
  • 13
    • 4043134745 scopus 로고    scopus 로고
    • Rate of production of plasma and Very-Low-Density Lipoprotein (VLDL) apolipoprotein C-III is strongly related to the concentration and level of production of VLDL triglyceride in male subjects with different body weights and levels of insulin sensitivity
    • DOI 10.1210/jc.2003-032056
    • Cohn JS, Patterson BW, Uffelman KD, Davignon J, &, Steiner G, (2004) Rate of production of plasma and very-low-density lipoprotein (VLDL) apolipoprotein C-III is strongly related to the concentration and level of production of VLDL triglyceride in male subjects with different body weights and levels of insulin sensitivity. J Clin Endocrinol Metab 89, 3949-3955. (Pubitemid 39071498)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.8 , pp. 3949-3955
    • Cohn, J.S.1    Patterson, B.W.2    Uffelman, K.D.3    Davignon, J.4    Steiner, G.5
  • 15
    • 0025030698 scopus 로고
    • Hypertriglyceridemia as a result of human apoCIII gene expression in transgenic mice
    • Ito Y, Azrolan N, O'Connell A, Walsh A, &, Breslow JL, (1990) Hypertriglyceridemia as a result of human apoCIII gene expression in transgenic mice. Science 249, 790-793.
    • (1990) Science , vol.249 , pp. 790-793
    • Ito, Y.1    Azrolan, N.2    O'Connell, A.3    Walsh, A.4    Breslow, J.L.5
  • 17
    • 0016795172 scopus 로고
    • Swine lipoproteins and atherosclerosis. Changes in the plasma lipoproteins and apoproteins induced by cholesterol feeding
    • Mahley RW, Weisgraber KH, Innerarity T, Brewer HB Jr, &, Assmann G, (1975) Swine lipoproteins and atherosclerosis. Changes in the plasma lipoproteins and apoproteins induced by cholesterol feeding. Biochemistry 14, 2817-2823.
    • (1975) Biochemistry , vol.14 , pp. 2817-2823
    • Mahley, R.W.1    Weisgraber, K.H.2    Innerarity, T.3    Brewer, Jr.H.B.4    Assmann, G.5
  • 18
    • 0015356172 scopus 로고
    • Of pigs and men and research: A review of applications and analogies of the pig, Sus scrofa, in human medical research
    • Douglas WR, (1972) Of pigs and men and research: a review of applications and analogies of the pig, Sus scrofa, in human medical research. Space Life Sci 3, 226-234.
    • (1972) Space Life Sci , vol.3 , pp. 226-234
    • Douglas, W.R.1
  • 19
    • 0002780662 scopus 로고
    • Swine as animal models in cardiovascular research
    • In (Tumbleson M.E. ed.), Plenum Press, NY
    • Lee KT, (1986) Swine as animal models in cardiovascular research. In Swine in Biomedical Research (, Tumbleson ME, ed.), pp. 1481-1496. Plenum Press, NY.
    • (1986) Swine in Biomedical Research , pp. 1481-1496
    • Lee, K.T.1
  • 20
    • 0001566857 scopus 로고
    • The pig as a model for myocardial ischemia
    • In (Tumbleson M.E. ed.), Plenum Press, NY
    • White FC, &, Bloor CM, (1986) The pig as a model for myocardial ischemia. In Swine in Biomedical Research (, Tumbleson ME, ed.), pp. 481-490. Plenum Press, NY.
    • (1986) Swine in Biomedical Research , pp. 481-490
    • White, F.C.1    Bloor, C.M.2
  • 21
    • 0001354623 scopus 로고
    • Function and development of coronary collateral vessels
    • In (Schaper W. & Schaper J. eds), Kluwer Academic Publishers, Boston
    • Longhurst JC, &, Symons JD, (1993) Function and development of coronary collateral vessels. In Collateral Circulation (, Schaper W, &, Schaper J, eds), pp. 195-214. Kluwer Academic Publishers, Boston.
    • (1993) Collateral Circulation , pp. 195-214
    • Longhurst, J.C.1    Symons, J.D.2
  • 22
    • 64549097708 scopus 로고    scopus 로고
    • Plasma apolipoprotein CI and CIII levels are associated with increased plasma triglyceride levels and decreased fat mass in men with the metabolic syndrome
    • Van der Ham RLM, Dehnavi RA, Berbée JFP, Putter H, de Roos A, Romijn JA, Rensen PCN, &, Tamsma JT, (2009) Plasma apolipoprotein CI and CIII levels are associated with increased plasma triglyceride levels and decreased fat mass in men with the metabolic syndrome. Diabetes Care 32, 184-186.
    • (2009) Diabetes Care , vol.32 , pp. 184-186
    • Van Der Ham, R.L.M.1    Dehnavi, R.A.2    Berbée, J.F.P.3    Putter, H.4    De Roos, A.5    Romijn, J.A.6    Rensen, P.C.N.7    Tamsma, J.T.8
  • 23
    • 10044297104 scopus 로고    scopus 로고
    • Nuclear remodeling and reprogramming in transgenic pig production
    • Prather RS, Sutovsky P, &, Green JA, (2004) Nuclear remodeling and reprogramming in transgenic pig production. Exp Biol Med 229, 1120-1126. (Pubitemid 39602254)
    • (2004) Experimental Biology and Medicine , vol.229 , Issue.11 , pp. 1120-1126
    • Prather, R.S.1    Sutovsky, P.2    Green, J.A.3
  • 24
    • 79960442664 scopus 로고    scopus 로고
    • Hypertriglyceridemia and delayed clearance of fat load in transgenic rabbits expressing human apolipoprotein CIII
    • Ding Y, Wang Y, Zhu H, Fan J, Yu L, Liu G, &, Liu E, (2011) Hypertriglyceridemia and delayed clearance of fat load in transgenic rabbits expressing human apolipoprotein CIII. Transgenic Res 20, 867-875.
    • (2011) Transgenic Res , vol.20 , pp. 867-875
    • Ding, Y.1    Wang, Y.2    Zhu, H.3    Fan, J.4    Yu, L.5    Liu, G.6    Liu, E.7
  • 25
    • 0026443622 scopus 로고
    • Mechanism of hypertriglyceridemia in human apolipoprotein (Apo) CIII transgenic mice diminished very low density lipoprotein fractional catabolic rate associated with increased Apo CIII and reduced Apo e on the particles
    • Aalto-Setälä K, Fisher E, Chen X, Chajek-Shaul T, Hayek T, Zechner R, Walsh A, Ramakrishnan R, Ginsberg HN, &, Breslow JL, (1992) Mechanism of hypertriglyceridemia in human apolipoprotein (Apo) CIII transgenic mice diminished very low density lipoprotein fractional catabolic rate associated with increased Apo CIII and reduced Apo E on the particles. J Clin Invest 90, 1889-1900.
    • (1992) J Clin Invest , vol.90 , pp. 1889-1900
    • Aalto-Setälä, K.1    Fisher, E.2    Chen, X.3    Chajek-Shaul, T.4    Hayek, T.5    Zechner, R.6    Walsh, A.7    Ramakrishnan, R.8    Ginsberg, H.N.9    Breslow, J.L.10
  • 27
    • 77949642952 scopus 로고    scopus 로고
    • Influence of exercise and perivascular adipose tissue on coronary artery vasomotor function in a familial hypercholesterolemic porcine atherosclerosis model
    • Bunker AK, &, Laughlin MH, (2010) Influence of exercise and perivascular adipose tissue on coronary artery vasomotor function in a familial hypercholesterolemic porcine atherosclerosis model. J Appl Physiol 108, 490-497.
    • (2010) J Appl Physiol , vol.108 , pp. 490-497
    • Bunker, A.K.1    Laughlin, M.H.2
  • 28
    • 0347418928 scopus 로고    scopus 로고
    • Production of Cloned Pigs by Using Somatic Cells as Donors
    • Lai L, &, Prather RS, (2003) Production of cloned pigs by using somatic cells as donors. Cloning Stem Cells 5, 233-241. (Pubitemid 38031849)
    • (2003) Cloning and Stem Cells , vol.5 , Issue.4 , pp. 233-241
    • Lai, L.1    Prather, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.