Combined α7 nicotinic acetylcholine receptor agonism and partial serotonin transporter inhibition produce antidepressant-like effects in the mouse forced swim and tail suspension tests: A comparison of SSR180711 and PNU-282987

Pharmacology Biochemistry and Behavior

Volumn 100, Issue 3, 2012, Pages 624-629

  Andreasen, Jesper T ^a   Redrobe, John P ^b   Nielsen, Elsebet Ø ^c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b H LUNDBECK A S   (Denmark)

^c NEUROSEARCH A S   (Denmark)

Author keywords

7 nicotinic acetylcholine receptor; Antidepressant; Mouse forced swim test; Mouse tail suspension test; Serotonin reuptake inhibition

Indexed keywords

1,4 DIAZABICYCLO[3.2.2]NONANE 4 CARBOXYLIC ACID 4 BROMOPHENYL ESTER; 4 CHLORO N (3 QUINUCLIDINYL)BENZAMIDE; ALPHA BUNGAROTOXIN; CITALOPRAM; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA 7; SEROTONIN; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; FEMALE; FORCED SWIMMING TEST; LOCOMOTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; BENZAMIDES; BICYCLO COMPOUNDS; BICYCLO COMPOUNDS, HETEROCYCLIC; CEREBRAL CORTEX; CITALOPRAM; DEPRESSION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; FEMALE; MICE; MICE, INBRED STRAINS; MOLECULAR TARGETED THERAPY; NICOTINIC AGONISTS; RECEPTORS, NICOTINIC; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS; TISSUE DISTRIBUTION;

RATTUS; RODENTIA;

EID: 83555177201     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2011.11.004     Document Type: Article

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