Different pharmacokinetics of nicotine following intravenous administration of nicotine base and nicotine hydrogen tartarate in rats

Journal of Controlled Release

Volumn 77, Issue 3, 2001, Pages 183-190

  Hwa Jung, Byung ^a,b   Chul Chung, Bong ^b   Chung, Suk Jae ^a   Shim, Chang Koo ^a  

^a Seoul National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

Author keywords

Cotinine; Nicotine; Nicotine base; Nicotine hydrogen tartarate; Pharmacokinetics

Indexed keywords

COTININE; NICOTINE; NICOTINE TARTRATE;

AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; BLOOD CELL; CLEARANCE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG METABOLISM; MALE; MEAN RESIDENCE TIME; NONHUMAN; PARTICLE SIZE; PARTITION COEFFICIENT; PLASMA HALF LIFE; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; RAT; STEADY STATE;

ANIMALS; BLOOD PROTEINS; INJECTIONS, INTRAVENOUS; MALE; NICOTINE; NICOTINIC AGONISTS; PARTICLE SIZE; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; TARTRATES;

EID: 0035856770     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00452-7     Document Type: Article

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