α7 nicotinic receptor subunit is present on serotonin neurons projecting to hippocampus and septum

Synapse

Volumn 55, Issue 3, 2005, Pages 196-200

  Aznar, Susana ^a   Kostova, Viktorija ^a   Christiansen, Søren H ^a   Knudsen, Gitte M ^a  

^a Mental Health Services CPH   (Denmark)

Author keywords

Acetylcholine; Alzheimer; Depression; FluoroGold; Nicotinic receptor; Retrobeads; Serotonin

Indexed keywords

ALPHA BUNGAROTOXIN; BUNGAROTOXIN RECEPTOR; NEUROTRANSMITTER; NICOTINE; NICOTINIC RECEPTOR; PRESYNAPTIC RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; DIAGONAL BAND OF BROCA; FLUORESCENCE; HIPPOCAMPUS; HIPPOCAMPUS POTENTIAL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; NERVE PROJECTION; NONHUMAN; PRIORITY JOURNAL; SEPTUM PELLUCIDUM; SEROTONINERGIC NERVE CELL;

ANIMALS; AXONAL TRANSPORT; BINDING, COMPETITIVE; BUNGAROTOXINS; DIAGONAL BAND OF BROCA; EFFERENT PATHWAYS; FLUORESCENT ANTIBODY TECHNIQUE; HIPPOCAMPUS; HYDRAZINES; MICROSPHERES; NEURONS; PRESYNAPTIC TERMINALS; PROTEIN SUBUNITS; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; SEPTUM OF BRAIN; SEROTONIN; STILBAMIDINES; SYNAPTIC TRANSMISSION;

EID: 13244291545     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.20108     Document Type: Article

References (20)

1. Aznar S, Qian ZX, Knudsen GM. 2004. Non-serotonergic dorsal and median raphe projection onto parvalbumin- and calbindin-containing neurons in hippocampus and septum. Neuroscience 124:573-581.
2. Bitner RS, Nikkel AL. 2002. Alpha-7 nicotinic receptor expression by two distinct cell types in the dorsal raphe nucleus and locus coeruleus of rat. Brain Res 938:45-54.
3. Clements JR, Madl JE, Johnson RL, Larson AA, Beitz AJ. 1987. Localization of glutamate, glutaminase, aspartate and aspartate aminotransferase in the rat midbrain periaqueductal gray. Exp Brain Res 67:594-602.
4. Cucchiaro G, Commons KG. 2003. Alpha 4 nicotinic acetylcholine receptor subunit links cholinergic to brainstem monoaminergic neurotransmission. Synapse 49:195-205.
5. Dineley KT, Westerman M, Bui D, Bell K, Ashe KH, Sweatt JD. 2001. Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: in vitro and in vivo mechanisms related to Alzheimer's disease. J Neurosci 21:4125-4133.
6. Fabian-Fine R, Skehel P, Errington ML, Davies HA, Sher E, Stewart MG, Fine A. 2001. Ultrastructural distribution of the alpha7 nicotinic acetylcholine receptor subunit in rat hippocampus. J Neurosci 21:7993-8003.
7. Freund TF. 1992. GABAergic septal and serotonergic median raphe afferents preferentially innervate inhibitory interneurons in the hippocampus and dentate gyrus. Epilepsy Res Suppl 7:79-91.
8. Freund TF, Antal M. 1988. GABA-containing neurons in the septum control inhibitory interneurons in the hippocampus. Nature 336:170-173.
9. Freund TF, Gulyas AI, Acsady L, Gorcs T, Toth K. 1990. Serotonergic control of the hippocampus via local inhibitory interneurons. Proc Natl Acad Sci U S A 87:8501-8505.
10. Kenny PJ, File SE, Neal MJ. 2000. Evidence for a complex influence of nicotinic acetylcholine receptors on hippocampal serotonin release. J Neurochem 75:2409-2414.
11. Leranth C, Vertes RP. 1999. Median raphe serotonergic innervation of medial septum/diagonal band of broca (MSDB) parvalbumin-containing neurons: possible involvement of the MSDB in the desynchronization of the hippocampal EEG. J Comp Neurol 410:586-598.
12. Levin ED, Bettegowda C, Blosser J, Gordon J. 1999. AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats. Behav Pharmacol 10:675-680.
13. Li X, Rainnie DG, McCarley RW, Greene RW. 1998. Presynaptic nicotinic receptors facilitate monoaminergic transmission. J Neurosci 18:1904-1912.
14. Mihailescu S, Palomero-Rivero M, Meade-Huerta P, Maza-Flores A, Drucker-Colin R. 1998. Effects of nicotine and mecamylamine on rat dorsal raphe neurons. Eur J Pharmacol 360:31-36.
15. Palmer AM. 1996. Neurochemical studies of Alzheimer's disease. Neurodegeneration 5:381-391.
16. Paxinos G, Watson C. 1998. The rat brain in stereotaxic coordinates. San Diego: Academic Press.
17. Seth P, Cheeta S, Tucci S, File SE. 2002. Nicotinic-serotonergic interactions in brain and behaviour. Pharmacol Biochem Behav 71:795-805.
18. Teaktong T, Graham A, Court J, Perry R, Jaros E, Johnson M, Hall R, Perry E. 2003. Alzheimer's disease is associated with a selective increase in alpha7 nicotinic acetylcholine receptor immunoreactivity in astrocytes. Glia 41:207-211.
19. Toth K, Borhegyi Z, Freund TF. 1993. Postsynaptic targets of GABAergic hippocampal neurons in the medial septum-diagonal band of Broca complex. J Neurosci 13:3712-3724.
20. Wang HY, Lee DH, Davis CB, Shank RP. 2000. Amyloid peptide Abeta(1-42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors. J Neurochem 75:1155-1161.