Modulation of cytochrome P450 and induction of DNA damage in Cyprinus carpio exposed in situ to surface water treated with chlorine or alternative disinfectants in different seasons

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 729, Issue 1-2, 2012, Pages 81-89

  Canistro, Donatella ^a   Melega, Simone ^a   Ranieri, Dario ^a   Sapone, Andrea ^a   Gustavino, Bianca ^b   Monfrinotti, Monica ^b   Rizzoni, Marco ^b   Paolini, Moreno ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Cancer; Cyprinus carpio; Cytochrome P450; Disinfection by products; Drinking water; Micronucleus

Indexed keywords

16ALPHA HYDROXYTESTOSTERONE; 16BETA HYDROXYTESTOSTERONE; 2ALPHA HYDROXYTESTOSTERONE; 2BETA HYDROXYTESTOSTERONE; 4 NITROPHENOL; 4 NITROPHENOL HYDROXYLASE; 6ALPHA HYDROXYTESTOSTERONE; 6BETA HYDROXYTESTOSTERONE; 7ALPHA HYDROXYTESTOSTERONE; AMINOPYRINE N DEMETHYLASE; ANDROSTENEDIONE; CHLORINE; CHLORINE DIOXIDE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; CYTOCHROME P450 3A1; CYTOCHROME P450 3A2; DISINFECTANT AGENT; DNA; DRINKING WATER; ETHOXYRESORUFIN DEETHYLASE; HYPOCHLORITE SODIUM; METHOXYRESORUFIN O DEMETHYLASE; PENTOXYRESORUFIN DEALKYLASE; PERACETIC ACID; SURFACE WATER; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER RISK; CARP; CONTROLLED STUDY; DEALKYLATION; DNA DAMAGE; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME REGULATION; ERYTHROCYTE; EXPOSURE; GENOTOXICITY; HEALTH HAZARD; HYDROXYLATION; MICRONUCLEUS TEST; NONHUMAN; PRIORITY JOURNAL; SUMMER; URINARY TRACT CANCER; WATER TREATMENT; WINTER;

ANIMALS; CARPS; CHLORINE COMPOUNDS; COMET ASSAY; CYTOCHROME P-450 ENZYME SYSTEM; DISINFECTANTS; DNA DAMAGE; DRINKING WATER; ENVIRONMENTAL MONITORING; MODELS, ANIMAL; NITROPHENOLS; OXIDES; PERACETIC ACID; SEASONS; SODIUM HYPOCHLORITE; WATER POLLUTANTS, CHEMICAL;

ANIMALIA; CYPRINUS CARPIO;

EID: 83555174550     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2011.09.008     Document Type: Article

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