Perturbation of cytochrome P450, generation of oxidative stress and induction of DNA damage in Cyprinus carpio exposed in situ to potable surface water

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 626, Issue 1-2, 2007, Pages 143-154

  Sapone, Andrea ^a   Gustavino, Bianca ^b   Monfrinotti, Monica ^b   Canistro, Donatella ^a   Broccoli, Massimiliano ^a   Pozzetti, Laura ^a   Affatato, Alessandra ^a   Valgimigli, Luca ^a   Forti, Giorgio Cantelli ^a   Pedulli, Gian Franco ^a   Biagi, Gian Luigi ^a   Abdel Rahman, Sherif Z ^c   Paolini, Moreno ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Cancer; Cyprinus carpio; Cytochrome p450; Drinking water by products; Micronucleus; Organochlorine by products; ROS

Indexed keywords

CHLORINE DIOXIDE; CYTOCHROME P450; DISINFECTANT AGENT; HYPOCHLORITE SODIUM; PERACETIC ACID; REACTIVE OXYGEN METABOLITE; SURFACE WATER; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARP; CONTROLLED STUDY; DNA DAMAGE; ELECTRON SPIN RESONANCE; ERYTHROCYTE; FEMALE; GENETIC DAMAGE; ITALY; MALE; MICRONUCLEUS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; CARPS; CHLORINE COMPOUNDS; CYTOCHROME P-450 ENZYME SYSTEM; DNA DAMAGE; ELECTRON SPIN RESONANCE SPECTROSCOPY; LIVER; MALE; OXIDATIVE STRESS; OXIDES; SODIUM HYPOCHLORITE; WATER SUPPLY;

CYPRINUS CARPIO;

EID: 33845329156     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2006.09.010     Document Type: Article

References (54)

1. World Health Organization. Revision of the WHO Guidelines for Drinking Water Quality (1996), WHO, Geneva, Switzerland
2. Rook J.J. Formation of haloforms during chlorination of natural waters. J. Water Treat. Exam. 23 (1974) 234-243
3. Cantor K.T. Drinking water and cancer. Cancer Causes Control 8 (1997) 292-308
4. Boorman G.A. Drinking water disinfection by-products: review and approach to toxicity evaluation. Environ. Health Perspect. 107 (1999) 207-217
5. Pereira M.A. Carcinogenic activity of dichloroacetic acid and trichloroacetic acid in the liver of female B6C3F1 mice. Fund. Appl. Toxicol. 31 (1996) 192-199
6. IARC. Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide. Proceedings of the IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, France, February 17-24, 1998. IARC Monogr. Eval. Carcinogen. Risks Hum. 71 Pt 1 (1999) 1-315
7. Meier J.R., Ringhand H.P., Coleman W.E., Schenck K.M., Munch J.W., Streicher R.P., Kaylor W.H., and Kopfler F.C. Mutagenic by-products from chlorination of humic acid. Environ. Health Perpect. 69 (1986) 101-107
8. Hutchinson T.H., Jha A.N., Mackay J.M., Elliot B.M., and Dixon D.R. Assessment of developmental effects, cytotoxicity and genotoxicity in the marine polychaete (Platinereis dumerilii) exposed to disinfected municipal sewage effluents. Mutat. Res. 399 (1998) 97-108
9. Minissi S., Ciccotti E., and Rizzoni M. Micronucleus test in erythrocytes of Barbus plebenius (Teleostei, Pisces) from two natural environments: a bioassay for the in situ detection of mutagens in freshwater. Mutat. Res. 367 (1996) 245-251
10. Gustavino B., Scornajenghi K.A., Minissi S., and Ciccotti E. Micronuclei induced in erythrocytes of Ciprinus carpio by X-rays and colchicine. Mutat. Res. 494 (2001) 151-159
11. Itoh S., Ikeda D., Toba Y., and Sumitomo H. Changes of activity inducing chromosomal aberrations and transformations of chlorinated humic acids. Water Res. 35 (2001) 2621-2628
12. Woodruff N.H., Durant J.L., Donhoffner L.L., Penman B.W., and Crespi C.L. Human cell mutagenicity of chlorinated and unchlorinated water and the disinfection by-products. Mutat. Res. 495 (2001) 157-168
13. Soffritti M., Belpoggi F., Lenzi A., and Maltoni C. Results of long-term carcinogenicity studies of chlorine in rats. Ann. NY Acad. Sci. 26 (1997) 189-208
14. Koivusalo M., Pukkala E., Vartiainen T., Jaakkola J.J., and Hakulinen T. Drinking water chlorination and cancer-a historical cohort study in Finland. Cancer Causes Control 8 (1997) 192-200
15. Steffensen I.L., Paulsen J.E., Engeset D., Kronberg L., and Alexander J. The drinking water chlorination by-products 3,4-dichloro-5-hydroxy-2[5H]-furanone (mucochloric acid) and 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone do not induce preneoplastic or neoplastic intestinal lesions in F344 rats, Balb/ca mice or C57bl/6J-min mice. Pharmacol. Toxicol. 85 (1999) 56-64
16. Klotz J.B., and Pyrch L.A. Neural tube defects and drinking water disinfection by-products. Epidemiology 10 (1999) 383-390
17. Maki-Paakkanen J., Komulainen H., and Kronberg L. Bacterial and mammalian-cell genotoxicity of mixtures of chlorohydroxyfuranones, by-products of water chlorination. Environ. Mol. Mutagen. 43 (2004) 217-225
18. Hooth M.J., McDorman K.S., Hester S.D., George M.H., Brooks L.R., Swank A.E., and Wolf D.C. The carcinogenic response of Tsc2 mutant Long-Evans (Eker) rats to a mixture of drinking water disinfection by-products was less than additive. Toxicol. Sci. 69 (2002) 322-331
19. McDorman K.S., Hooth M.J., Starr T.B., and Wolf D.C. Analysis of preneoplastic and neoplastic renal lesions in Tsc2 mutant Long-Evans (Eker) rats following exposure to a mixture of drinking water disinfection by-products. Toxicology 187 (2003) 1-12
20. Komulainen H. Experimental cancer studies of chlorinated by-products. Toxicology 198 (2004) 239-248
21. Baldry M.G.C., French M.S., and Slater D. The activity of peracetic acid on sewage indicator bacteria and viruses. Water Sci. Technol. 24 (1991) 353-357
22. Baldry M.G.C., Cavadore A., French M.S., Massa G., Rodrigues M.L., Schirch P.F.T., and Threadgold T.L. Effluent disinfection in warm climates with peracetic acid. Water Sci. Technol. 31 (1995) 161-164
23. Lefevre F., Audic J.M., and Verrand F. Peracetic acid disinfection of secondary effluents discharged off coastal sea water. Water Sci. Technol. 25 (1992) 155-164
24. Monarca S., Richardson S.D., Feretti D., Grottolo M., Thruston A.D., Zani C., Navazio G., Ragazzo P., Zerbini I., and Alberti A. Mutagenicity and disinfection by-products in surface drinking water disinfected with peracetic acid. Environ. Toxicol. Chem. 21 (2002) 309-318
25. Kitis M. Disinfection of wastewater with peracetic acid: a review. Environ. Int. 30 1 (2004) 47-55
26. Paolini M., Biagi G.L., Cantelli-Forti G., and Bauer C. Further mechanisms of non-genotoxic carcinogenesis. Trends Pharmacol. Sci. 15 (1994) 322-323
27. Paolini M., Cantelli-Forti G., Perocco P., Pedulli G.F., Abdel-Rahman S.Z., and Legator M.S. Co-carcinogenic effect of beta-carotene. Nature 398 (1999) 760-761
28. Butterworth B.E. Consideration of both genotoxic and nongenotoxic mechanisms in predicting carcinogenic potential. Mutat. Res. 239 (1990) 117-132
29. Poulsen H.E., and Loft S. Early biochemical markers of effects: enzyme induction, oncogene activation and markers of oxidative damage. Toxicology 101 (1995) 55-64
30. Ames B.N., Gold L.S., and Willett W.C. The causes and prevention of cancer. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 5258-5265
31. Klaunig J.E., Xu Y., Isenberg J.S., Bachowski S., Kolaja K.L., Jiang J., Stevenson D.E., and Alborg Jr. E.F. The role of oxidative stress in chemical carcinogenesis. Environ. Health Perspect. 106 Suppl. 1 (1998) 289-295
32. Kinoshita A., Wanibuchi H., Imaoka S., Ogawa M., Masuda C., Morimura K., Funae Y., and Fukushima S. Formation of 8-hydroxydeoxyguanosine and cell-cycle arrest in the rat liver via generation of oxidative stress by phenobarbital: association with expression profiles of p21(WAF1/Cip1), cyclin D1 and Ogg1. Carcinogenesis 23 (2002) 341-349
33. Bauer C., Corsi C., and Paolini M. Stability of microsomal monooxygenases in murine liver S9 fractions derived from phenobarbital and β-naphthoflavone induced animals under various long-term conditions of storage. Teratogen. Carcinogen. Mutagen. 14 (1994) 13-22
34. Mazel P. Fundamentals of Drug Metabolism and Drug Disposition (1971), Wiliams and Wilkins, Baltimore pp. 546-550
35. Nash T. Colorimetric estimation of formaldehyde by means of Hantzsch reaction. Biochem. J. 55 (1953) 416-421
36. Reinke L.A., and Mayer M.J. p-Nitrophenol hydroxylation. A microsomal oxidation which is highly inducible by ethanol. Drugs Metab. Dispos. 13 (1985) 548-552
37. Lubet R.A., Mayer M.J., Cameron J.W., Raymond W.N., Burke M., Wolf T., and Guengerich F.P. Dealkylation of pentoxyresorufin. A rapid and sensitive assay for measuring induction of cytochrome(s) P450 by phenobarbital and other xenobiotics in rat. Arch. Biochem. Biophys. 238 (1985) 43-48
38. Burke M.D., Thompson S., Elcombe C.R., Halpert J., Haaparant T., and Meyer R.T. Ethoxy-, pentoxy- and benzyloxy-phenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P450. Biochem. Pharmacol. 34 (1985) 3337-3345
39. Van der Hoeven T.H. Assay of hepatic microsomal testosterone hydroxylases by high-performance liquid chromatography. Anal. Biochem. 138 (1984) 57-65
40. Lowry O.H., Rosenbrough H.J., Farr A.L., and Randall R.J. Protein measurement with Folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
41. Bailey Y.L. Techniques in Protein Chemistry (1967), Elsevier, Amsterdam pp. 340-341
42. Valgimigli L., Pedulli G.F., and Paolini M. Measurement of oxidative stress by EPR radical-probe technique. Free Radic. Biol. Med. 31 (2001) 708-716
43. Gustavino B., Buschini A., Monfrinotti M., Rizzoni M., Tancioni L., Poli P., and Rossi C. Modulating effects of humic acids on genotoxicity induced by water disinfectants in Cyprinus carpio. Mutat. Res. 587 (2005) 103-113
44. Box G.P., and Hunter W.G. Statistics for Experiments (1978), Wiley, New York pp. 80-82
45. Das R.K., and Nanda N.K. Induction of micronuclei in peripheral erythrocytes of fish Heteropneustes fossilis bymitomycin C and paper mill effluent. Mutat. Res. 175 (1986) 67-71
46. Al-Sabti K. Micronuclei induced by selenium, mercury, methylmercury and their mixtures in binucleated blocked fish erythrocyte cells. Mutat. Res. 320 (1994) 157-163
47. Gillette J.R., Brodie B., and Ladu B.N. The oxidation of drugs by liver microsomes: on the role of TPNH and oxygen. J. Pharmacol. Exp. Ther. 119 (1957) 532-540
48. Paolini M., Pozzetti L., Pedulli G., Cipollone M., Mesirca R., and Cantelli-Forti G. Paramagnetic resonance in detecting carcinogenic risk from cytochrome P450 overexpression. J. Invest. Med. 44 (1996) 470-473
49. Puntarulo S., and Cederbaum A.I. Production of reactive oxygen species by microsomes enriched in specific human cytochrome P450 enxymes. Free Radic. Biol. Med. 24 (1998) 1324-1330
50. Valgimigli L., Pedulli G., and Paolini M. Measurement of oxidative stress by EPR radical-probe technique. Free Radic. Biol. Med. 31 (2001) 708-716
51. Al-Sabti K., Franko M., Andrijanič B., Knez S., and Stegnar P. Chromium induced micronuclei in fish. J. Appl. Toxicol. 14 (1994) 333-336
52. Paolini M., Barillari J., Trespidi S., Valgimigli L., Pedulli G.F., and Cantelli-Forti G. Captan impairs CYP-catalyzed drug metabolism in the mouse. Chem. Biol. Interact. 123 (1999) 149-170
53. Paolini M., Antelli A., Pozzetti L., Spetlova D., Perocco P., Valgimigli L., Pedulli G.F., and Cantelli-Forti G. Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene supplemented rats. Carcinogenesis 22 (2001) 1483-1495
54. Buschini A., Martino A., Gustavino B., Monfrinotti M., Poli P., Rossi C., Santoro M., Dörr A.J.M., and Rizzoni M. Comet assay and micronucleus test in circulating erythrocytes of Cyprinus carpio specimens exposed in situ to lake waters treated with disinfectants for potabilization. Mutat. Res. 557 (2004) 119-129