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Volumn 24, Issue 6, 2011, Pages 1153-1168

Cyto- and genotoxicity of a vanadyl(IV) complex with oxodiacetate in human colon adenocarcinoma (Caco-2) cells: Potential use in cancer therapy

Author keywords

Caco 2 tumoral cells; Cytotoxicity; Genotoxicity; Multidentate ligands; Vanadyl(IV) cation

Indexed keywords

ACETIC ACID DERIVATIVE; FREE RADICAL; GLUTATHIONE; OXODIACETATE; PLASMID DNA; SCAVENGER; UNCLASSIFIED DRUG; VANADYL DERIVATIVE;

EID: 83555173420     PISSN: 09660844     EISSN: 15728773     Source Type: Journal    
DOI: 10.1007/s10534-011-9474-x     Document Type: Article
Times cited : (13)

References (65)
  • 1
    • 0032796936 scopus 로고    scopus 로고
    • 5) in male mice. II. Effects in several mouse tissues
    • DOI 10.1002/(SICI)1520-6866(1999)19:4<243::AID-TCM1>3.0.CO;2-J
    • M Altamirano-Lozano M Valverde L Alvarez-Barrera B Molina E Rojas 1999 Reprotoxic and genotoxic studies of vanadium pentoxide (V2)O(5) in male mice. II. Effects in several mouse tissues Teratog Carcinog Mutagen 19 243 255 10406888 10.1002/(SICI)1520-6866(1999)19:4<243::AID-TCM1>3.0.CO;2-J 1:CAS:528:DyaK1MXks12qt7w%3D (Pubitemid 29337090)
    • (1999) Teratogenesis Carcinogenesis and Mutagenesis , vol.19 , Issue.4 , pp. 243-255
    • Altamirano-Lozano, M.1    Valverde, M.2    Alvarez-Barrera, L.3    Molina, B.4    Rojas, E.5
  • 2
    • 0033048549 scopus 로고    scopus 로고
    • Molecular genotoxicity profiles of apoptosis-inducing vanadocene complexes
    • DOI 10.1006/taap.1998.8592
    • J Aubrecht RK Narla P Ghosh J Stanek FM Uckun 1999 Molecular genotoxicity profiles of apoptosis-inducing vanadocene complexes Toxicol Appl Pharmacol 154 228 235 9931282 10.1006/taap.1998.8592 1:CAS:528:DyaK1MXhtlOksbY%3D (Pubitemid 29085234)
    • (1999) Toxicology and Applied Pharmacology , vol.154 , Issue.3 , pp. 228-235
    • Aubrecht, J.1    Narla, R.K.2    Ghosh, P.3    Stanek, J.4    Uckun, F.M.5
  • 4
    • 0038288752 scopus 로고    scopus 로고
    • Synthesis of a new vanadyl(IV) complex with trehalose (TreVO): Insulin-mimetic activities in osteoblast-like cells in culture
    • DA Barrio PAM Williams AM Cortizo SB Etcheverry 2003 Synthesis of a new vanadyl(IV) complex with trehalose (TreVO): insulin-mimetic activities in osteoblast-like cells in culture J Biol Inorg Chem 8 459 468 12761667 1:CAS:528:DC%2BD3sXjvFCjsbY%3D (Pubitemid 36578197)
    • (2003) Journal of Biological Inorganic Chemistry , vol.8 , Issue.4 , pp. 459-468
    • Barrio, D.A.1    Williams, P.A.M.2    Cortizo, A.M.3    Etcheverry, S.B.4
  • 5
    • 0024443493 scopus 로고
    • 5, as an efficient reagent for the oxidative cleavage of DNA
    • 5, as an efficient reagent for the oxidative cleavage of DNA Biochemistry 28 7268 7275 2819067 10.1021/bi00444a019 1:CAS:528:DyaL1MXltFWktLs%3D (Pubitemid 19227367)
    • (1989) Biochemistry , vol.28 , Issue.18 , pp. 7268-7275
    • Bernadou, J.1    Pratviel, G.2    Bennis, F.3    Girardet, M.4    Meunier, B.5
  • 6
    • 0032618361 scopus 로고    scopus 로고
    • Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis
    • 10451030 1:CAS:528:DyaK1MXltVKmtrc%3D
    • A Bishayee S Roy M Chatterjee 1999 Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis Oncol Res 11 41 53 10451030 1:CAS:528:DyaK1MXltVKmtrc%3D
    • (1999) Oncol Res , vol.11 , pp. 41-53
    • Bishayee, A.1    Roy, S.2    Chatterjee, M.3
  • 7
    • 0022391554 scopus 로고
    • A simple quantitative procedure using monolayer cultures for cytotoxicity assays (HTD/NR-90)
    • DOI 10.1007/BF01666038
    • E Borenfreund JA Puerner 1984 A simple quantitative procedure using monolayer culture for toxicity assays J Tissue Cult Methods 9 7 9 10.1007/BF01666038 (Pubitemid 15235618)
    • (1985) Journal of Tissue Culture Methods , vol.9 , Issue.1 , pp. 7-9
    • Borenfreund, E.1    Puerner, J.A.2
  • 8
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • 10.1016/0003-2697(76)90527-3
    • M Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 249 254 10.1016/0003-2697(76)90527-3
    • (1976) Anal Biochem , vol.72 , pp. 249-254
    • Bradford, M.1
  • 11
    • 0038744228 scopus 로고    scopus 로고
    • Molecular chains: Two new isomorphous coordination polymers of oxydiacetate
    • 10.1016/S1387-7003(03)00080-7
    • J Chao Z Xiang Y Zhao-Peng W Zhi-Yong 2003 Molecular chains: two new isomorphous coordination polymers of oxydiacetate Inorg Chem Commun 6 706 709 10.1016/S1387-7003(03)00080-7
    • (2003) Inorg Chem Commun , vol.6 , pp. 706-709
    • Chao, J.1    Xiang, Z.2    Zhao-Peng, Y.3    Zhi-Yong, W.4
  • 12
    • 0034622105 scopus 로고    scopus 로고
    • A possible role of oxidative stress in the vanadium-induced cytotoxicity in the MC3T3E1 osteoblast and UMR106 osteosarcoma cell lines
    • DOI 10.1016/S0300-483X(00)00181-5, PII S0300483X00001815
    • AM Cortizo L Bruzzone MS Molinuevo SB Etcheverry 2000 A possible role of oxidative stress in the vanadium-induced cytotoxicity in the MC3T3E1 osteoblast and UMR106 osteosarcoma cell lines Toxicology 147 89 99 10874156 10.1016/S0300-483X(00)00181-5 1:CAS:528:DC%2BD3cXktlKmtbs%3D (Pubitemid 30386909)
    • (2000) Toxicology , vol.147 , Issue.2 , pp. 89-99
    • Cortizo, A.M.1    Bruzzone, L.2    Molinuevo, S.3    Etcheverry, S.B.4
  • 13
    • 0035670563 scopus 로고    scopus 로고
    • A vanadium/aspirin complex controlled release using a poly(β-propiolactone) film. Effects on osteosarcoma cells
    • DOI 10.1163/156856201753252499
    • MS Cortizo JL Alessandrini SB Etcheverry AM Cortizo 2001 A vanadium/aspirin complex controlled release using a poly(beta-propiolactone) film: effects on osteosarcoma cells J Biomater Sci Polym 12 945 959 10.1163/156856201753252499 1:CAS:528:DC%2BD38XhvVCjsA%3D%3D (Pubitemid 34041514)
    • (2001) Journal of Biomaterials Science, Polymer Edition , vol.12 , Issue.9 , pp. 945-959
    • Cortizo, M.S.1    Alessandrini, J.L.2    Etcheverry, S.B.3    Cortizo, A.M.4
  • 14
    • 36749027238 scopus 로고    scopus 로고
    • Vanadium schiff base complexes: Chemistry, properties, and concerns about possible therapeutic applications
    • Kustin K, Costa Pessoa J, Crans DC (eds) ACS
    • Costa Pessoa J, Cavaco I, Correia I, Tomaz AI, Adão P, Vale I, Ribeiro V, Castro MM, Geraldes CC (2007) Vanadium schiff base complexes: chemistry, properties, and concerns about possible therapeutic applications. In: Kustin K, Costa Pessoa J, Crans DC (eds) Vanadium: the versatile metal. ACS symposium series, vol 974. ACS, pp 340-351
    • (2007) Vanadium: The Versatile Metal. ACS Symposium Series , vol.974 , pp. 340-351
    • Costa Pessoa J, C.1
  • 15
    • 1542378704 scopus 로고    scopus 로고
    • Dioxygen activation at mononuclear nonheme iron active sites: Enzymes, models, and intermediates
    • 14871146 10.1021/cr020628n 1:CAS:528:DC%2BD2cXnvFWjtg%3D%3D
    • M Costas MP Mehn L Jensen 2004 Dioxygen activation at mononuclear nonheme iron active sites: enzymes, models, and intermediates Chem Rev 104 939 986 14871146 10.1021/cr020628n 1:CAS:528:DC%2BD2cXnvFWjtg%3D%3D
    • (2004) Chem Rev , vol.104 , pp. 939-986
    • Costas, M.1    Mehn, M.P.2    Jensen, L.3
  • 16
    • 0034732827 scopus 로고    scopus 로고
    • Chemistry and insulin-like properties of vanadium(IV) and vanadium(V) compounds
    • DOI 10.1016/S0162-0134(00)00048-9, PII S0162013400000489
    • DC Crans 2000 Chemistry and insulin-like properties of vanadium(IV) and vanadium(V) compounds J Inorg Biochem 80 123 131 10885472 10.1016/S0162-0134(00) 00048-9 1:CAS:528:DC%2BD3cXkvVOrurg%3D (Pubitemid 30628773)
    • (2000) Journal of Inorganic Biochemistry , vol.80 , Issue.1-2 , pp. 123-131
    • Crans, D.C.1
  • 17
    • 19944390452 scopus 로고    scopus 로고
    • Synthesis, molecular structure and properties of oxo-vanadium(IV) complexes containing the oxydiacetate ligand
    • DOI 10.1039/b300914a
    • D Del Río A Galindo R Vicente C Mealli A Ienco D Masi 2003 Synthesis, molecular structure and properties of oxo vanadium(IV) complexes containing the oxydiacetate ligand Dalton Trans 9 1813 1820 10.1039/b300914a (Pubitemid 41282376)
    • (2003) Dalton Transactions , Issue.9 , pp. 1813-1820
    • Del Rio, D.1    Galindo, A.2    Vicente, R.3    Mealli, C.4    Ienco, A.5    Masi, D.6
  • 18
    • 0030832148 scopus 로고    scopus 로고
    • Induction of endothelial cell surface adhesion molecules by tumor necrosis factor is blocked by protein tyrosine phosphatase inhibitors: Role of the nuclear transcription factor NF-κB
    • DOI 10.1002/eji.1830270909
    • S Dharwan S Singh BB Aggarwal 1997 Induction of endothelial cell surface adhesion molecules by tumor necrosis factor is blocked by protein tyrosine phosphatase inhibitors: role of nuclear transcription factor NF-κB Eur Immunol 27 2172 2179 10.1002/eji.1830270909 (Pubitemid 27404297)
    • (1997) European Journal of Immunology , vol.27 , Issue.9 , pp. 2172-2179
    • Dhawan, S.1    Singh, S.2    Aggarwal, B.B.3
  • 19
    • 0029446465 scopus 로고
    • Antitumor activity of vanadium compounds
    • H. Sigel A. Sigel (eds). Marcel Dekker New York
    • Djordjevic C (1995) Antitumor activity of vanadium compounds. In: Sigel H, Sigel A (eds) Metal ions in biological systems, vol 31. Marcel Dekker, New York, pp 595-616
    • (1995) Metal Ions in Biological Systems 31 , pp. 595-616
    • Djordjevic, C.1
  • 20
    • 0032429015 scopus 로고    scopus 로고
    • Antitumor activities of vanadium(IV), manganese(IV), iron(III), cobalt(II) and copper(II) complexes of 2-methylaminopyridine
    • DOI 10.1016/S0304-3835(98)00213-4, PII S0304383598002134
    • MM El-Naggara AM El-Waseefa KM El-Halafawyb IH El-Sayed 1998 Antitumor activities of vanadium(IV), manganese(IV), iron(III), cobalt(II) and copper(II) complexes of 2-methylaminopyridine Cancer Lett 33 71 76 10.1016/S0304-3835(98) 00213-4 (Pubitemid 29069113)
    • (1998) Cancer Letters , vol.133 , Issue.1 , pp. 71-76
    • El-Naggar, M.M.1    El-Waseef, A.M.2    El-Halafawy, K.M.3    El-Sayed, I.H.4
  • 21
    • 0001219868 scopus 로고    scopus 로고
    • Bioactivity of Vanadium Compounds on Cells in Culture
    • Vanadium in the Environment. Part 1: Chemistry and Biochemistry
    • Etcheverry SB, Cortizo AM (1998) Bioactivity of vanadium compounds on cells in culture. In: Nriagu JO (ed) Vanadium in the environment. Advances in environmental science and technology; part A (chap 15). Wiley, New York, pp 359-394 (Pubitemid 128049976)
    • (1998) Advances in environmental science and technology -New York , vol.30 , pp. 359-394
    • Etcheverry, S.B.1    Cortizo, A.M.2
  • 23
    • 0036273321 scopus 로고    scopus 로고
    • Vanadium in cancer treatment
    • DOI 10.1016/S1040-8428(01)00221-9, PII S1040842801002219
    • AM Evangelou 2002 Vanadium in cancer treatment Crit Rev Oncol Hematol 42 249 265 12050018 10.1016/S1040-8428(01)00221-9 (Pubitemid 34615688)
    • (2002) Critical Reviews in Oncology/Hematology , vol.42 , Issue.3 , pp. 249-265
    • Evangelou, A.M.1
  • 24
    • 0030668588 scopus 로고    scopus 로고
    • Comparison of the therapeutic effects of two vanadium complexes administered at low doses on benzo[a]pyrene-induced malignant tumors in rats
    • DOI 10.1016/S0304-3835(97)00278-4, PII S0304383597002784
    • AM Evangelou S Karkabounas G Kalpouzos M Malamas R Liasko D Stefanou AT Vlahos TA Kabanos 1997 Comparison of the therapeutic effects of two vanadium complexes administered at low dose on benzo[a]pyrene-induced malignant tumors in rats Cancer Lett 119 221 225 9570375 10.1016/S0304-3835(97)00278-4 1:CAS:528:DyaK2sXms1elsL0%3D (Pubitemid 27478107)
    • (1997) Cancer Letters , vol.119 , Issue.2 , pp. 221-225
    • Evangelou, A.1    Karkabounas, S.2    Kalpouzos, G.3    Malamas, M.4    Liasko, R.5    Stefanou, D.6    Vlahos, A.T.7    Kabanos, T.A.8
  • 25
    • 84855331371 scopus 로고    scopus 로고
    • Chapter 1 "overview"
    • Farrell NP (ed) The Royal Society of Chemistry, Cambridge
    • Farrell NP (1999) Chapter 1 "Overview" In: Farrell NP (ed) Uses of inorganic chemistry in medicine. The Royal Society of Chemistry, Cambridge, p 16
    • (1999) Uses of Inorganic Chemistry in Medicine , pp. 16
    • Farrell, N.P.1
  • 26
    • 0032147090 scopus 로고    scopus 로고
    • 3-valproic acid generated by baculovirus-expressed CYP3A1
    • DOI 10.1006/abbi.1998.0742
    • MB Fisher SJ Thompson V Ribeiro MC Lechner A Rettie 1998 P450-catalyzed in-chain desaturation of valproic acid: isoform selectivity and mechanism of formation of Delta 3-valproic acid generated by baculovirus-expressed CYP3A1 Arch Biochem Biophys 356 63 70 9681992 10.1006/abbi.1998.0742 1:CAS:528:DyaK1cXltFyrsbs%3D (Pubitemid 28364355)
    • (1998) Archives of Biochemistry and Biophysics , vol.356 , Issue.1 , pp. 63-70
    • Fisher, M.B.1    Thompson, S.J.2    Ribeiro, V.3    Lechner, M.C.4    Rettie, A.E.5
  • 27
    • 48149086068 scopus 로고    scopus 로고
    • Vanadyl bisacetylacetonate induced G1/S cell cycle arrest via high-intensity ERK phosphorylation in HepG2 cells
    • 18483753 10.1007/s00775-008-0387-2 1:CAS:528:DC%2BD1cXovFOms7Y%3D
    • Y Fu Q Wang XG Yang XD Yang K Wang 2008 Vanadyl bisacetylacetonate induced G1/S cell cycle arrest via high-intensity ERK phosphorylation in HepG2 cells J Biol Inorg Chem 13 1001 1009 18483753 10.1007/s00775-008-0387-2 1:CAS:528:DC%2BD1cXovFOms7Y%3D
    • (2008) J Biol Inorg Chem , vol.13 , pp. 1001-1009
    • Fu, Y.1    Wang, Q.2    Yang, X.G.3    Yang, X.D.4    Wang, K.5
  • 28
    • 0034005632 scopus 로고    scopus 로고
    • Apoptosis-inducing vanadocene compounds against human testicular cancer
    • P Ghosh OJ D'Cruz RK Narla FM Uckun 2000 Apoptosis-inducing vanadocene compounds against human testicular cancer Clin Cancer Res 6 1536 1545 10778987 1:CAS:528:DC%2BD3cXjtVOqtbg%3D (Pubitemid 30226244)
    • (2000) Clinical Cancer Research , vol.6 , Issue.4 , pp. 1536-1545
    • Ghosh, P.1    D'Cruz, O.J.2    Narla, R.K.3    Uckun, F.M.4
  • 30
    • 0023094262 scopus 로고
    • Biphasic effect of vanadium salts on in vitro tumor colony growth
    • U Hanauske AR Hanauske MH Marshall VA Muggia DD Von Hoff 1987 Biphasic effect of vanadium salts on in vitro tumor colony growth Int J Cell Cloning 5 170 178 3106514 10.1002/stem.5530050209 1:CAS:528:DyaL2sXlsVKru7c%3D (Pubitemid 17045098)
    • (1987) International Journal of Cell Cloning , vol.5 , Issue.2 , pp. 170-178
    • Hanauske, U.1    Hanauske, A.-R.2    Marshall, M.H.3
  • 31
    • 0033761728 scopus 로고    scopus 로고
    • Antitumor metallocenes: Structure-activity studies and interactions with biomolecules
    • 11032972 1:CAS:528:DC%2BD3cXotFWrsr4%3D
    • MM Harding G Moksdi 2000 Antitumor metallocenes: structure-activity studies and interactions with biomolecules Curr Med Chem 7 1289 1293 11032972 1:CAS:528:DC%2BD3cXotFWrsr4%3D
    • (2000) Curr Med Chem , vol.7 , pp. 1289-1293
    • Harding, M.M.1    Moksdi, G.2
  • 32
    • 0027335670 scopus 로고
    • 2 with calf thymus DNA
    • DOI 10.1016/0014-5793(93)81588-Q
    • MM Harding GJ Harden LD Field 1993 A 31P NMR study of the interaction of the antitumor active metallocene Cp2MoCl2 with calf thymus DNA FEBS Lett 322 291 294 8486161 10.1016/0014-5793(93)81588-Q 1:CAS:528:DyaK3sXksVSnt7o%3D (Pubitemid 23144706)
    • (1993) FEBS Letters , vol.322 , Issue.3 , pp. 291-294
    • Harding, M.M.1    Harden, G.J.2    Field, L.D.3
  • 33
    • 0031973021 scopus 로고    scopus 로고
    • The ability of the Comet assay to discriminate between genotoxins and cytotoxins
    • DOI 10.1093/mutage/13.1.89
    • L Henderson A Wolfreys J Fedyk C Bourner S Windebank 1998 The ability of the Comet assay to discriminate between genotoxins and cytotoxins Mutagenesis 113 89 94 10.1093/mutage/13.1.89 (Pubitemid 28052511)
    • (1998) Mutagenesis , vol.13 , Issue.1 , pp. 89-94
    • Henderson, L.1    Wolfreys, A.2    Fedyk, J.3    Bourner, C.4    Windebank, S.5
  • 34
    • 0017064979 scopus 로고    scopus 로고
    • A fluorometric method for determination of oxidized and reduced glutathione in tissues
    • 10.1016/0003-2697(76)90326-2
    • PJ Hissin R Hilf 1996 A fluorometric method for determination of oxidized and reduced glutathione in tissues Anal Biochem 74 214 226 10.1016/0003- 2697(76)90326-2
    • (1996) Anal Biochem , vol.74 , pp. 214-226
    • Hissin, P.J.1    Hilf, R.2
  • 36
    • 48249146581 scopus 로고    scopus 로고
    • Sodium orthovanadate affects growth of some human epithelial cancer cells (A549, HTB44, DU145)
    • 10.3409/fb.56-3-4.115-121 1:CAS:528:DC%2BD1cXpvFGqu7Y%3D
    • A Klein P Holko J Ligeza AM Kordowiak 2008 Sodium orthovanadate affects growth of some human epithelial cancer cells (A549, HTB44, DU145) Folia Biol (Krakow) 56 115 121 10.3409/fb.56-3-4.115-121 1:CAS:528:DC%2BD1cXpvFGqu7Y%3D
    • (2008) Folia Biol (Krakow) , vol.56 , pp. 115-121
    • Klein, A.1    Holko, P.2    Ligeza, J.3    Kordowiak, A.M.4
  • 37
    • 0019519118 scopus 로고
    • In vitro cell growth inhibition by metallocene dichlorides
    • DOI 10.1007/BF00434391
    • P Kopf-Maier W Wagner H Kopf 1981 In vitro cell growth inhibition by metallocene dichlorides Cancer Chemother Pharmacol 5 237 241 7261252 10.1007/BF00434391 1:STN:280:DyaL3M3lvV2qsg%3D%3D (Pubitemid 11127417)
    • (1981) Cancer Chemotherapy and Pharmacology , vol.5 , Issue.4 , pp. 237-241
    • Koepf-Maier, P.1    Wagner, W.2    Koepf, H.3
  • 38
    • 73449111233 scopus 로고    scopus 로고
    • Titanium and vanadium complexes as anticancer agents
    • 19538167 1:CAS:528:DC%2BD1MXhtlShu73O
    • I Kostova 2009 Titanium and vanadium complexes as anticancer agents Anticancer Agents Med Chem 9 827 842 19538167 1:CAS:528:DC%2BD1MXhtlShu73O
    • (2009) Anticancer Agents Med Chem , vol.9 , pp. 827-842
    • Kostova, I.1
  • 39
    • 65649138401 scopus 로고    scopus 로고
    • The comet assay: A sensitive method for detecting DNA damage in individual cells
    • 19269328 10.1016/j.ymeth.2009.02.016 1:CAS:528:DC%2BD1MXmsVCltbk%3D
    • W Liao MA McNutt WG Zhu 2009 The comet assay: a sensitive method for detecting DNA damage in individual cells Methods 48 46 53 19269328 10.1016/j.ymeth.2009.02.016 1:CAS:528:DC%2BD1MXmsVCltbk%3D
    • (2009) Methods , vol.48 , pp. 46-53
    • Liao, W.1    McNutt, M.A.2    Zhu, W.G.3
  • 41
    • 0030898179 scopus 로고    scopus 로고
    • Generation of putative intrastrand cross-links and strand breaks in DNA by transition metal ion-mediated oxygen radical attack
    • DOI 10.1021/tx960158q
    • DR Lloyd DH Phillips PL Carmichael 1997 Generation of putative intrastrand cross-links and strand breaks in DNA by transition metal ion-mediated oxygen radical attack Chem Res Toxicol 10 393 400 9114975 10.1021/tx960158q 1:CAS:528:DyaK2sXisF2ntbk%3D (Pubitemid 27176300)
    • (1997) Chemical Research in Toxicology , vol.10 , Issue.4 , pp. 393-400
    • Lloyd, D.R.1    Phillips, D.H.2    Carmichael, P.L.3
  • 42
    • 0034102255 scopus 로고    scopus 로고
    • Tumor-derived mutated E-cadherin influences β-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate
    • B Luber S Candidus G Handsbusch E Mentele P Hutzler S Feller J Voss H Höfler KF Becker 2000 Tumor derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate Cell Adhes Commun 7 391 408 10830618 10.3109/15419060009109021 1:CAS:528:DC%2BD3cXktVKmtLc%3D (Pubitemid 30265256)
    • (2000) Cell Adhesion and Communication , vol.7 , Issue.5 , pp. 391-408
    • Luber, B.1    Candidus, S.2    Handschuh, G.3    Mentele, E.4    Hutzler, P.5    Feller, S.6    Voss, J.7    Hofler, H.8    Becker, K.-F.9
  • 43
    • 29944442370 scopus 로고    scopus 로고
    • The role of a novel copper complex in overcoming doxorubicin resistance in Ehrlich ascites carcinoma cells in vivo
    • DOI 10.1016/j.cbi.2005.10.044, PII S0009279705002851
    • S Majumder P Dutta A Mookerjee SK Choudhuri 2006 The role of a novel copper complex in overcoming doxorubicin resistance in Ehrlich ascites carcinoma cells in vivo Chem Biol Interact 159 90 103 16289015 10.1016/j.cbi.2005.10.044 1:CAS:528:DC%2BD28XhsFemtQ%3D%3D (Pubitemid 43042617)
    • (2006) Chemico-Biological Interactions , vol.159 , Issue.2 , pp. 90-103
    • Majumder, S.1    Dutta, P.2    Mookerjee, A.3    Choudhuri, S.K.4
  • 44
    • 39749182763 scopus 로고    scopus 로고
    • Vanadium(IV) complexes inhibit adhesion, migration and colony formation of UMR106 osteosarcoma cells
    • DOI 10.1007/s00280-007-0532-6
    • MS Molinuelo AM Cortizo SB Etcheverry 2008 Vanadium(IV) complexes inhibit adhesion, migration and colony formation of UMR106 osteosarcoma cells Cancer Chemother Pharmacol 61 767 773 10.1007/s00280-007-0532-6 (Pubitemid 351302032)
    • (2008) Cancer Chemotherapy and Pharmacology , vol.61 , Issue.5 , pp. 767-773
    • Molinuevo, M.S.1    Cortizo, A.M.2    Etcheverry, S.B.3
  • 45
    • 0442282174 scopus 로고    scopus 로고
    • Antitumoral properties of two new vanadyl(IV) complexes in osteoblasts in culture: Role of apoptosis and oxidative stress
    • DOI 10.1007/s00280-003-0708-7
    • MS Molinuevo DA Barrio AM Cortizo SB Etcheverry 2004 Antitumoral properties of two new vanadyl(IV) complexes in osteoblasts in culture: role of apoptosis and oxidative stress Cancer Chemother Pharmacol 53 163 172 14551736 10.1007/s00280-003-0708-7 1:CAS:528:DC%2BD3sXhtVSjsLfN (Pubitemid 38186996)
    • (2004) Cancer Chemotherapy and Pharmacology , vol.53 , Issue.2 , pp. 163-172
    • Molinuevo, M.S.1    Barrio, D.A.2    Cortizo, A.M.3    Etcheverry, S.B.4
  • 46
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • T Mosmann 1983 Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Methods 65 55 63 6606682 10.1016/0022-1759(83)90303-4 1:STN:280:DyaL2c%2FovFSmtw%3D%3D (Pubitemid 14203433)
    • (1983) Journal of Immunological Methods , vol.65 , Issue.1-2 , pp. 55-63
    • Mosmann, T.1
  • 47
    • 0031081210 scopus 로고    scopus 로고
    • Determination of catalase activity at physiological hydrogen peroxide concentrations
    • DOI 10.1006/abio.1996.9939
    • S Mueller HD Riedel W Stremmel 1997 Determination of catalase activity at physiological hydrogen peroxide concentrations Anal Biochem 245 55 60 9025968 10.1006/abio.1996.9939 1:CAS:528:DyaK2sXpsFWnsQ%3D%3D (Pubitemid 27053418)
    • (1997) Analytical Biochemistry , vol.245 , Issue.1 , pp. 55-60
    • Mueller, S.1    Riedel, H.-D.2    Stremmel, W.3
  • 48
    • 0028064949 scopus 로고
    • 2 with nucleic acid constituents
    • DOI 10.1021/jm00039a005
    • JH Murray MM Harding 1994 Organometallic anticancer agents: the effects of central metal and halide ligands on the interaction of metallocene dihalides Cp2MX2 with nucleic acid constituents J Med Chem 37 1936 1941 8027975 10.1021/jm00039a005 1:CAS:528:DyaK2cXktlKisrs%3D (Pubitemid 24233605)
    • (1994) Journal of Medicinal Chemistry , vol.37 , Issue.13 , pp. 1936-1941
    • Murray, J.H.1    Harding, M.M.2
  • 49
    • 0034902239 scopus 로고    scopus 로고
    • Bis(4,7-dimethyl-1,10-phenanthroline) sulfatooxovanadium(IV) as a novel antileukemic agent with matrix metalloproteinase inhibitory activity
    • RK Narla Y Dong D Klis FM Uckun 2001 Bis(4,7-dimethyl-1,10- phenanthroline) sulfatooxovanadium(IV) as a novel antileukemic agent with matrix metalloproteinase inhibitory activity Clin Cancer Res 7 1094 1101 11309362 1:CAS:528:DC%2BD3MXjs1eltb8%3D (Pubitemid 32708750)
    • (2001) Clinical Cancer Research , vol.7 , Issue.4 , pp. 1094-1101
    • Narla, R.K.1    Dong, Y.2    Klis, D.3    Uckun, F.M.4
  • 50
    • 0035020025 scopus 로고    scopus 로고
    • Vanadocenes as potent anti-proliferative agents disrupting mitotic spindle formation in cancer cells
    • DOI 10.1097/00001813-200104000-00010
    • CS Navara A Benyumov A Vassilev RK Narla P Ghosh FM Uckun 2001 Vanadocenes as potent anti-proliferative agents disrupting mitotic spindle formation in cancer cells Anticancer Drugs 12 369 376 11335794 10.1097/00001813-200104000-00010 1:CAS:528:DC%2BD3MXktVSks7o%3D (Pubitemid 32453443)
    • (2001) Anti-Cancer Drugs , vol.12 , Issue.4 , pp. 369-376
    • Navara, C.S.1    Benyumov, A.2    Vassilev, A.3    Narla, R.K.4    Ghosh, P.5    Uckun, F.M.6
  • 51
    • 0026503304 scopus 로고
    • Sensitive colorimetric bioassays for insulin-like growth factor (IGF) stimulation of cell proliferation and glucose consumption: Use in studies of IGF analogs
    • 1372238 10.1210/en.130.4.2201 1:CAS:528:DyaK38Xit1ygt7k%3D
    • T Okajima K Nakamura H Zhang N Ling T Tanabe T Yasuda RG Rosenfeld 1992 Sensitive colorimetric bioassays for insulin-like growth factor (IGF) stimulation of cell proliferation and glucose consumption: use in studies of IGF analogs Endocrinology 130 2201 2212 1372238 10.1210/en.130.4.2201 1:CAS:528:DyaK38Xit1ygt7k%3D
    • (1992) Endocrinology , vol.130 , pp. 2201-2212
    • Okajima, T.1    Nakamura, K.2    Zhang, H.3    Ling, N.4    Tanabe, T.5    Yasuda, T.6    Rosenfeld, R.G.7
  • 52
    • 34948907293 scopus 로고    scopus 로고
    • Spectroscopic characterization of a VO2+ complex of oxodiacetic acid and its bioactivity on osteoblast-like cells in culture
    • DOI 10.1007/s12011-007-0025-9
    • 2+ complex of oxodiacetic acid and its bioactivity on osteoblast-like cells in culture Biol Trace Elem Res 118 159 166 17873358 10.1007/s12011-007-0025-9 1:CAS:528:DC%2BD2sXhtVelsb%2FM (Pubitemid 47530810)
    • (2007) Biological Trace Element Research , vol.118 , Issue.2 , pp. 159-166
    • Rivadeneira, J.1    Barrio, D.A.2    Etcheverry, S.B.3    Baran, E.J.4
  • 53
    • 77950896402 scopus 로고    scopus 로고
    • Cytotoxicity of a vanadyl(IV) complex with a multidentate oxygen donor in osteoblast cell lines in culture
    • 20402656 10.2174/157340610791208754 1:CAS:528:DC%2BC3cXmtFehtbs%3D
    • J Rivadeneira AL Di Virgilio DA Barrio CI Muglia L Bruzzone SB Etcheverry 2010 Cytotoxicity of a vanadyl(IV) complex with a multidentate oxygen donor in osteoblast cell lines in culture Med Chem 6 9 23 20402656 10.2174/ 157340610791208754 1:CAS:528:DC%2BC3cXmtFehtbs%3D
    • (2010) Med Chem , vol.6 , pp. 9-23
    • Rivadeneira, J.1    Di Virgilio, A.L.2    Barrio, D.A.3    Muglia, C.I.4    Bruzzone, L.5    Etcheverry, S.B.6
  • 54
    • 0042133120 scopus 로고    scopus 로고
    • Genotoxic effects of vanadium(IV) in human peripheral blood cells
    • DOI 10.1016/S0378-4274(03)00255-8
    • JJ Rodríguez-Mercado E Roldán-Reyes M Altamirano-Lozano 2003 Genotoxic effects of vanadium(IV) in human peripheral blood cells Toxicol Lett 144 359 369 12927353 10.1016/S0378-4274(03)00255-8 (Pubitemid 36966719)
    • (2003) Toxicology Letters , vol.144 , Issue.3 , pp. 359-369
    • Rodriguez-Mercado, J.J.1    Roldan-Reyes, E.2    Altamirano-Lozano, M.3
  • 56
    • 0028113394 scopus 로고
    • Vanadium distribution in rats and DNA cleavage by vanadyl complex: Implication for vanadium toxicity and biological effects
    • H Sakurai 1994 Vanadium distribution in rats and DNA cleavage by vanadyl complex: implication for vanadium toxicity and biological effects Environ Health Perspect 3 35 36 (Pubitemid 24316355)
    • (1994) Environmental Health Perspectives , vol.102 , Issue.SUPPL. 3 , pp. 35-36
    • Sakurai, H.1
  • 57
    • 0028796632 scopus 로고
    • Mechanism for a new vanadium complex: Hydroxyl radical-dependent DNA cleavage by 1,10-phenanthroline-vanadyl complex in the presence of hydrogen peroxide
    • 7818512 10.1006/bbrc.1995.1019 1:CAS:528:DyaK2MXjtVWmurg%3D
    • H Sakurai H Tamura K Okatani 1995 Mechanism for a new vanadium complex: hydroxyl radical-dependent DNA cleavage by 1,10-phenanthroline-vanadyl complex in the presence of hydrogen peroxide Biochem Biophys Res Commun 206 133 137 7818512 10.1006/bbrc.1995.1019 1:CAS:528:DyaK2MXjtVWmurg%3D
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 133-137
    • Sakurai, H.1    Tamura, H.2    Okatani, K.3
  • 58
    • 48949090763 scopus 로고    scopus 로고
    • 2 vitamin D3 combination in inhibitions of 1,2-dimethylhydrazine-induced rat colon carcinogenesis
    • 18539154 10.1016/j.bbagen.2008.05.003 1:CAS:528:DC%2BD1cXhtVShsrbN
    • 2 vitamin D3 combination in inhibitions of 1,2-dimethylhydrazine-induced rat colon carcinogenesis Biochim Biophys Acta 1780 1106 1114 18539154 10.1016/j.bbagen.2008.05.003 1:CAS:528:DC%2BD1cXhtVShsrbN
    • (2008) Biochim Biophys Acta , vol.1780 , pp. 1106-1114
    • Samanta, S.1    Chatterjee, M.2    Ghosh, B.3    Rajkumar, M.4    Rana, A.5    Chatterjee, M.6
  • 59
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • 3345800 10.1016/0014-4827(88)90265-0 1:CAS:528:DyaL1cXhvVWmtbc%3D
    • NP Singh MT McCoy RR Tice EL Schneider 1988 A simple technique for quantitation of low levels of DNA damage in individual cells Exp Cell Res 175 184 191 3345800 10.1016/0014-4827(88)90265-0 1:CAS:528:DyaL1cXhvVWmtbc%3D
    • (1988) Exp Cell Res , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 60
    • 0029939911 scopus 로고    scopus 로고
    • Sequestration of mitotic (M-phase) chromosomes in autophagosomes: Mitotic programmed cell death in human Chang liver cells induced by an OH*burst from vanadyl(4)
    • DOI 10.1002/(SICI)1097-0185(199605)245:1<1::AID-AR1>3.0.CO;2-2
    • KH Sit R Paramananthan B Bay KP Wong HL Chan P Thong E Watt 1996 Sequestration of mitotic (M-phase) chromosomes in autophagosomes: mitotic programmed cell death in human Chang liver cells induced by an OH burst from vanadyl(IV) Anat Rec 245 1 8 8731032 10.1002/(SICI)1097-0185(199605)245:1<1:: AID-AR1>3.0.CO;2-2 1:CAS:528:DyaK28XjtVWrsrY%3D (Pubitemid 26121558)
    • (1996) Anatomical Record , vol.245 , Issue.1 , pp. 1-8
    • Sit, K.H.1    Paramanantham, R.2    Bay, B.H.3    Chan, H.L.4    Wong, K.P.5    Thong, P.6    Watt, F.7
  • 61
    • 41849134685 scopus 로고    scopus 로고
    • Vanadate induces necrotic death in neonatal rat cardiomyocytes through mitochondrial membrane depolarization
    • DOI 10.1021/tx700204r
    • SS Soares F Henao M Aureliano C Gutiérrez-Merino 2008 Vanadote induces necrotic death in neonatal rat cardiomyocytes through mitochondrial membrane depolarization Chem Res Toxicol 21 607 618 18251508 10.1021/tx700204r 1:CAS:528:DC%2BD1cXhsFGkt7g%3D (Pubitemid 351498037)
    • (2008) Chemical Research in Toxicology , vol.21 , Issue.3 , pp. 607-618
    • Soares, S.S.1    Henao, F.2    Aureliano, M.3    Gutierrez-Merino, C.4
  • 62
    • 0023010941 scopus 로고
    • 2, with nucleotides and phosphoesters. Mechanistic implications for a new class of antitumor agents
    • DOI 10.1021/ja00283a022
    • JH Toney CP Brock TJ Marks 1986 Aqueous coordination chemistry of vanadocene dichloride, with nucleotides and phosphoesters. Mechanistic implication for a new class of antitumor agents J Am Chem Soc 108 7263 7274 10.1021/ja00283a022 1:CAS:528:DyaL28XmtV2gs7k%3D (Pubitemid 17188955)
    • (1986) Journal of the American Chemical Society , vol.108 , Issue.23 , pp. 7263-7274
    • Toney, J.H.1    Brock, C.P.2    Marks, T.J.3
  • 63
    • 1442327683 scopus 로고    scopus 로고
    • Vanadyl sulfate can differentially damage DNA in human lymphocytes and HeLa cells
    • DOI 10.1007/s00204-003-0506-3
    • K Wozniak J Blasiak 2004 Vanadyl sulfate can differentially damage DNA in human lymphocytes and HeLa cells Arch Toxicol 78 7 15 13680095 10.1007/s00204-003-0506-3 1:CAS:528:DC%2BD2cXmtlGjtg%3D%3D (Pubitemid 38269934)
    • (2004) Archives of Toxicology , vol.78 , Issue.1 , pp. 7-15
    • Wozniak, K.1    Blasiak, J.2
  • 64
    • 3042803540 scopus 로고    scopus 로고
    • The permeability and cytotoxicity of insulin-mimetic vanadium compounds
    • DOI 10.1023/B:PHAM.0000029293.89113.d5
    • XG Yang XD Yang L Yuan K Wang DC Crans 2004 The permeability and cytotoxicity of insulin-mimetic vanadium compounds Pharm Res 21 1026 1033 15212169 10.1023/B:PHAM.0000029293.89113.d5 1:CAS:528:DC%2BD2cXktlyktLc%3D (Pubitemid 38870154)
    • (2004) Pharmaceutical Research , vol.21 , Issue.6 , pp. 1026-1033
    • Yang, X.-G.1    Yang, X.-D.2    Yuan, L.3    Wang, K.4    Crans, D.C.5
  • 65
    • 0025719327 scopus 로고
    • Effect of antioxidants on vanadate-induced toxicity towards isolated perfused rat livers
    • 1763411 10.1016/0300-483X(91)90041-X 1:CAS:528:DyaK38XnvVSlug%3D%3D
    • M Younes E Kayserb O Strubelt 1991 Effect of antioxidants on vanadate-induced toxicity towards isolated perfused rat livers Toxicology 70 141 149 1763411 10.1016/0300-483X(91)90041-X 1:CAS:528:DyaK38XnvVSlug%3D%3D
    • (1991) Toxicology , vol.70 , pp. 141-149
    • Younes, M.1    Kayserb, E.2    Strubelt, O.3


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