The conditioned medium from a stable human GDF3-expressing CHO cell line, induces the differentiation of PC12 cells

Molecular and Cellular Biochemistry

Volumn 359, Issue 1-2, 2012, Pages 115-123

  Li, Qiang ^a   Liu, Xianghua ^a   Wu, Yanhua ^a   An, Jian ^a   Hexige, Saiyin ^a   Ling, Yichen ^a   Zhang, Mingjun ^a   Yang, Xianmei ^a   Yu, Long ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

ALK7; Differentiation; GDF3; PC12; Proliferation; TGF superfamily

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE 7; GROWTH DIFFERENTIATION FACTOR 1; GROWTH DIFFERENTIATION FACTOR 3; PROTEIN SERINE THREONINE KINASE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN TISSUE; CELL DIFFERENTIATION; CELL GROWTH; CELL STRAIN; CHO CELL; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPLASM; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENETIC TREE; PROTEIN EXPRESSION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; BRAIN; BRAIN CHEMISTRY; CELL DIFFERENTIATION; CHO CELLS; CRICETINAE; CULTURE MEDIA, CONDITIONED; GROWTH DIFFERENTIATION FACTOR 1; GROWTH DIFFERENTIATION FACTOR 3; HUMANS; PC12 CELLS; RATS; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION;

EID: 83555173363     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-1005-0     Document Type: Article

References (26)

1. JM Yingling KL Blanchard JS Sawyer 2004 Development of TGF-beta signalling inhibitors for cancer therapy Nat Rev Drug Discov 3 1011 1022 15573100 10.1038/nrd1580 1:CAS:528:DC%2BD2cXhtVarsL3L (Pubitemid 39642364)
2. M de Caestecker 2004 The transforming growth factor-beta superfamily of receptors Cytokine Growth Factor Rev 15 1 11 14746809 10.1016/j.cytogfr.2003.10. 004 (Pubitemid 38121286)
3. DB Constam EJ Robertson 1999 Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases J Cell Biol 144 139 149 9885250 10.1083/jcb.144.1.139 1:CAS:528:DyaK1MXjs1yhtQ%3D%3D (Pubitemid 29047017)
4. SS Molloy PA Bresnahan SH Leppla KR Klimpel G Thomas 1992 Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen J Biol Chem 267 16396 16402 1644824 1:CAS:528:DyaK38XlsVKjtrk%3D
5. JW Creemers PJ Groot Kormelink AJ Roebroek K Nakayama WJ Van de Ven 1993 Proprotein processing activity and cleavage site selectivity of the Kex2-like endoprotease PACE4 FEBS Lett 336 65 69 8262218 10.1016/0014-5793(93)81610-C 1:CAS:528:DyaK2cXhvVGru7g%3D (Pubitemid 23362004)
6. M Hosaka K Murakami K Nakayama 1994 PACE4 is a ubiquitous endoprotease that has similar but not identical substrate specificity to other KEX2-like processing endoproteases Biomed Res 16 383 390
7. A Herpin C Lelong P Favrel 2004 Transforming growth factor-beta-related proteins: an ancestral and widespread superfamily of cytokines in metazoans Dev Comp Immunol 28 461 485 15062644 10.1016/j.dci.2003.09.007 1:CAS:528: DC%2BD2cXhtFCjtLo%3D (Pubitemid 38177448)
8. S Daopin KA Piez Y Ogawa DR Davies 1992 Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily Science 257 369 373 1631557 10.1126/science.1631557 1:STN:280:DyaK38zjsFyrsw%3D%3D
9. MP Schlunegger MG Grutter 1992 An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2 Nature 358 430 434 1641027 10.1038/358430a0 1:CAS:528:DyaK38XltVCntr4%3D
10. K Miyazawa M Shinozaki T Hara T Furuya K Miyazono 2002 Two major Smad pathways in TGF-beta superfamily signalling Genes Cells 7 1191 1204 12485160 10.1046/j.1365-2443.2002.00599.x 1:CAS:528:DC%2BD3sXhtV2htg%3D%3D (Pubitemid 36024597)
11. AC McPherron SJ Lee 1993 GDF-3 and GDF-9: two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines J Biol Chem 268 3444 3449 8429021 1:CAS:528:DyaK3sXisVOrtrw%3D (Pubitemid 23070981)
12. W Wang Y Yang Y Meng Y Shi 2004 GDF-3 is an adipogenic cytokine under high fat dietary condition Biochem Biophys Res Commun 321 1024 1031 15358131 10.1016/j.bbrc.2004.07.058 1:CAS:528:DC%2BD2cXmt1Ogtbg%3D (Pubitemid 39044412)
13. O Andersson M Korach-Andre E Reissmann CF Ibáñez P Bertolino 2008 Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity Proc Natl Acad Sci 105 7252 7256 18480259 10.1073/pnas.0800272105 1:CAS:528:DC%2BD1cXmsFCqs74%3D (Pubitemid 351754464)
14. JJ Shen L Huang L Li C Jorgez MM Matzuk CW Brown 2009 Deficiency of growth differentiation factor 3 protects against diet-induced obesity by selectively acting on white adipose Mol Endocrinol 23 113 123 19008465 10.1210/me.2007-0322 1:CAS:528:DC%2BD1MXnsFOitQ%3D%3D
15. AT Clark RT Rodriguez MS Bodnar MJ Abeyta MI Cedars PJ Turek MT Firpo RA Reijo Pera 2004 Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma Stem Cells 22 169 179 14990856 10.1634/stemcells.22-2-169 1:CAS:528: DC%2BD2cXis1Sgsbk%3D (Pubitemid 38282632)
16. UI Ezeh PJ Turek RA Reijo AT Clark 2005 Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma Cancer 104 2255 2265 16228988 10.1002/cncr.21432 1:CAS:528: DC%2BD2MXht1Cksr7M (Pubitemid 41579973)
17. O Andersson P Bertolino CF Ibáñez 2007 Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development Dev Biol 11 500 511 10.1016/j.ydbio.2007.08.060 (Pubitemid 350046540)
18. C Chen SM Ware A Sato DE Houston-Hawkins R Habas MM Matzuk MM Shen CW Brown 2006 The Vg1-related protein Gdf3 acts in a nodal signaling pathway in the pre-gastrulation mouse embryo Development 133 319 329 16368929 10.1242/dev.02210 1:CAS:528:DC%2BD28XhsFamsr0%3D (Pubitemid 43210720)
19. AJ Levine AH Brivanlou 2006 GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos Development 133 209 216 16339188 10.1242/dev.02192 1:CAS:528:DC%2BD28XhsFanu70%3D (Pubitemid 43210710)
20. N Saitou M Nei 1987 The neighbor-joining method: a new method for reconstructing phylogenetic trees Mol Biol Evol 4 406 425 3447015 1:STN:280:DyaL1c7ovFSjsA%3D%3D
21. Y Wu J Zuo G Ji H Saiyin X Liu F Yin N Cao Y Wen JJ Li L Yu 2009 Proapoptotic function of integrin beta(3) in human hepatocellular carcinoma cells Clin Cancer Res 15 60 69 19118033 10.1158/1078-0432.CCR-08-1028 1:CAS:528:DC%2BD1MXhs1Cjtw%3D%3D
22. S Hexige J Guo L Ma Y Sun X Liu L Ma X Yan Z Li L Yu 2005 Expression pattern of growth/differentiation factor 3 in human and murine cerebral cortex, hippocampus as well as cerebellum Neurosci Lett 389 83 87 16126341 10.1016/j.neulet.2005.06.071 1:CAS:528:DC%2BD2MXpvFelt7w%3D (Pubitemid 41242890)
23. H Jörnvall A Blokzijl P ten Dijke CF Ibáñez 2001 The orphan receptor serine/threonine kinase ALK7 signals arrest of proliferation and morphological differentiation in a neuronal cell line J Biol Chem 276 5140 5146 11084022 10.1074/jbc.M005200200
24. AJ Levine ZJ Levine AH Brivanlou 2009 GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses Dev Biol 325 43 48 18823971 10.1016/j.ydbio.2008.09.006 1:CAS:528:DC%2BD1cXhsFCls7bI
25. G Ge DR Hopkins WB Ho DS Greenspan 2005 GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells Mol Cell Biol 25 5846 5858 15988002 10.1128/MCB.25.14.5846-5858.2005 1:CAS:528:DC%2BD2MXmvVeit7o%3D (Pubitemid 40946542)
26. YJ Yang HJ Lee DH Choi HS Huang SC Lim MK Lee 2008 Effect of scoparone on neurite outgrowth in PC12 cells Neurosci Lett 440 14 18 18547723 10.1016/j.neulet.2008.05.051 1:CAS:528:DC%2BD1cXnt1Slu7s%3D