Analgesic and anti-inflammatory activity and pharmacokinetics of alkaloids from seeds of Strychnos nux-vomica after transdermal administration: Effect of changes in alkaloid composition

Journal of Ethnopharmacology

Volumn 139, Issue 1, 2012, Pages 181-188

  Chen, Jun ^a,b   Wang, Xuan ^a,b   Qu, Yan Ge ^a,b   Chen, Zhi Peng ^a,b   Cai, Hao ^a,b   Liu, Xiao ^a,b   Xu, Fei ^a   Lu, Tu Lin ^a,b   Cai, Bao Chang ^a,b  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Analgesic; Anti inflammatory; Brucine; Strychnine; Strychnos nux vomica L.; Transdermal

Indexed keywords

ALKALOID; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; BRUCINE; DICLOFENAC DIETHYLAMINE; STRYCHNINE; STRYCHNOS NUX VOMICA MODIFIED TOTAL ALKALOID FRACTION; STRYCHNOS NUX VOMICA TOTAL ALKALOID FRACTION; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; DRUG PENETRATION; DRUG SCREENING; DRUG SYNTHESIS; EDEMA; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PAIN; PLANT SEED; SKIN PENETRATION; STRYCHNOS NUX VOMICA; WRITHING TEST;

ACETIC ACID; ADMINISTRATION, CUTANEOUS; ALKALOIDS; ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; EDEMA; HOT TEMPERATURE; INFLAMMATION; MALE; MICE; MICE, INBRED ICR; PAIN; PHYTOTHERAPY; PLANT EXTRACTS; SEEDS; SKIN ABSORPTION; STRYCHNOS NUX-VOMICA; XYLENES;

LOGANIACEAE; STRYCHNOS NUX-VOMICA; STRYCHNOS TOXIFERA;

EID: 83555161507     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.10.038     Document Type: Article

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