A cannabinoid ligand, anandamide, exacerbates endotoxin-induced uveitis in rabbits

Journal of Ocular Pharmacology and Therapeutics

Volumn 27, Issue 6, 2011, Pages 545-552

  Altinsoy, Ali ^a   Dileköz, Ergin ^a   Kul, Oguz ^b   Ilhan, Sevil Ö ^a   Tunccan, Özlem G ^a   Seven, Ilgim ^a   Bagriacik, Emin Umit ^a   Sarioglu, Yusuf ^a   Or, Meral ^a   Ercan, Zeynep Sevim ^a  

^a GAZI UNIVERSITY FACULTY OF MEDICINE   (Turkey)

^b KIRIKKALE UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; ANANDAMIDE; ENDOTOXIN; LIPOPOLYSACCHARIDE; PENTOBARBITAL;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR EYE CHAMBER; AQUEOUS HUMOR; ARTICLE; CELL COUNT; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG EFFECT; ENUCLEATION; LEUKOCYTE; MALE; MICROBIAL CONTAMINATION; NONHUMAN; RABBIT; UVEITIS; VITREOUS BODY;

ANIMALS; ARACHIDONIC ACIDS; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; INTRAVITREAL INJECTIONS; LEUKOCYTE COUNT; LIPOPOLYSACCHARIDES; MALE; NEUTROPHIL INFILTRATION; PIPERIDINES; POLYUNSATURATED ALKAMIDES; PYRAZOLES; RABBITS; RECEPTOR, CANNABINOID, CB1; RECEPTORS, CANNABINOID; SEVERITY OF ILLNESS INDEX; UVEITIS;

EID: 83455255180     PISSN: 10807683     EISSN: 15577732     Source Type: Journal    
DOI: 10.1089/jop.2011.0049     Document Type: Article

References (41)

1. Rao, N.A., Forster, D.J., and Augsburger, J.J. The Uvea:Uveitis and Intraocular Neoplasms. New York: Gower; 1992; pp. 1-18.
2. Nussenblatt, R.B., Withcup, S.M., and Paletsine, A.G. Fundamentals and Clinical Practice. 2nd ed. St Louis: Mosby; 1996.
3. Caspi, R., Roberge, F., Chan, C.C., and Wiggert, B. A new model of autoimmune disease experimental autoimmune uveoretinitis induved in mice with two different retinal antigens. J. Immunol. 140:1490-1495, 1988.
4. Rosenbaum, J.T., McDevitt, H.O., Guss, R.B., and Egberg, P.R. Endotoxin-induced uveitis in rats as a model for human disease. Nature 286:611-613, 1980. (Pubitemid 10015368)
5. Cousins, S.W., Guss, R.B., Howes, E.L.J., and Rosenbaum, J.T. Endotoxin induced uveitis in the rat: observations on altered vascular permeability, clinical findings and histology. Exp. Eye Res. 39:665-676, 1984. (Pubitemid 15177186)
6. Hoekzema, R., Murray, P.I., Van Harren, M.A.C., Helle, M., and Kijlstra, A. Analysis of interleukin-6 in endotoxin induced uveitis. Invest. Ophthalmol. Vis. Sci. 32:88-95, 1991.
7. Streilein, J.W. (ed). Immune Response and the Eye (Chemical Immunology, vol 73). Basel: Karger; 1999; pp 11-38.
8. Dewey, W.L. Cannabinoid pharmacology. Pharmacol. Rev. 38:151-178, 1986. (Pubitemid 16001329)
9. Agurell, S., Halldin, M., and Lindgren, J.E. Pharmacokinetics and metabolism of delta-1-tetrahydrocannabinol and other cannabinoids with emphasis on man. Pharmacol. Rev. 38:21-43, 1986. (Pubitemid 16077324)
10. Hollister, L.E. Health aspects of cannabis. Phramacol. Rev. 38:1-20, 1986. (Pubitemid 16077323)
11. Pate, D. Glaucoma and cannabinoids. In: Grotenhermen, F., Russo, E. eds. Cannabis and Cannabinoids: Pharmacology, Toxicology and Therapeutic Potential. Binghamton, NY: Haworth Press; 2002; pp. 215-224.
12. Grotenhermen, F. Pharmacokinetics and pharmacodynamics of cannabinoids. Clin. Pharmacokinet. Rev. 42:327-360, 2003. (Pubitemid 36433875)
13. Di Marzo, V., Fontana, A., Cadas, H., Schinelli, S., Cimino, G., Schwartz, J.C., and Piomelli, D. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature 372:686-691, 1994.
14. Devane, W.A., Hanus, L., and Breuer, A. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258:1946-1949, 1992. (Pubitemid 23026736)
15. Devane, W.A., and Breuer, A. A novel probe fort he cannabinoid receptor. J. Med. Chem. 35:2065-2069, 1992.
16. Devane, W.A., Dysarz, III, F.A., and Johnson, M.R. Determination and characterization of a cannabinoid receptor in rat brain. Mol. Pharmacol. 34:605-613, 1998.
17. 2 receptor-mediated actions of anandamide in Mouse brain. J. Neurochem. 75:2434-2444, 2000.
18. Matsuda, S., and Kanemitsu, N. Metabolism of anandamide, an endogenous ligand in porcine ocular tissues. Exp. Eye Res. 64:707-711, 1997. (Pubitemid 27278298)
19. De Petrocellis, L., Melck, D., and Bisogno, T. Endocannabinoids and fatty acid amides in cancer, inflammation and related disorders. Chem. Phys. Lipids 108:191-209, 2000.
20. Di Marzo, V. Endocannabinoids and othe fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance. Biochim. Biophys. Acta 1392:153-175, 1998. (Pubitemid 28287321)
21. Mikawa, Y., Matsuda, S., Kanagawa, T., TajikaiT., Ueda, N., and Mimura, Y. Ocular activity of topically adminidtered anandamide in rabbit. Jpn. J. Opthalmol. 41:217-220, 1997. (Pubitemid 27455311)
22. Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J. Protein measurment with the Folin phenol reagent. J. Biol. Chem. 193:265-275, 1951.
23. Tilton, R.G., Chang, K., Corbett, J.A., Misko, T.P., Currie, M.G., Bora, N.S., Kaplan, H.J., and Williamson, J.R. Endotoxin-induced uveitis in the rat is attenuated by inhibition of nitric oxide production. Invest. Ophthalmol. Vis. Sci. 35: 3278-3288, 1994. (Pubitemid 24241366)
24. Chiang, C.W., Barnett, G., and Brine, D. Systemic absorption of 9-tetra-hydrocannabinol after ophthalmic administration to the rabbit. J. Pharm. Sci. 72:136-138, 1983. (Pubitemid 13139940)
25. Colasanti, B.K. A comparison of the ocular and central effects of delta-9-tetrahydrocannabinol and cannabigerol. J. Ocul. Pharmacol. 6:259-269, 1990.
26. 1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br. J. Pharmacol. 134:845-852, 2001. (Pubitemid 33016156)
27. Straiker, A.J., Maguire, G., Mackie, K., and Lindsey, J. Localization of cannabinoid CB1 receptors in human anterior eye and retina. Invest. Ophthalmol. Vis. Sci. 40:2442-2448, 1999. (Pubitemid 29418406)
28. 1 receptors and ligands in vertebrate retina: localization and function of an endogenous signaling system. Proc. Natl. Acad. Sci. 96:14565-14570, 1999. (Pubitemid 30000690)
29. 123I-labeled AM 251: a radioiodinated ligand which binds in vivo to Mouse brain cannabinoid CB1-receptors. Eur. J. Pharmacol. 307:331-338, 1996. (Pubitemid 26233375)
30. Evans, A.T., Formukong, E.A., and Evans, F.J. Actions of cannabis constitoents on enzmyes of arachidonate metabolism: anti-inflammatory potetial. Biochem. Pharmacol. 36: 2035-2037, 1987. (Pubitemid 17100228)
31. Perez-Reyes, M., Bursyein, S.H., and White, W.R. Antagonism of marihuana effects by indomethacine in humans. Life Sci. 48:507-515, 1991.
32. Green, K., Kearse, E.C., and McIntyre, O.L. Interaction between delta-9-tetrahydrocannabinol and indomethacin. Ophthalmic Res. 33:217-220, 2001. (Pubitemid 32678989)
33. Ocasio, F.M., Jiang, Y., House, S.D., and Chang, S.L. Chronic morphine accelerates the progression of lipopolysaccharideinduced sepsis to septic shock. J. Neuroimmunol. 149:90-100, 2004. (Pubitemid 38352862)
34. Chen, R., Zhou, H., Beltran, J., Malellari, L., and Chang, S.L. Differential expression of cytokines in the brain and serum during endotoxin tolerance. J. Neuroimmunol. 163:53-72, 2005. (Pubitemid 40692949)
35. Greenwood, J., Howes, R., and Lightman, S. The bloodretinasx barrier in experimental uveoretinitis. Leukocyte interactions and functional damage. Lab. Invest. 70:39-52 (1994). (Pubitemid 24080103)
36. 2 receptor mRNA in adult rat retina. Vis. Neurosci. 17:91-95, 2000. (Pubitemid 30167557)
37. Porcella, A., and Maxia, C. The human eye expresses high levels of CB1 cannabinoid receptor mRNA and protein. Eur. J. Neurosci. 12:1123-1127, 2000. (Pubitemid 30168791)
38. Felder, C.C., and Yamamura, H.I. Cannabinoid CB1 expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues. Eur. J. Pharmacol. 431:277-286, 2001. (Pubitemid 33145404)
39. Roche, M., Kelly, J.P., O'Driscoll, M., and Finn, D.P. Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats. Immunology 125:263-271, 2008.
40. Mnich, S.J., Hiebsch, R.R., Huff, R.M., and Muthian, S. Antiinflammatory properties of CB1-receptor antagonist involves beta2 adrenoceptors. J. Pharmacol. Exp. Ther. 333:445-453, 2010.
41. Kasahara, T., Mukaida, N., Yamashita, K., Yagisawa, H., Akahoshi, T., and Matsushima, K. IL-1 and TNF-alpha induction of IL-8 and monocyte chemotactic and activating factor (MCAF) mRNA expression in a human astrocytoma cell line. Immunology 74:60-67, 1991.