Apoptotic markers in semen of infertile men: Association with cigarette smoking

International Braz J Urol

Volumn 37, Issue 4, 2011, Pages 495-506

  El Melegy, Nagla T ^a   Ali, Mohamed Esam M ^a  

^a Faculty of Medicine   (Egypt)

Author keywords

Apoptosis; DNA fragmentation; Infertility; Semen; Smoking

Indexed keywords

BIOLOGICAL MARKER;

ADULT; ANALYSIS OF VARIANCE; APOPTOSIS; ARTICLE; CASE CONTROL STUDY; CHEMISTRY; DNA FRAGMENTATION; GENETICS; HUMAN; MALE; MALE INFERTILITY; NONPARAMETRIC TEST; PHYSIOLOGY; SMOKING; SPERM; SPERMATOZOON MOTILITY; TIME;

ADULT; ANALYSIS OF VARIANCE; APOPTOSIS; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; DNA FRAGMENTATION; HUMANS; INFERTILITY, MALE; MALE; SEMEN; SMOKING; SPERM MOTILITY; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 83455247385     PISSN: 16775538     EISSN: 16776119     Source Type: Journal    
DOI: 10.1590/S1677-55382011000400009     Document Type: Article

References (64)

1. Soares SR, Melo MA: Cigarette smoking and reproductive function. Curr Opin Obstet Gynecol. 2008; 20: 281-91.
2. Caraballo RS, Giovino GA, Pechacek TF, Mowery PD, Richter PA, Strauss WJ, et al.: Racial and ethnic differences in serum cotinine levels of cigarette smokers: Third National Health and Nutrition Examination Survey, 1988-1991. JAMA. 1998; 280: 135-9.
3. Hassan A, Abo-Azma SM, Fayed SM, Mostafa T: Seminal plasma cotinine and insulin-like growth factor-I in idiopathic oligoasthenoteratozoospermic smokers. BJU Int. 2009; 103: 108-11.
4. Arabi M, Moshtaghi H: Influence of cigarette smoking on spermatozoa via seminal plasma. Andrologia. 2005; 37: 119-24.
5. Chen Z, Hauser R, Trbovich AM, Shifren JL, Dorer DJ, Godfrey-Bailey L, et al.: The relationship between human semen characteristics and sperm apoptosis: a pilot study. J Androl. 2006; 27: 112-20.
6. Sinha Hikim AP, Swerdloff RS: Hormonal and genetic control of germ cell apoptosis in the testis. Rev Reprod. 1999; 4: 38-47.
7. Agarwal A, Said TM: Role of sperm chromatin abnormalities and DNA damage in male infertility. Hum Reprod Update. 2003; 9: 331-45.
8. Barroso G, Morshedi M, Oehninger S: Analysis of DNA fragmentation, plasma membrane translocation of phosphatidylserine and oxidative stress in human spermatozoa. Hum Reprod. 2000; 15: 1338-44.
9. Calogero A, Polosa R, Perdichizzi A, Guarino F, La Vignera S, Scarfia A, et al: Cigarette smoke extract immobilizes human spermatozoa and induces sperm apoptosis. Reprod Biomed Online. 2009; 19: 564-71.
10. Lee J, Richburg JH, Younkin SC, Boekelheide K: The Fas system is a key regulator of germ cell apoptosis in the testis. Endocrinology. 1997; 138: 2081-8.
11. Sakkas D, Mariethoz E, St John JC: Abnormal sperm parameters in humans are indicative of an abortive apoptotic mechanism linked to the Fas-mediated pathway. Exp Cell Res. 1999; 251: 350-5.
12. Zedan H, El-Mekhlafi AW, El-Noweihi AM, Abd El-Azim NE, Mostafa T: Soluble Fas and gonadal hormones in infertile men with varicocele. Fertil Steril. 2009; 91: 420-4.
13. Weng SL, Taylor SL, Morshedi M, Schuffner A, Duran EH, Beebe S, et al.: Caspase activity and apoptotic markers in ejaculated human sperm. Mol Hum Reprod. 2002; 8: 984-91.
14. Lozano GM, Bejarano I, Espino J, González D, Ortiz A, García JF, et al.: Relationship between caspase activity and apoptotic markers in human sperm in response to hydrogen peroxide and progesterone. J Reprod Dev. 2009; 55: 615-21.
15. Paasch U, Grunewald S, Fitzl G, Glander HJ: Deterioration of plasma membrane is associated with activated caspases in human spermatozoa. J Androl. 2003; 24: 246-52.
16. World Health Organization. World Health Organization Laboratory Manual for Examination of Human Semen. Cambridge: Cambridge University Press. 1999.
17. Menkveld R, Stander FS, Kotze TJ, Kruger TF, van Zyl JA: The evaluation of morphological characteristics of human spermatozoa according to stricter criteria. Hum Reprod. 1990; 5: 586-92.
18. Perandones CE, Illera VA, Peckham D, Stunz LL, Ashman RF: Regulation of apoptosis in vitro in mature murine spleen T cells. J Immunol. 1993; 151: 3521-9.
19. Cifone MG, De Maria R, Roncaioli P, Rippo MR, Azuma M, Lanier LL, et al.: Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J Exp Med. 1994; 180: 1547-52.
20. Talanian RV, Quinlan C, Trautz S, Hackett MC, Mankovich JA, Banach D, et al.: Substrate specificities of caspase family proteases. J Biol Chem. 1997; 272: 9677-82.
21. Lowery OH, Rosenbrough NJ, Farr AL, Randall RI: rotein measurement with Folin phenol reagent. J Biol Chem. 1951; 193: 265-8.
22. Smith RF, Mather HM, Ellard GA: Assessment of simple colorimetric procedures to determine smoking status of diabetic subjects. Clin Chem. 1998; 44: 275-80.
23. Dorfman SF: Tobacco and fertility: our responsibilities. Fertil Steril. 2008; 89: 502-4.
24. Künzle R, Mueller MD, Hänggi W, Birkhäuser MH, Drescher H, Bersinger NA: Semen quality of male smokers and nonsmokers in infertile couples. Fertil Steril. 2003; 79: 287-91.
25. Ramlau-Hansen CH, Thulstrup AM, Aggerholm AS, Jensen MS, Toft G, Bonde JP: Is smoking a risk factor for decreased semen quality? A cross-sectional analysis. Hum Reprod. 2007; 22: 188-96.
26. Collodel G, Capitani S, Pammolli A, Giannerini V, Geminiani M, Moretti E: Semen quality of male idiopathic infertile smokers and nonsmokers: an ultrastructural study. J Androl. 2010; 31: 108-13.
27. Zavos PM, Correa JR, Antypas S, Zarmakoupis-Zavos PN, Zarmakoupis CN: Effects of seminal plasma from cigarette smokers on sperm viability and longevity. Fertil Steril. 1998; 69: 425-9.
28. Elshal MF, El-Sayed IH, Elsaied MA, El-Masry SA, Kumosani TA: Sperm head defects and disturbances in spermatozoal chromatin and DNA integrities in idiopathic infertile subjects: association with cigarette smoking. Clin Biochem. 2009; 42: 589-94.
29. Sergerie M, Ouhilal S, Bissonnette F, Brodeur J, Bleau G: Lack of association between smoking and DNA fragmentation in the spermatozoa of normal men. Hum Reprod. 2000; 15: 1314-21.
30. Trummer H, Habermann H, Haas J, Pummer K: The impact of cigarette smoking on human semen parameters and hormones. Hum Reprod. 2002; 17: 1554-9.
31. Hassa H, Yildirim A, Can C, Turgut M, Tanir HM, Senses T, et al.: Effect of smoking on semen parameters of men attending an infertility clinic. Clin Exp Obstet Gynecol. 2006; 33: 19-22.
32. Sepaniak S, Forges T, Gerard H, Foliguet B, Bene MC, Monnier-Barbarino P: The influence of cigarette smoking on human sperm quality and DNA fragmentation. Toxicology. 2006; 223: 54-60.
33. Ozgur K, Isikoglu M, Seleker M, Donmez L: Semen quality of smoking and non-smoking men in infertile couples in a Turkish population. Arch Gynecol Obstet. 2005; 271: 109-12.
34. Ramlau-Hansen CH, Thulstrup AM, Storgaard L, Toft G, Olsen J, Bonde JP: Is prenatal exposure to tobacco smoking a cause of poor semen quality? A follow-up study. Am J Epidemiol. 2007; 165: 1372-9.
35. Vermeulen A: Environment, human reproduction, menopause, and andropause. Environ Health Perspect. 1993; 101(Suppl 2): 91-100.
36. Collin O, Kilter S, Bergh A: Tobacco smoke disrupts testicular microcirculation in the rat. Int J Androl. 1995; 18: 141-5. Erratum in: Int J Androl. 1995; 18: 230.
37. Zenzes MT: Smoking and reproduction: gene damage to human gametes and embryos. Hum Reprod Update. 2000; 6: 122-31.
38. Kumosani TA, Elshal MF, Al-Jonaid AA, Abduljabar HS: The influence of smoking on semen quality, seminal microelements and Ca2+-ATPase activity among infertile and fertile men. Clin Biochem. 2008; 41: 1199-203.
39. Horak S, Polanska J, Widlak P: Bulky DNA adducts in human sperm: relationship with fertility, semen quality, smoking, and environmental factors. Mutat Res. 2003; 537: 53-65.
40. Saleh RA, Agarwal A, Nelson DR, Nada EA, El-Tonsy MH, Alvarez JG, et al.: Increased sperm nuclear DNA damage in normozoospermic infertile men: a prospective study. Fertil Steril. 2002; 78: 313-8.
41. Pasqualotto FF, Umezu FM, Salvador M, Borges E Jr, Sobreiro BP, Pasqualotto EB: Effect of cigarette smoking on antioxidant levels and presence of leukocytospermia in infertile men: a prospective study. Fertil Steril. 2008; 90: 278-83.
42. Sailer BL, Jost LK, Evenson DP: Mammalian sperm DNA susceptibility to in situ denaturation associated with the presence of DNA strand breaks as measured by the terminal deoxynucleotidyl transferase assay. J Androl. 1995; 16: 80-7.
43. Aitken RJ, Gordon E, Harkiss D, Twigg JP, Milne P, Jennings Z, et al.: Relative impact of oxidative stress on the functional competence and genomic integrity of human spermatozoa. Biol Reprod. 1998; 59: 1037-46.
44. Evenson DP, Wixon R: Clinical aspects of sperm DNA fragmentation detection and male infertility. Theriogenology. 2006; 65: 979-91.
45. Sun JG, Jurisicova A, Casper RF: Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol Reprod. 1997; 56: 602-7.
46. Irvine DS, Twigg JP, Gordon EL, Fulton N, Milne PA, Aitken RJ: DNA integrity in human spermatozoa: relationships with semen quality. J Androl. 2000; 21: 33-44.
47. Mahfouz RZ, Sharma RK, Said TM, Erenpreiss J, Agarwal A: Association of sperm apoptosis and DNA ploidy with sperm chromatin quality in human spermatozoa. Fertil Steril. 2009; 91: 1110-8.
48. Chan PJ, Corselli JU, Patton WC, Jacobson JD, Chan SR, King A: A simple comet assay for archived sperm correlates DNA fragmentation to reduced hyperactivation and penetration of zona-free hamster oocytes. Fertil Steril. 2001; 75: 186-92.
49. Saleh RA, Agarwal A, Nada EA, El-Tonsy MH, Sharma RK, Meyer A,vet al.: Negative effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility. Fertil Steril. 2003; 79(Suppl 3): 1597-605.
50. Zenzes MT, Bielecki R, Reed TE: Detection of benzo(a)pyrene diol epoxide-DNA adducts in sperm of men exposed to cigarette smoke. Fertil Steril. 1999; 72: 330-5.
51. Cayli S, Sakkas D, Vigue L, Demir R, Huszar G: Cellular maturity and apoptosis in human sperm: creatine kinase, caspase-3 and Bcl-XL levels in mature and diminished maturity sperm. Mol Hum Reprod. 2004; 10: 365-72.
52. Fujisawa M, Ishikawa T: Soluble forms of Fas and Fas ligand concentrations in the seminal plasma of infertile men with varicocele. J Urol. 2003; 170: 2363-5.
53. Sakkas D, Moffatt O, Manicardi GC, Mariethoz E, Tarozzi N, Bizzaro D: Nature of DNA damage in ejaculated human spermatozoa and the possible involvement of apoptosis. Biol Reprod. 2002; 66: 1061-7.
54. Pentikäinen V, Erkkilä K, Dunkel L: Fas regulates germ cell apoptosis in the human testis in vitro. Am J Physiol. 1999; 276: E310-6.
55. Marchetti C, Gallego MA, Defossez A, Formstecher P, Marchetti P: Staining of human sperm with fluorochrome-labeled inhibitor of caspases to detect activated caspases: correlation with apoptosis and sperm parameters. Hum Reprod. 2004; 19: 1127-34.
56. Almeida C, Cardoso MF, Sousa M, Viana P, Gonçalves A, Silva J, et al.: Quantitative study of caspase-3 activity in semen and after swim-up preparation in relation to sperm quality. Hum Reprod. 2005; 20: 1307-13.
57. Centola GM, Eberly S: Seasonal variations and agerelated changes in human sperm count, motility, motion parameters, morphology, and white blood cell concentration. Fertil Steril. 1999; 72: 803-8.
58. Kidd SA, Eskenazi B, Wyrobek AJ: Effects of male age on semen quality and fertility: a review of the literature. Fertil Steril. 2001; 75: 237-48.
59. Levitas E, Lunenfeld E, Weisz N, Friger M, Potashnik G: Relationship between age and semen parameters in men with normal sperm concentration: analysis of 6022 semen samples. Andrologia. 2007; 39: 45-50.
60. Mukhopadhyay D, Varghese AC, Pal M, Banerjee SK, Bhattacharyya AK, Sharma RK, et al.: Semen quality and age-specific changes: a study between two decades on 3,729 male partners of couples with normal sperm count and attending an andrology laboratory for infertility-related problems in an Indian city. Fertil Steril. 2010; 93: 2247-54.
61. Chen Z, Godfrey-Bailey L, Schiff I, Hauser R: Impact of seasonal variation, age and smoking status on human semen parameters: The Massachusetts General Hospital experience. J Exp Clin Assist Reprod. 2004; 1: 2.
62. Winkle T, Rosenbusch B, Gagsteiger F, Paiss T, Zoller N: The correlation between male age, sperm quality and sperm DNA fragmentation in 320 men attending a fertility center. J Assist Reprod Genet. 2009; 26: 41-6.
63. Chen Z, Toth T, Godfrey-Bailey L, Mercedat N, Schiff I, Hauser R: Seasonal variation and age-related changes in human semen parameters. J Androl. 2003; 24: 226-31.
64. Gandini L, Lombardo F, Paoli D, Caponecchia L, Familiari G, Verlengia C, et al.: Study of apoptotic DNA fragmentation in human spermatozoa. Hum Reprod. 2000; 15: 830-9.