Somatic alterations in mitochondrial DNA produce changes in cell growth and metabolism supporting a tumorigenic phenotype

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1822, Issue 2, 2012, Pages 293-300

  Jandova, Jana ^a   Shi, Mingjian ^b   Norman, Kimberly G ^b   Stricklin, George P ^b   Sligh, James E ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antioxidants; Migration and invasion; MtDNA mutation; Proliferation; Reactive oxygen species; UV induced apoptosis

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; CELL NUCLEUS DNA; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

ALLELE; ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL GROWTH; CELL INVASION; CELL METABOLISM; CELL MIGRATION; CELL PROLIFERATION; CELL RESPIRATION; CELL TRANSFER; CONTROLLED STUDY; GENE LOCUS; GENOTYPE; HAPLOTYPE; HYBRID CELL; LOCUS CERULEUS; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SOMATIC CELL; SOMATIC MUTATION; ULTRAVIOLET A RADIATION;

ALLELES; ALLELIC IMBALANCE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; ARGININE; CELL LINE; CELL MOVEMENT; CELL NUCLEUS; CELL PROLIFERATION; CELL RESPIRATION; CELL TRANSFORMATION, NEOPLASTIC; DNA, MITOCHONDRIAL; GENETIC LOCI; GENETIC VARIATION; HAPLOTYPES; HYBRID CELLS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MITOCHONDRIA; MUTATION; NEOPLASM INVASIVENESS; PHENOTYPE; RNA, TRANSFER;

MUS MUSCULUS;

EID: 83455245373     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2011.11.010     Document Type: Article

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