Antisense knockdown of Kras inhibits fibrosis in a rat model of unilateral ureteric obstruction

American Journal of Pathology

Volumn 180, Issue 1, 2012, Pages 82-90

  Wang, Jia Hui ^a   Newbury, Lucy J ^a   Knisely, A S ^b   Monia, Brett ^c   Hendry, Bruce M ^a   Sharpe, Claire C ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING S COLLEGE HOSPITAL   (United Kingdom)

^c ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTISENSE OLIGONUCLEOTIDE; COLLAGEN TYPE 1; K RAS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FIBROBLAST; GENE SILENCING; GENE THERAPY; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY FIBROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; URETER OBSTRUCTION; WESTERN BLOTTING;

ACTINS; ANIMALS; CELLS, CULTURED; FIBROSIS; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; MALE; NEPHRITIS; OLIGONUCLEOTIDES, ANTISENSE; PROTO-ONCOGENE PROTEINS P21(RAS); RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; URETER; URETERAL OBSTRUCTION;

EID: 83455228625     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.09.036     Document Type: Article

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