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Volumn 75, Issue 1, 2012, Pages 1-4

The 2011 Nobel Prize in physiology or medicine

Author keywords

[No Author keywords available]

Indexed keywords

CANCER VACCINE; PROVENGE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AGONIST;

EID: 83455224662     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2011.02663.x     Document Type: Article
Times cited : (21)

References (37)
  • 1
    • 83455175970 scopus 로고    scopus 로고
    • The 2011 Nobel Prize in Physiology or Medicine - Press Release. URL: (Accessed on 1 November 2011)
    • The 2011 Nobel Prize in Physiology or Medicine - Press Release. URL: (Accessed on 1 November 2011), 2011.
    • (2011)
  • 2
    • 80053064918 scopus 로고    scopus 로고
    • Toward a modern synthesis of immunity: Charles A. Janeway Jr. and the immunologist's dirty little secret
    • Gayed PM. Toward a modern synthesis of immunity: Charles A. Janeway Jr. and the immunologist's dirty little secret. Yale J Biol Med 2011;84:131-8.
    • (2011) Yale J Biol Med , vol.84 , pp. 131-138
    • Gayed, P.M.1
  • 3
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway CA Jr. Approaching the asymptote? Evolution and revolution in immunology Cold Spring Harb Symp Quant Biol 1989;54 (Pt 1):1-13.
    • (1989) Cold Spring Harb Symp Quant Biol , vol.54 , Issue.PART 1 , pp. 1-13
    • Janeway Jr, C.A.1
  • 4
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996;86:973-83.
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.M.4    Hoffmann, J.A.5
  • 5
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in Drosophila
    • Nusslein-Volhard C, Wieschaus E. Mutations affecting segment number and polarity in Drosophila. Nature 1980;287:795-801.
    • (1980) Nature , vol.287 , pp. 795-801
    • Nusslein-Volhard, C.1    Wieschaus, E.2
  • 6
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997;388:394-7.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr, C.A.3
  • 7
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
    • Poltorak A, He X, Smirnova I et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998;282:2085-8.
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1    He, X.2    Smirnova, I.3
  • 8
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: critical proteins linking innate and acquired immunity
    • Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001;2:675-80.
    • (2001) Nat Immunol , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 9
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001;1:135-45.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 10
    • 29244450802 scopus 로고    scopus 로고
    • Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
    • Barton GM, Kagan JC, Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat Immunol 2006;7:49-56.
    • (2006) Nat Immunol , vol.7 , pp. 49-56
    • Barton, G.M.1    Kagan, J.C.2    Medzhitov, R.3
  • 11
    • 34948862264 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
    • Lande R, Gregorio J, Facchinetti V et al. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature 2007;449:564-9.
    • (2007) Nature , vol.449 , pp. 564-569
    • Lande, R.1    Gregorio, J.2    Facchinetti, V.3
  • 12
    • 0036008014 scopus 로고    scopus 로고
    • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
    • Hemmi H, Kaisho T, Takeuchi O et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 2002;3:196-200.
    • (2002) Nat Immunol , vol.3 , pp. 196-200
    • Hemmi, H.1    Kaisho, T.2    Takeuchi, O.3
  • 13
    • 53849109907 scopus 로고    scopus 로고
    • Putting endotoxin to work for us: monophosphoryl lipid A as a safe and effective vaccine adjuvant
    • Casella CR, Mitchell TC. Putting endotoxin to work for us: monophosphoryl lipid A as a safe and effective vaccine adjuvant. Cell Mol Life Sci 2008;65:3231-40.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3231-3240
    • Casella, C.R.1    Mitchell, T.C.2
  • 14
    • 80051814602 scopus 로고    scopus 로고
    • Targeting of Toll-like receptors: a decade of progress in combating infectious diseases
    • Hedayat M, Netea MG, Rezaei N. Targeting of Toll-like receptors: a decade of progress in combating infectious diseases. Lancet Infect Dis 2011;11:702-12.
    • (2011) Lancet Infect Dis , vol.11 , pp. 702-712
    • Hedayat, M.1    Netea, M.G.2    Rezaei, N.3
  • 15
    • 0015949926 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice. II. Functional properties in vitro
    • Steinman RM, Cohn ZA. Identification of a novel cell type in peripheral lymphoid organs of mice. II. Functional properties in vitro. J Exp Med 1974;139:380-97.
    • (1974) J Exp Med , vol.139 , pp. 380-397
    • Steinman, R.M.1    Cohn, Z.A.2
  • 16
    • 0015619335 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution
    • Steinman RM, Cohn ZA. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J Exp Med 1973;137:1142-62.
    • (1973) J Exp Med , vol.137 , pp. 1142-1162
    • Steinman, R.M.1    Cohn, Z.A.2
  • 17
    • 34447605625 scopus 로고
    • Ueber die Nerven der menschlichen Haut
    • Langerhans P. Ueber die Nerven der menschlichen Haut. Virchows Arch 1868;44:325-37.
    • (1868) Virchows Arch , vol.44 , pp. 325-337
    • Langerhans, P.1
  • 18
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998;392:245-52.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 19
    • 0030781916 scopus 로고    scopus 로고
    • Dendritic cells: unique leukocyte populations which control the primary immune response
    • Hart DN. Dendritic cells: unique leukocyte populations which control the primary immune response. Blood 1997;90:3245-87.
    • (1997) Blood , vol.90 , pp. 3245-3287
    • Hart, D.N.1
  • 20
    • 46749150611 scopus 로고    scopus 로고
    • Demystifying the development of dendritic cell subtypes, a little
    • Naik SH. Demystifying the development of dendritic cell subtypes, a little. Immunol Cell Biol 2008;86:439-52.
    • (2008) Immunol Cell Biol , vol.86 , pp. 439-452
    • Naik, S.H.1
  • 23
    • 0034614886 scopus 로고    scopus 로고
    • The induction of tolerance by dendritic cells that have captured apoptotic cells
    • Steinman RM, Turley S, Mellman I, Inaba K. The induction of tolerance by dendritic cells that have captured apoptotic cells. J Exp Med 2000;191:411-6.
    • (2000) J Exp Med , vol.191 , pp. 411-416
    • Steinman, R.M.1    Turley, S.2    Mellman, I.3    Inaba, K.4
  • 24
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance
    • Steinman RM, Nussenzweig MC. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc Natl Acad Sci U S A 2002;99:351-8.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 351-358
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 26
    • 33644502594 scopus 로고    scopus 로고
    • Dendritic cell apoptosis in the maintenance of immune tolerance
    • Chen M, Wang YH, Wang Y et al. Dendritic cell apoptosis in the maintenance of immune tolerance. Science 2006;311:1160-4.
    • (2006) Science , vol.311 , pp. 1160-1164
    • Chen, M.1    Wang, Y.H.2    Wang, Y.3
  • 28
    • 79955537167 scopus 로고    scopus 로고
    • IFN-alpha production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes is promoted by NK cells via MIP-1beta and LFA-1
    • Hagberg N, Berggren O, Leonard D et al. IFN-alpha production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes is promoted by NK cells via MIP-1beta and LFA-1. J Immunol 2011;186:5085-94.
    • (2011) J Immunol , vol.186 , pp. 5085-5094
    • Hagberg, N.1    Berggren, O.2    Leonard, D.3
  • 30
    • 0029961746 scopus 로고    scopus 로고
    • CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells
    • Zhou LJ, Tedder TF. CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc Natl Acad Sci USA 1996;93:2588-92.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2588-2592
    • Zhou, L.J.1    Tedder, T.F.2
  • 31
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
    • Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 1994;179:1109-18.
    • (1994) J Exp Med , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 32
    • 17144417748 scopus 로고    scopus 로고
    • Dendritic cells as therapeutic vaccines against cancer
    • Banchereau J, Palucka AK. Dendritic cells as therapeutic vaccines against cancer. Nat Rev Immunol 2005;5:296-306.
    • (2005) Nat Rev Immunol , vol.5 , pp. 296-306
    • Banchereau, J.1    Palucka, A.K.2
  • 33
    • 34248204110 scopus 로고    scopus 로고
    • DC-based cancer vaccines
    • Gilboa E. DC-based cancer vaccines. J Clin Invest 2007;117:1195-203.
    • (2007) J Clin Invest , vol.117 , pp. 1195-1203
    • Gilboa, E.1
  • 34
    • 34848837386 scopus 로고    scopus 로고
    • Taking dendritic cells into medicine
    • Steinman RM, Banchereau J. Taking dendritic cells into medicine. Nature 2007;449:419-26.
    • (2007) Nature , vol.449 , pp. 419-426
    • Steinman, R.M.1    Banchereau, J.2
  • 35
    • 78149236593 scopus 로고    scopus 로고
    • The first dendritic cell-based therapeutic cancer vaccine is approved by the FDA
    • Hovden AO, Appel S. The first dendritic cell-based therapeutic cancer vaccine is approved by the FDA. Scand J Immunol 2010;72:554.
    • (2010) Scand J Immunol , vol.72 , pp. 554
    • Hovden, A.O.1    Appel, S.2
  • 36
    • 34948895988 scopus 로고    scopus 로고
    • Lasker Basic Medical Research Award. Dendritic cells: versatile controllers of the immune system
    • Steinman RM. Lasker Basic Medical Research Award. Dendritic cells: versatile controllers of the immune system. Nat Med 2007;13:1155-9.
    • (2007) Nat Med , vol.13 , pp. 1155-1159
    • Steinman, R.M.1
  • 37
    • 80053601131 scopus 로고    scopus 로고
    • Nobel Prize in physiology or medicine. Immunology prize overshadowed by untimely death of awardee
    • Travis J. Nobel Prize in physiology or medicine. Immunology prize overshadowed by untimely death of awardee. Science 2011;334:31.
    • (2011) Science , vol.334 , pp. 31
    • Travis, J.1


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