Film coated tablets (ColoPulse technology) for targeted delivery in the lower intestinal tract: Influence of the core composition on release characteristics

Pharmaceutical Development and Technology

Volumn 17, Issue 1, 2012, Pages 40-47

  Schellekens, Reinout C A ^a,b   Baltink, Jan H ^b   Woesthuis, Ellen M ^b   Stellaard, Frans ^a   Kosterink, Jos G W ^a   Woerdenbag, Herman J ^b   Frijlink, Henderik W ^b  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Colon delivery; Disintegration; Film coating; Mesalazine; Pulsatile delivery; Water uptake

Indexed keywords

ALPHA LACTOSE; BENZOIC ACID; BICARBONATE; CELLULOSE; CITRIC ACID; COPPER SULFATE; CROSCARMELLOSE SODIUM; EUDRAGIT; GLUCOSE; MAGNESIUM STEARATE; MESALAZINE; MICROCRYSTALLINE CELLULOSE; POVIDONE; SILICON DIOXIDE; STARCH GLYCOLATE SODIUM;

ARTICLE; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; DRUG RELEASE; FILM COATING; INTESTINE; MEDICAL TECHNOLOGY; PRIORITY JOURNAL; TABLET DISINTEGRATION; WATER TRANSPORT;

ALGORITHMS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEMISTRY, PHARMACEUTICAL; COLON; COLOR; DRUG DELIVERY SYSTEMS; EXCIPIENTS; HARDNESS; HUMANS; HYDROGEN-ION CONCENTRATION; LOWER GASTROINTESTINAL TRACT; MESALAMINE; PHARMACEUTICAL PREPARATIONS; POLYMETHACRYLIC ACIDS; REPRODUCIBILITY OF RESULTS; SOLUBILITY; SUSPENSIONS; TABLETS, ENTERIC-COATED;

EID: 83455220795     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2010.513986     Document Type: Article

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