In vitro and in vivo evaluation of guar gum-based matrix tablets of rofecoxib for colonic drug delivery

Current Drug Delivery

Volumn 2, Issue 2, 2005, Pages 155-163

  Al Saidan, S M ^a   Krishnaiah, Y S R ^a   Satyanarayana, V ^b   Rao, G S ^c  

^a KUWAIT UNIVERSITY   (Kuwait)

^b Sipra Labs Pvt Ltd   (India)

^c ANDHRA UNIVERSITY   (India)

Author keywords

Colonic drug delivery; Evaluation; Guar gum; Matrix tablets; Rofecoxib

Indexed keywords

GUAR GUM; NIMESULIDE; ROFECOXIB; TINIDAZOLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CANCER PREVENTION; CHEMOPROPHYLAXIS; CLINICAL TRIAL; COLON ABSORPTION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE TIME EFFECT RELATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG GRANULATION; DRUG RELEASE; DRUG SOLUBILITY; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; RAT; SMALL INTESTINE; STOMACH; TABLET FORMULATION; TABLET MATRIX; WET GRANULATION;

ADOLESCENT; ADULT; COLON; COLORECTAL NEOPLASMS; DRUG DELIVERY SYSTEMS; GALACTANS; HUMANS; LACTONES; MANNANS; PLANT GUMS; SOLUBILITY; SULFONES; TABLETS;

EID: 16844376491     PISSN: 15672018     EISSN: None     Source Type: Journal    
DOI: 10.2174/1567201053586010     Document Type: Article

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