Reconstitution of KCNE1 into lipid bilayers: Comparing the structural, dynamic, and activity differences in micelle and vesicle environments

Biochemistry

Volumn 50, Issue 50, 2011, Pages 10851-10859

  Coey, Aaron T ^a   Sahu, Indra D ^a   Gunasekera, Thusitha S ^a   Troxel, Kaylee R ^a   Hawn, Jaclyn M ^a   Swartz, Max S ^a   Wickenheiser, Marilyn R ^a   Reid, Ro Jay ^a   Welch, Richard C ^b   Vanoye, Carlos G ^b   Kang, Congbao ^b   Sanders, Charles R ^b   Lorigan, Gary A ^a  

^a MIAMI UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELICITIES; HUMAN HEART; KEY COMPONENT; LIPID VESICLES; LIPID-BILAYER VESICLES; LOCAL STRUCTURE; MICELLE SOLUTION; MICRO-INJECTION; NATIVE STRUCTURES; PROTEOLIPOSOMES; SODIUM SALT; SPECTROSCOPIC TECHNIQUE; STRUCTURAL STUDIES; TRANS-MEMBRANE PROTEINS; VOLTAGE-GATED POTASSIUM CHANNELS; XENOPUS OOCYTE;

AMINO ACIDS; CIRCULAR DICHROISM SPECTROSCOPY; DICHROISM; ELECTRON SPIN RESONANCE SPECTROSCOPY; GLYCEROL; MICELLES; PARAMAGNETIC RESONANCE; PARAMAGNETISM; PHOSPHOLIPIDS; PROTEINS; REFINING; SALTS;

LIPID BILAYERS;

2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; LEUCINE; PHENYLALANINE; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KCNQ1; SERINE; SODIUM;

ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; LIPID BILAYER; LIPID VESICLE; MEMBRANE RECONSTITUTION; MICELLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEOLIPOSOME; XENOPUS;

ANIMALS; CELL MEMBRANE; CIRCULAR DICHROISM; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; LIPID BILAYERS; LIPOSOMES; MICELLES; MICROINJECTIONS; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; OOCYTES; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLGLYCEROLS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; XENOPUS LAEVIS;

EID: 83455213894     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2009294     Document Type: Article

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