Alpha and theta rhythm abnormality in Alzheimer's disease: A study using a computational model

Advances in Experimental Medicine and Biology

Volumn 718, Issue , 2011, Pages 57-73

  Bhattacharya, Basabdatta Sen ^a   Coyle, Damien ^a   Maguire, Liam P ^a  

^a UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA RHYTHM; ALZHEIMER DISEASE; BRAIN FUNCTION; CELL MEMBRANE POTENTIAL; CELL POPULATION; CONFERENCE PAPER; EXCITATORY POSTSYNAPTIC POTENTIAL; FEEDBACK SYSTEM; HUMAN; INHIBITORY POSTSYNAPTIC POTENTIAL; MATHEMATICAL MODEL; NONHUMAN; OSCILLATORY POTENTIAL; PRIORITY JOURNAL; SENSORY NERVE CELL; SENSORY NERVE CONDUCTION; SPIKE WAVE; THETA RHYTHM;

ALZHEIMER DISEASE; COMPUTER SIMULATION; ELECTROENCEPHALOGRAPHY; HUMANS;

EID: 83455196103     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-0164-3_6     Document Type: Conference Paper

References (49)

1. Basar, E., Guntekin, B.: A review of brain oscillations in cognitive disorders and the role of neurotransmitters. Brain Res. 1235, 172-193 (2008)
2. Basar, E., Schurmann, M., Basar-Eroglu, C., Karakas, S.: Alpha oscillations in brain functioning: an integrative theory. Int. J. Psychophysiol. 26, 5-29 (1997)
3. Bennys, K., Rondouin, G., Vergnes, C., Touchon, J.: Diagnostic value of quantitative EEG in Azheimers Disease. Clin. Neurophysiol. 31, 153-160 (2001)
4. Bhattacharya, B.S., Coyle, D., Maguire, L.P.: A computational modelling approach to investigate alpha rhythm slowing associated with Alzheimers Disease. In: Proceedings of the Conference on Brain Inspired Cognitive Systems (BICS), Madrid, Spain, pp. 382-392 (2010)
5. Bhattacharya, B.S., Coyle, D., Maguire, L.P.: Intra- and inter-connectivity influences on event related changes in thalamocortical alpha rhythms. In: Proceedings of the conference on Biologically-Inspired Computation: Theories and Applications (BIC-TA), Liverpool, United Kingdom, pp. 1685-1692 (2010). ISBN 978-1-4244-6439-5
6. Bhattacharya, B.S., Coyle, D., Maguire, L.P.: Thalamocortical circuitry and alpha rhythm slowing: an empirical study based on a classic computational model. In: Proceedings of the International Joint Conference on Neural Networks (IJCNN), Barcelona, Spain, pp. 3912-3918 (2010)
7. Brenner, R.P., Reynolds, C.F., Ulrich, R.F.: Diagnostic efficacy of computerized spectral versus visual EEG analysis in elderly normal, demented and depressed subjects. Electroencephalogr. Clin. Neurophysiol. 69, 110-117 (1988)
8. Brenner, R.P., Reynolds, C.F., Ulrich, R.F.: EEG findings in depressive pseudodementia and dementia with secondary depression. Electroencephalogr. Clin. Neurophysiol. 72, 298-304 (1989)
9. Brenner, R.P., Ulrich, R.F., Spiker, D.G., Sclabassi, R.J., Reynolds, C.F., Marin, R.S., Boller, F.: Computerized EEG spectral analysis in elderly normal, demented and depressed subjects. Electroencephalogr. Clin. Neurophysiol. 64, 483-492 (1986)
10. Cantero, J.L., Atienza, M., Gomez-Herrero, G., Cruz-Vadell, A., Gil-Neciga, E., Rodriguez-Romero, R., Garcia- Solis, D.: Functional integrity of thalamocortical circuits differentiates normal ageing from mild cognitive impairment. Hum. Brain Mapp. 30, 3944-3957 (2009)
11. Stam, C.J., Pijn, J.P.M., Suffczýnski, P., da Silva, F.H.L.: Dynamics of the human alpha rhythm: evidence for non-linearity? Clin. Neurophysiol. 110, 1801-1813 (1999)
12. Cummings, J.L., Vinters, H.V., Cole, G.M., Khachaturian, Z.S.: Alzheimers Disease: Etiologies, pathophysiology, cognitive reserve, and treatment opportunities. Neurology 51(Suppl 1), 2-17 (1998)
13. Siemers, E.M.: Advances in biomarkers and modelling for the development of improved therapeutics: early Alzheimers treatment. Abstract of talk at: 1st International Congress on Alzheimers Disease and Advanced Neurotechnologies (2010)
14. Geula, C.: Abnormalities of neural circuitry in Alzheimers Disease. Neurology 51(Suppl 1), 18-29 (1998)
15. Hogan, M., Swanwick, G.R.J., Kaiser, J., Rowan, M., Lawlor, B.: Memory-related EEG power and coherence reductions in mild Alzheimers Disease. Int. J. Psychophysiol. 49, 147-163 (2003)
16. Hughes, S.W., Crunelli, V.: Thalamocortical mechanisms in EEG alpha rhythms and their pathological implications. The Neuroscientist 11(4), 357-372 (2005)
17. Hughes, S.W., Lorincz, M., Cope, D.W., Blethyn, K.L., Kekesi, K.A., Parri, H.R., Juhasz, G., Crunelli, V.: Synchronised oscillations at and frequencies in the Lateral Geniculate Nucleus. Neuron 42, 253-268 (2004)
18. Izhikevich, E.M., Edelman, G.M.: Large-scale model of mammalian thalamocortical systems. Proc. Natl. Acad. Sci. USA 105(9), 3593-3598 (2008)
19. Jeong, J.: EEG dynamics in patients with Alzheimers disease. Clin. Neurophysiol. 115, 1490-1505 (2004)
20. Jones, E.G.: The Thalamus, Vols. I and II, 1st edn. Cambridge University Press, Cambridge (2007)
21. Kim, U., Sanchez-Vives, M.V., McCormick, D.A.: Functional dynamics of gabaergic inhibition in the thalamus. Science 278, 130-134 (1997)
22. Llinas, R.: The intrinsic electrophysiological properties ofmammalian neurons: insights into central nervous system function. Science 242, 1654-1664 (1988)
23. McCormick, D.A.: Acetylcholine: distribution, receptors, and action, pp. 91-101 (1989)
24. McCormick, D.A., Bal, T.: Sleep and arousal: thalamocortical mechanisms. Annu. Rev. Neurosci. 20, 185-215 (1997)
25. Montez, T., Poil, S.S., Jones, B.F., Manshanden, I., Verbunt, J.P., van Dijk, B.W., Brussaard, A.B., van Ooyen, A., Stam, C.J., Scheltens, P., Linkenkaer-Hansen, K.: Altered temporal correlations in parietal alpha and prefrontal theta oscillations in early-stage Alzheimers Disease. Proc. Natl. Acad. Sci. USA 106(5), 1614-1619 (2009)
26. Niedermeyer, E.: Alpha rhythms as physiological and abnormal phenomena. Int. J. Psychophysiol. 26, 31-49 (1997)
27. Prinz, P.N., Vitiello, M.V.: Dominant occipital (alpha) rhythm frequency in early stage Alzheimers Disease and depression. Electroencephalogr. Clin. Neurophysiol. 73, 427-432 (1989)
28. Raji, C.A., Lopez, O.L., Kuller, L.H., Carmichael, O.T., Becker, J.T.: Age, Alzheimer Disease, and brain structure. Neurology 73, 1899-1905 (2009)
29. Rodrigues, S., Chizhov, A.V., Marten, F., Terry, J.R.: Mappings between a macroscopic neural-mass model and a reduced conductance-based model. NeuroImage 102, 361-371 (2010)
30. Romei, V., et al.: On the role of prestimulus alpha rhythms over occipito-parietal areas in visual input regulation: correlation or causation? J. Neurosci. 30, 8692-8697 (2010)
31. Schreckenberger, M., Lange-Asschenfeld, C., Lochmann, M., Mann, K., Siessmeier, T., Buchholz, H.-G., Bartenstein, P., Gründer, G.: The thalamus as the generator and modulator of EEG alpha rhythm: a combined PET/EEG study with lorazepam challenge in humans. NeuroImage 22(2), 637-644 (2004)
32. Sherman, S.M.: Thalamus. Scholarpedia 1(9), 1583 (2006)
33. Sherman, S.M., Guillery, R.W.: Exploring the Thalamus, 1st edn. Academic Press, New York (2001)
34. da Silva, F.H.L.: Neural mechanisms underlying brain waves: from neural membranes to networks. Electroencephalogr. Clin. Neurophysiol. 79, 81-93 (1991)
35. da Silva, F.H.L., van Lierop, T.H.M.T., Schrijer, C.F., van Leeuwen, W.S.: Essential differences between alpha rhythms and barbiturate spindles: spectra and thalamo-cortical coherences. Electroencephalogr. Clin. Neurophysiol. 35, 641-645 (1973)
36. Soininen, H., Reinikainen, K., Partanen, J., Helkala, E.-L., Paljärvi, L., Riekkinen, P. Sr.: Slowing of electroencephalogram and choline acetyltransferase activity in post mortem frontal cortex in definite Alzheimers Disease. Neuroscience 49(3), 529-535 (1992)
37. Soininen, H., Reinikainen, K., Partanen, J., Mervaala, E., Paljarvi, L., Helkala, E.-L., Riekkinen, P. Sr.: Slowing of the dominant occipital rhythm in electroencephalogram is associated with low concentration of noradrenaline in the thalamus in patients with Alzheimers disease. Neurosci. Lett. 137, 5-8 (1992)
38. Stam, C.J.: Use of magnetoencephalography (MEG) to study functional brain networks in neurodegenerative disorders. J. Neurolog. Sci. 289, 128-134 (2010)
39. Suffczýnski, P.: Neural dynamics underlying brain thalamic oscillations investigated with computational models. Ph.D. thesis, Institute of Experimental Physics, University of Warsaw (October 2000)
40. Suffczýnski, P., et al.: Event-related dynamics of alpha rhythms: a neuronal network model of focal ERD/surround ERS. In: Pfurtscheller, G., da Silva, F.H.L. (eds.) Handbook of Electroencephalography and Clinical Neurophysiology, Revised series, pp. 67-85. Elsevier, Amsterdam (1999)
41. Tombol, T.: Short neurons and their synaptic relations in the specific thalamic nuclei. Brain Res. 3, 307-326 (1967)
42. Tourtellotte, W.G., Hoesen, G.W.V., Hyman, B.T., Tikoo, R.K., Damasio, A.R.: Afferents of the thalamic reticular nucleus are pathologically altered in Alzheimers Disease. J. Neuropathol. Exp. Neurol. 48(3), 336 (1989)
43. Uhlhaas, P.J., Pantel, J., Lanfermann, H., Prvulovic, D., Haenschel, C., Maurer, K., Linden, D.E.J.: Visual perceptual organization deficits in Alzheimers dementia. Dement. Geriatr. Cogn. Disord. 25(5), 465-475 (2008)
44. Ursino, M., Cona, F., Zavaglia, M.: The generation of rhythms within a cortical region: Analysis of a neural mass model. NeuroImage 52(3), 1080-1094 (2010)
45. Wada, Y., Nanbu, Y., Jiang, Z.-Y., Koshino, Y., Yamaguchi, N., Hashimoto, T.: Electroencephalographic abnormalities in patients with presenile dementia of the Alzheimer type: quantitative analysis at rest and during photic stimulation. Biol. Psychiatry 41, 217-225 (1997)
46. Waugh, W.H.: A call to reduce the incidence of Alzheimers Disease. J. Appl. Res. 10(2), 53-57 (2010)
47. Wilson, H.R., Cowan, J.D.: Excitatory and inhibitory interaction in localized populations of model neurons. J. Biophys. 12, 1-23 (1972)
48. Wilson, H.R., Cowan, J.D.: A mathematical theory of the functional dynamics of cortical and thalamic nervous tissue. Kybernetik 13, 55-80 (1973)
49. Zetterberg, L.H., Kristiansson, L., Mossberg, K.: Performance of a model for a local neuron population. Biol. Cybern. 31, 15-26 (1978)