Early short-term treatment with doxycycline modulates postinfarction left ventricular remodeling

Circulation

Volumn 108, Issue 12, 2003, Pages 1487-1492

  Villarreal, Francisco J ^a   Griffin, Michael ^b   Omens, Jeffrey ^b   Dillmann, Wolfgang ^b   Nguyen, Judy ^b   Covell, James ^b  

^a UCSD MEDICAL CENTER   (United States)

^b NONE

Author keywords

Collagen; Infarction; Metalloproteinases; Remodeling

Indexed keywords

COLLAGEN; DOXYCYCLINE; FLUORESCENT DYE; METALLOPROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVATION; EPICARDIUM; EXTRACELLULAR MATRIX; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; HEART WEIGHT; HEMODYNAMICS; MALE; NONHUMAN; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; RAT; SCAR; SHORT COURSE THERAPY; STRESS STRAIN RELATIONSHIP; STRUCTURE ACTIVITY RELATION; SYSTOLIC BLOOD PRESSURE;

ANIMALS; BODY WEIGHT; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DOXYCYCLINE; DRUG ADMINISTRATION SCHEDULE; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; HEART; HEMODYNAMIC PROCESSES; MALE; MATRIX METALLOPROTEINASES; MYOCARDIAL INFARCTION; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 0141839055     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000089090.05757.34     Document Type: Article

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