An efficient high-throughput screening method for MYST family acetyltransferases, a new class of epigenetic drug targets

Journal of Biomolecular Screening

Volumn 16, Issue 10, 2011, Pages 1196-1205

  Falk, Hendrik ^a,b,c   Connor, Theresa ^a   Yang, Hong ^a,c   Loft, Karen J ^a,c   Alcindor, Joanne L ^a,b,c   Nikolakopoulos, George ^a,b,c   Surjadi, Regina N ^d   Bentley, John D ^d   Hattarki, Meghan K ^d   Dolezal, Olan ^d   Murphy, James M ^a,b   Monahan, Brendon J ^d   Peat, Thomas S ^d   Thomas, Tim ^a,b   Baell, Jonathan B ^a,b,c   Parisot, John P ^a,b,c   Street, Ian P ^a,b,c  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c Cancer Therapeutics CRC P/L   (Australia)

^d CSIRO   (Australia)

Author keywords

acetyltransferase; high throughput screen; MOZ; small molecule

Indexed keywords

HISTONE ACETYLTRANSFERASE; HYBRID PROTEIN; PYRAZOLE DERIVATIVE; QUINAZOLINONE DERIVATIVE; ZINC FINGER PROTEIN;

ARTICLE; BIOSENSOR; ENZYME ACTIVITY; EPIGENETICS; HIGH THROUGHPUT SCREENING; MOLECULAR LIBRARY; MYELOID LEUKEMIA; PRIORITY JOURNAL; RADIOMETRY; SURFACE PLASMON RESONANCE;

ENZYME ACTIVATION; EPIGENESIS, GENETIC; HIGH-THROUGHPUT SCREENING ASSAYS; HISTONE ACETYLTRANSFERASES; HUMANS; REPRODUCIBILITY OF RESULTS; SMALL MOLECULE LIBRARIES;

EID: 83455178191     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111421631     Document Type: Article

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