Topiramate attenuates cerebral ischemia/reperfusion injury in gerbils via activating GABAergic signaling and inhibiting astrogliosis

Neurochemistry International

Volumn 60, Issue 1, 2012, Pages 39-46

  Mao, Xiaoyuan ^a   Ji, Changwei ^b   Sun, Chunyan ^b   Cao, Danfeng ^c   Ma, Ping ^b   Ji, Zhong ^b   Cao, Fangyuan ^b   Min, Dongyu ^a   Li, Shuzhi ^b   Cai, Jiqun ^a   Cao, Yonggang ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b Daqing Campus of Harbin Medical University ^*  (China)

^c PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

GABA receptor; GFAP; Global cerebral ischemia; KCC2; NKCC1; Topiramate

Indexed keywords

CASPASE 3; PROCASPASE 3; PROTEIN BAX; PROTEIN BCL 2; TOPIRAMATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRAIN ISCHEMIA; DRUG EFFECT; GABAERGIC SYSTEM; GERBIL; MALE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ASTROCYTES; BCL-2-ASSOCIATED X PROTEIN; BRAIN ISCHEMIA; CELL DEATH; FRUCTOSE; GERBILLINAE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; HIPPOCAMPUS; MALE; NEURONS; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, GABA-A; REPERFUSION INJURY;

GERBILLINAE;

EID: 83455177758     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.10.015     Document Type: Article

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