Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: Involvement of tenascin-C induced by aldosterone-mediated inflammation

Journal of Cardiovascular Pharmacology

Volumn 49, Issue 5, 2007, Pages 261-268

  Nishioka, Tomohiro ^a   Suzuki, Maiko ^a   Onishi, Katsuya ^a   Takakura, Nobuyuki ^b   Inada, Hiroyasu ^a   Yoshida, Toshimichi ^a   Hiroe, Michiaki ^c   Imanaka Yoshida, Kyoko ^a  

^a MIE UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

Aldosterone; Angiotensin II; Hypertension; Inflammation; Myocardial fibrosis; Tenascin

Indexed keywords

ALDOSTERONE; ANGIOTENSIN II; COLLAGEN TYPE 1; COLLAGEN TYPE 3; EPLERENONE; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; TENASCIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BLOOD PRESSURE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FIBROBLAST; HEART MUSCLE; HEART MUSCLE FIBROSIS; HYPERTENSION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IN VITRO STUDY; MACROPHAGE; MEDIATOR; MOUSE; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

ALDOSTERONE; ALDOSTERONE ANTAGONISTS; ANALYSIS OF VARIANCE; ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; BODY WEIGHT; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; FIBROBLASTS; FIBROSIS; HYPERTENSION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATION MEDIATORS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MACROPHAGES; MICE; MICE, INBRED BALB C; MYOCARDIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPIRONOLACTONE; TENASCIN; UP-REGULATION; VASOCONSTRICTOR AGENTS;

EID: 34249794560     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e318033dfd4     Document Type: Article

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