-
1
-
-
0023134446
-
Role in translation of a triple tandemly repeated sequence in the 5′-untranslated region of human thymidylate synthase mRNA
-
Kaneda S, Takeishi K, Ayusawa D, Shimizu K, Seno T, Altman S: Role in translation of a triple tandemly repeated sequence in the 5′-untranslated region of human thymidylate synthase mRNA. Nucleic Acids Res 1987;15:1259-1270.
-
(1987)
Nucleic Acids Res
, vol.15
, pp. 1259-1270
-
-
Kaneda, S.1
Takeishi, K.2
Ayusawa, D.3
Shimizu, K.4
Seno, T.5
Altman, S.6
-
2
-
-
0035671827
-
Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression
-
Kawakami K, Salonga D, Park JM, Danenberg KD, Uetake H, Brabender J, Omura K, Watanabe G, Danenberg PV: Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression. Clin Cancer Res 2001;7:4096-4101.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 4096-4101
-
-
Kawakami, K.1
Salonga, D.2
Park, J.M.3
Danenberg, K.D.4
Uetake, H.5
Brabender, J.6
Omura, K.7
Watanabe, G.8
Danenberg, P.V.9
-
3
-
-
0029122937
-
Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase
-
Horie N, Aiba H, Oguro K, Hojo H, Takeishi K: Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase. Cell Struct Funct 1995;20:191-197.
-
(1995)
Cell Struct Funct
, vol.20
, pp. 191-197
-
-
Horie, N.1
Aiba, H.2
Oguro, K.3
Hojo, H.4
Takeishi, K.5
-
4
-
-
0037096901
-
Prognostic value of tumoral thymidylate synthase and p53 in metastatic colorectal cancer patients receiving fluorouracil-based chemotherapy: Phenotypic and genotypic analyses
-
Etienne MC, Chazal M, Laurent-Puig P, Magne N, Rosty C, Formento JL, Francoual M, Formento P, Renee N, Chamorey E, Bourgeon A, Seitz JF, Delpero JR, Letoublon C, Pezet D, Milano G: Prognostic value of tumoral thymidylate synthase and p53 in metastatic colorectal cancer patients receiving fluorouracil-based chemotherapy: Phenotypic and genotypic analyses. J Clin Oncol 2002;20:2832-2843.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2832-2843
-
-
Etienne, M.C.1
Chazal, M.2
Laurent-Puig, P.3
Magne, N.4
Rosty, C.5
Formento, J.L.6
Francoual, M.7
Formento, P.8
Renee, N.9
Chamorey, E.10
Bourgeon, A.11
Seitz, J.F.12
Delpero, J.R.13
Letoublon, C.14
Pezet, D.15
Milano, G.16
-
5
-
-
14444285483
-
p53 mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: An analysis of response and survival
-
Lenz HJ, Hayashi K, Salonga D, Danenberg KD, Danenberg PV, Metzger R, Banerjee D, Bertino JR, Groshen S, Leichman LP, Leichman CG: p53 mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: An analysis of response and survival. Clin Cancer Res 1998;4:1243-1250.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1243-1250
-
-
Lenz, H.J.1
Hayashi, K.2
Salonga, D.3
Danenberg, K.D.4
Danenberg, P.V.5
Metzger, R.6
Banerjee, D.7
Bertino, J.R.8
Groshen, S.9
Leichman, L.P.10
Leichman, C.G.11
-
6
-
-
0028151449
-
The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
-
Johnston PG, Fisher ER, Rockette HE, Fisher B, Wolmark N, Drake JC, Chabner BA, Allegra CJ: The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 1994;12:2640-2647.
-
(1994)
J Clin Oncol
, vol.12
, pp. 2640-2647
-
-
Johnston, P.G.1
Fisher, E.R.2
Rockette, H.E.3
Fisher, B.4
Wolmark, N.5
Drake, J.C.6
Chabner, B.A.7
Allegra, C.J.8
-
7
-
-
0031941249
-
A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance
-
Yamachika T, Nakanishi H, Inada K, Tsukamoto T, Kato T, Fukushima M, Inoue M, Tatematsu M: A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance. Cancer 1998;82:70-77.
-
(1998)
Cancer
, vol.82
, pp. 70-77
-
-
Yamachika, T.1
Nakanishi, H.2
Inada, K.3
Tsukamoto, T.4
Kato, T.5
Fukushima, M.6
Inoue, M.7
Tatematsu, M.8
-
8
-
-
0033995850
-
Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method
-
Takenoue T, Nagawa H, Matsuda K, Fujii S, Nita ME, Hatano K, Kitayama J, Tsuruo T, Muto T: Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method. Ann Surg Oncol 2000;7:193-198.
-
(2000)
Ann Surg Oncol
, vol.7
, pp. 193-198
-
-
Takenoue, T.1
Nagawa, H.2
Matsuda, K.3
Fujii, S.4
Nita, M.E.5
Hatano, K.6
Kitayama, J.7
Tsuruo, T.8
Muto, T.9
-
9
-
-
0034087575
-
Thymidylate synthase expression: An independent prognostic factor for local recurrence, distant metastasis, disease-free and overall survival in rectal cancer
-
Edler D, Hallstrom M, Johnston PG, Magnusson I, Ragnhammar P, Blomgren H: Thymidylate synthase expression: An independent prognostic factor for local recurrence, distant metastasis, disease-free and overall survival in rectal cancer. Clin Cancer Res 2000;6:1378-1384.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1378-1384
-
-
Edler, D.1
Hallstrom, M.2
Johnston, P.G.3
Magnusson, I.4
Ragnhammar, P.5
Blomgren, H.6
-
10
-
-
0033981858
-
Immunohistochemically detected thymidylate synthase in colorectal cancer: An independent prognostic factor of survival
-
Edler D, Kressner U, Ragnhammar P, Johnston PG, Magnusson I, Glimelius B, Pahlman L, Lindmark G, Blomgren H: Immunohistochemically detected thymidylate synthase in colorectal cancer: An independent prognostic factor of survival. Clin Cancer Res 2000;6:488-492.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 488-492
-
-
Edler, D.1
Kressner, U.2
Ragnhammar, P.3
Johnston, P.G.4
Magnusson, I.5
Glimelius, B.6
Pahlman, L.7
Lindmark, G.8
Blomgren, H.9
-
11
-
-
0033050310
-
Increased thymidylate synthase gene expression in liver metastases from colorectal carcinoma: Implications for chemotherapeutic options and survival
-
Bathe OF, Franceschi D, Livingstone AS, Moffat FL, Tian E, Ardalan B: Increased thymidylate synthase gene expression in liver metastases from colorectal carcinoma: Implications for chemotherapeutic options and survival. Cancer J Sci Am 1999;5:34-40.
-
(1999)
Cancer J Sci Am
, vol.5
, pp. 34-40
-
-
Bathe, O.F.1
Franceschi, D.2
Livingstone, A.S.3
Moffat, F.L.4
Tian, E.5
Ardalan, B.6
-
12
-
-
0028800331
-
Colorectal cancer biology: Clinical implications
-
Johnston PG, Allegra CJ: Colorectal cancer biology: Clinical implications. Semin Oncol 1995;22:418-432.
-
(1995)
Semin Oncol
, vol.22
, pp. 418-432
-
-
Johnston, P.G.1
Allegra, C.J.2
-
13
-
-
0028242166
-
5-Fluorouracil and folinic acid in the treatment of advanced colorectal cancer: An updated meta-analysis
-
Brohee D: 5-Fluorouracil and folinic acid in the treatment of advanced colorectal cancer: An updated meta-analysis. Med Sci Res 1994;22:383-384.
-
(1994)
Med Sci Res
, vol.22
, pp. 383-384
-
-
Brohee, D.1
-
14
-
-
0345596364
-
Toxicity of fluorouracil in patients with advanced colorectal cancer: Effect of administration schedule and prognostic factors
-
Meta-Analysis Group In Cancer
-
Toxicity of fluorouracil in patients with advanced colorectal cancer: Effect of administration schedule and prognostic factors. Meta-Analysis Group In Cancer. J Clin Oncol 1998;16:3537-3541.
-
(1998)
J Clin Oncol
, vol.16
, pp. 3537-3541
-
-
-
15
-
-
13344269002
-
Relationship between 5-fluorouracil dose intensity and therapeutic response in patients with advanced colorectal cancer receiving infusional therapy containing 5-FU
-
Gamelin EC, Danquechin-Dorval EM, Dumesnil YF, Maillart PJ, Goudier MJ, Burtin PC, Delva RG, Lortholary AH, Gesta PH, Larra FG: Relationship between 5-fluorouracil dose intensity and therapeutic response in patients with advanced colorectal cancer receiving infusional therapy containing 5-FU. Cancer 1996;77:441-451.
-
(1996)
Cancer
, vol.77
, pp. 441-451
-
-
Gamelin, E.C.1
Danquechin-Dorval, E.M.2
Dumesnil, Y.F.3
Maillart, P.J.4
Goudier, M.J.5
Burtin, P.C.6
Delva, R.G.7
Lortholary, A.H.8
Gesta, P.H.9
Larra, F.G.10
-
16
-
-
0026079516
-
Pharmacokinetic and pharmacodynamic analysis of fluorouracil during 72-hour continuous infusion with and without dipyridamole
-
Trump DL, Egorin MJ, Forrest A, Willson JK, Remick S, Tutsch KD: Pharmacokinetic and pharmacodynamic analysis of fluorouracil during 72-hour continuous infusion with and without dipyridamole. J Clin Oncol 1991;9:2027-2035.
-
(1991)
J Clin Oncol
, vol.9
, pp. 2027-2035
-
-
Trump, D.L.1
Egorin, M.J.2
Forrest, A.3
Willson, J.K.4
Remick, S.5
Tutsch, K.D.6
-
17
-
-
0024512054
-
5-FU therapeutic monitoring with dose adjustment leads to an improved therapeutic index in head and neck cancer
-
Santini J, Milano G, Thyss A, Renee N, Viens P, Ayela P, Schneider M, Demard F: 5-FU therapeutic monitoring with dose adjustment leads to an improved therapeutic index in head and neck cancer. Br J Cancer 1989;59:287-290.
-
(1989)
Br J Cancer
, vol.59
, pp. 287-290
-
-
Santini, J.1
Milano, G.2
Thyss, A.3
Renee, N.4
Viens, P.5
Ayela, P.6
Schneider, M.7
Demard, F.8
-
18
-
-
0028006858
-
Population study of dihydropyrimidine dehydrogenase in cancer patients
-
Etienne MC, Lagrange JL, Dassonville O, Fleming R, Thyss A, Renee N, Schneider M, Demard F, Milano G: Population study of dihydropyrimidine dehydrogenase in cancer patients. J Clin Oncol 1994;12:2248-2253.
-
(1994)
J Clin Oncol
, vol.12
, pp. 2248-2253
-
-
Etienne, M.C.1
Lagrange, J.L.2
Dassonville, O.3
Fleming, R.4
Thyss, A.5
Renee, N.6
Schneider, M.7
Demard, F.8
Milano, G.9
-
19
-
-
0027426408
-
Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy
-
Lu Z, Zhang R, Diasio RB: Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy. Cancer Res 1993;53:5433-5438.
-
(1993)
Cancer Res
, vol.53
, pp. 5433-5438
-
-
Lu, Z.1
Zhang, R.2
Diasio, R.B.3
-
20
-
-
0023902287
-
Familial deficiency of dihydropyrimidine dehydrogenase: Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity
-
Diasio RB, Beavers TL, Carpenter JT: Familial deficiency of dihydropyrimidine dehydrogenase: Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity. J Clin Invest 1988;81:47-51.
-
(1988)
J Clin Invest
, vol.81
, pp. 47-51
-
-
Diasio, R.B.1
Beavers, T.L.2
Carpenter, J.T.3
-
21
-
-
0034808681
-
Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)-related toxicity compared with controls
-
Raida M, Schwabe W, Hausler P, Van Kuilenburg AB, Van Gennip AH, Behnke D, Hoffken K: Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)-related toxicity compared with controls. Clin Cancer Res 2001;7:2832-2839.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2832-2839
-
-
Raida, M.1
Schwabe, W.2
Hausler, P.3
Van Kuilenburg, A.B.4
Van Gennip, A.H.5
Behnke, D.6
Hoffken, K.7
-
22
-
-
0024347268
-
Biochemical modulation of fluorouracil: Evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma
-
Poon MA, O'Connell MJ, Moertel CG, Wieand HS, Cullinan SA, Everson LK, Krook JE, Mailliard JA, Laurie JA, Tschetter LK, et al: Biochemical modulation of fluorouracil: Evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma. J Clin Oncol 1989;7:1407-1418.
-
(1989)
J Clin Oncol
, vol.7
, pp. 1407-1418
-
-
Poon, M.A.1
O'Connell, M.J.2
Moertel, C.G.3
Wieand, H.S.4
Cullinan, S.A.5
Everson, L.K.6
Krook, J.E.7
Mailliard, J.A.8
Laurie, J.A.9
Tschetter, L.K.10
-
23
-
-
0003970808
-
Grading classification according to WHO
-
Morson BC, Dawson IM (eds): Oxford, Blackwell Scientific
-
Morson BC, Dawson IM, Day DW, et al: Grading classification according to WHO; in Morson BC, Dawson IM (eds): Morson and Dawson's Gastrointestinal Pathology, ed 3. Oxford, Blackwell Scientific, 1990, pp 67-77.
-
(1990)
Morson and Dawson's Gastrointestinal Pathology, Ed 3
, pp. 67-77
-
-
Morson, B.C.1
Dawson, I.M.2
Day, D.W.3
-
24
-
-
0031426423
-
Immunohistochemical determination of thymidylate synthase in colorectal cancer - Methodological studies
-
Edler D, Blomgren H, Allegra CJ, Johnston PG, Lagerstedt U, Magnusson I, Ragnhammar P: Immunohistochemical determination of thymidylate synthase in colorectal cancer - Methodological studies. Eur J Cancer 1997;33:2278-2281.
-
(1997)
Eur J Cancer
, vol.33
, pp. 2278-2281
-
-
Edler, D.1
Blomgren, H.2
Allegra, C.J.3
Johnston, P.G.4
Lagerstedt, U.5
Magnusson, I.6
Ragnhammar, P.7
-
25
-
-
0036188129
-
Predictive value of thymidylate synthase expression in resected metastases of colorectal cancer
-
Corsi DC, Ciaparrone M, Zannoni G, Mancini M, Cassano A, Specchia M, Pozzo C, Martini M, Barone C: Predictive value of thymidylate synthase expression in resected metastases of colorectal cancer. Eur J Cancer 2002;38:527-534.
-
(2002)
Eur J Cancer
, vol.38
, pp. 527-534
-
-
Corsi, D.C.1
Ciaparrone, M.2
Zannoni, G.3
Mancini, M.4
Cassano, A.5
Specchia, M.6
Pozzo, C.7
Martini, M.8
Barone, C.9
-
26
-
-
0029095796
-
Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial
-
Leichman L, Lenz HJ, Leichman CG, Groshen S, Danenberg K, Baranda J, Spears CP, Boswell W, Silberman H, Ortega A, et al: Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial. Eur J Cancer 1995;31:1306-1310.
-
(1995)
Eur J Cancer
, vol.31
, pp. 1306-1310
-
-
Leichman, L.1
Lenz, H.J.2
Leichman, C.G.3
Groshen, S.4
Danenberg, K.5
Baranda, J.6
Spears, C.P.7
Boswell, W.8
Silberman, H.9
Ortega, A.10
-
27
-
-
0032997572
-
Immunohistochemical quantitation of thymidylate synthase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy
-
Aschele C, Debernardis D, Casazza S, Antonelli G, Tunesi G, Baldo C, Lionetto R, Maley F, Sobrero A: Immunohistochemical quantitation of thymidylate synthase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy. J Clin Oncol 1999;17:1760-1770.
-
(1999)
J Clin Oncol
, vol.17
, pp. 1760-1770
-
-
Aschele, C.1
Debernardis, D.2
Casazza, S.3
Antonelli, G.4
Tunesi, G.5
Baldo, C.6
Lionetto, R.7
Maley, F.8
Sobrero, A.9
-
28
-
-
6544276581
-
Thymidylate synthase protein expression in advanced colon cancer: Correlation with the site of metastasis and the clinical response to leucovorinmodulated bolus 5-fluorouracil
-
Cascinu S, Aschele C, Barni S, Debernardis D, Baldo C, Tunesi G, Catalano V, Staccioli MP, Brenna A, Muretto P, Catalano G: Thymidylate synthase protein expression in advanced colon cancer: Correlation with the site of metastasis and the clinical response to leucovorinmodulated bolus 5-fluorouracil. Clin Cancer Res 1999;5:1996-1999.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1996-1999
-
-
Cascinu, S.1
Aschele, C.2
Barni, S.3
Debernardis, D.4
Baldo, C.5
Tunesi, G.6
Catalano, V.7
Staccioli, M.P.8
Brenna, A.9
Muretto, P.10
Catalano, G.11
-
29
-
-
0033009501
-
Colorectal liver metastasis thymidylate synthase staining correlates with response to hepatic arterial floxuridine
-
Davies MM, Johnston PG, Kaur S, Allen-Mersh TG: Colorectal liver metastasis thymidylate synthase staining correlates with response to hepatic arterial floxuridine. Clin Cancer Res 1999;5:325-328.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 325-328
-
-
Davies, M.M.1
Johnston, P.G.2
Kaur, S.3
Allen-Mersh, T.G.4
-
30
-
-
0030883708
-
Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protractedinfusion fluorouracil and weekly leucovorin
-
Leichman CG, Lenz HJ, Leichman L, Danenberg K, Baranda J, Groshen S, Boswell W, Metzger R, Tan M, Danenberg PV: Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protractedinfusion fluorouracil and weekly leucovorin. J Clin Oncol 1997;15:3223-3229.
-
(1997)
J Clin Oncol
, vol.15
, pp. 3223-3229
-
-
Leichman, C.G.1
Lenz, H.J.2
Leichman, L.3
Danenberg, K.4
Baranda, J.5
Groshen, S.6
Boswell, W.7
Metzger, R.8
Tan, M.9
Danenberg, P.V.10
-
31
-
-
0028940399
-
Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
-
Johnston PG, Lenz HJ, Leichman CG, Danenberg KD, Allegra CJ, Danenberg PV, Leichman L: Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 1995;55:1407-1412.
-
(1995)
Cancer Res
, vol.55
, pp. 1407-1412
-
-
Johnston, P.G.1
Lenz, H.J.2
Leichman, C.G.3
Danenberg, K.D.4
Allegra, C.J.5
Danenberg, P.V.6
Leichman, L.7
-
32
-
-
0036534108
-
Thymidylate synthase expression in colorectal cancer: A prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy
-
Edler D, Glimelius B, Hallstrom M, Jakobsen A, Johnston PG, Magnusson I, Ragnhammar P, Blomgren H: Thymidylate synthase expression in colorectal cancer: A prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy. J Clin Oncol 2002;20:1721-1728.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1721-1728
-
-
Edler, D.1
Glimelius, B.2
Hallstrom, M.3
Jakobsen, A.4
Johnston, P.G.5
Magnusson, I.6
Ragnhammar, P.7
Blomgren, H.8
-
33
-
-
0035576102
-
ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy
-
Shirota Y, Stoehlmacher J, Brabender J, Xiong YP, Uetake H, Danenberg KD, Groshen S, Tsao-Wei DD, Danenberg PV, Lenz HJ: ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy. J Clin Oncol 2001;19:4298-4304.
-
(2001)
J Clin Oncol
, vol.19
, pp. 4298-4304
-
-
Shirota, Y.1
Stoehlmacher, J.2
Brabender, J.3
Xiong, Y.P.4
Uetake, H.5
Danenberg, K.D.6
Groshen, S.7
Tsao-Wei, D.D.8
Danenberg, P.V.9
Lenz, H.J.10
-
34
-
-
0035868667
-
Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer
-
Villafranca E, Okruzhnov Y, Dominguez MA, Garcia-Foncillas J, Azinovic I, Martinez E, Illarramendi JJ, Arias F, Martinez Monge R, Salgado E, Angeletti S, Brugarolas A: Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer. J Clin Oncol 2001;19:1779-1786.
-
(2001)
J Clin Oncol
, vol.19
, pp. 1779-1786
-
-
Villafranca, E.1
Okruzhnov, Y.2
Dominguez, M.A.3
Garcia-Foncillas, J.4
Azinovic, I.5
Martinez, E.6
Illarramendi, J.J.7
Arias, F.8
Martinez Monge, R.9
Salgado, E.10
Angeletti, S.11
Brugarolas, A.12
-
35
-
-
0027426408
-
Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy
-
Lu Z, Zhang R, Diasio RB: Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy. Cancer Res 1993;53:5433-5438.
-
(1993)
Cancer Res
, vol.53
, pp. 5433-5438
-
-
Lu, Z.1
Zhang, R.2
Diasio, R.B.3
-
36
-
-
0023902287
-
Familial deficiency of dihydropyrimidine dehydrogenase: Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity
-
Diasio RB, Beavers TL, Carpenter JT: Familial deficiency of dihydropyrimidine dehydrogenase: Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity. J Clin Invest 1988;81:47-51.
-
(1988)
J Clin Invest
, vol.81
, pp. 47-51
-
-
Diasio, R.B.1
Beavers, T.L.2
Carpenter, J.T.3
-
37
-
-
0035750549
-
Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy
-
Pullarkat ST, Stoehlmacher J, Ghaderi V, Xiong YP, Ingles SA, Sherrod A, Warren R, Tsao-Wei D, Groshen S, Lenz HJ: Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy. Pharmacogenomics J 2001;1:65-70.
-
(2001)
Pharmacogenomics J
, vol.1
, pp. 65-70
-
-
Pullarkat, S.T.1
Stoehlmacher, J.2
Ghaderi, V.3
Xiong, Y.P.4
Ingles, S.A.5
Sherrod, A.6
Warren, R.7
Tsao-Wei, D.8
Groshen, S.9
Lenz, H.J.10
-
38
-
-
0034901306
-
Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: Frequency of the common IVS14 + 1G>A mutation causing DPD deficiency
-
van Kuilenburg AB, Muller EW, Haasjes J, Meinsma R, Zoetekouw L, Waterham HR, Baas F, Richel DJ, van Gennip AH: Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: Frequency of the common IVS14 + 1G>A mutation causing DPD deficiency. Clin Cancer Res 2001;7:1149-1153.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1149-1153
-
-
Van Kuilenburg, A.B.1
Muller, E.W.2
Haasjes, J.3
Meinsma, R.4
Zoetekouw, L.5
Waterham, H.R.6
Baas, F.7
Richel, D.J.8
Van Gennip, A.H.9
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