Progesterone receptor inhibits proliferation of human breast cancer cells via induction of MAPK phosphatase 1 (MKP-1/DUSP1)

Journal of Biological Chemistry

Volumn 286, Issue 50, 2011, Pages 43091-43102

  Chen, Chien Cheng ^a   Hardy, Daniel B ^a,b   Mendelson, Carole R ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b WESTERN UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-INFLAMMATORY ACTION; ANTI-PROLIFERATIVE; ANTIPROLIFERATIVE EFFECT; BREAST CANCER; BREAST CANCER CELLS; CELL TYPES; DEPHOSPHORYLATIONS; FETAL BOVINE SERUM; GLUCOCORTICOID RECEPTOR; HUMAN BREAST CANCER CELLS; LUCIFERASE REPORTER ASSAYS; MRNA LEVEL; PROGESTERONE RECEPTOR; PROMOTER ACTIVITIES; RESPONSE ELEMENTS; TRANSCRIPTION START SITE;

CELL CULTURE; CELL PROLIFERATION; DISEASES; PHOSPHATASES; PHOSPHORYLATION; TRANSCRIPTION;

CELLS;

GESTAGEN; GLUCOCORTICOID RECEPTOR; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PROGESTERONE; PROGESTERONE RECEPTOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP1;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CATALYSIS; CELL PROLIFERATION; CELL TYPE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INACTIVATION; ENZYME INDUCTION; ENZYME REPRESSION; ENZYME SPECIFICITY; GENE; GENE ACTIVITY; GENE CONTROL; GENE TARGETING; GENETIC TRANSCRIPTION; HORMONE BINDING; HUMAN; HUMAN CELL; MKP 1 GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION SITE; UPREGULATION;

BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; DUAL SPECIFICITY PHOSPHATASE 1; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOBLOTTING; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PROGESTERONE; PROMEGESTONE; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, PROGESTERONE; RNA INTERFERENCE;

EID: 83355169738     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.295865     Document Type: Article

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