Progesterone induces focal adhesion in breast cancer cells MDA-MB-231 transfected with progesterone receptor complementary DNA

Molecular Endocrinology

Volumn 14, Issue 3, 2000, Pages 348-358

  Lin, Valerie C L ^a   Ng, Eng Hen ^a   Aw, Swee Eng ^a   Tan, Michelle G K ^a   Ng, Esther H L ^a   Bay, Boon Huat ^b  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; ESTROGEN RECEPTOR ALPHA; FOCAL ADHESION KINASE; PAXILLIN; PROGESTERONE; PROGESTERONE RECEPTOR; TALIN;

ARTICLE; BREAST CANCER; CELL ADHESION; CELL CONTACT; CELL SPREADING; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 0034465068     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.14.3.0426     Document Type: Article

References (52)

1. Progestin regulation of cellular proliferation
2. Physiological action of progesterone in target tissues
3. Novel progesterone target genes identified by an improved differential display technique suggest that progestin-induced growth inhibition of breast cancer cells coincided with enhancement of differentiation
4. Hormones receptors: Their role in predicting prognosis and response to endocrine therapy
5. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities
6. Introduction of estrogen-responsiveness into mammalian cell lines
7. Preferential stimulation of human progesterone receptor B expression by estrogen in T47-D human breast cancer cells
8. Estrogenic sensitivity and its resistance in normal murine mammary glands
9. Activation of the silent progesterone receptor gene by ectopic expression of estrogen receptors in a rat fibroblast cell line
10. A one minute pulse of estradiol to MCF-7 breast cancer cells changes estrogen receptor binding properties and commits cells to induce estrogenic responses
11. Variant T47D human breast cancer cells with high progesterone receptor levels despite estrogen and antiestrogen resistance
12. The progesterone antagonist RU486 acquires agonist activity upon stimulation of cAMP signaling pathways
13. Biphasic regulation of breast cancer cell growth by progesterone: Role of the cyclin-dependent kinase inhibitors, p21 and p27Kip1
14. Expression of estrogen receptor-β in human breast tumors
15. Progestins inhibit the growth of MDA-MB-231 cells transfected with progesterone receptor complementary DNA
16. Integrin-mediated tyrosine phosphorylation of focal adhesion proteins and organization of the cytoskeleton
17. Paxillin, a new vinculin binding protein present in focal adhesions
18. Signal transduction through integrins: A central role for focal adhesion kinase?
19. Progestins and danazol effect on cell-to-cell adhesion, and E-cadherin and α- and β-catenin mRNA expressions
20. Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands
21. FAK, a structurally unique protein tyrosine kinase associated with focal adhesions
22. Integrin transmembrane signaling and cytoskeletal control
23. Signaling through focal adhesion kinase
24. Modulation of laminin receptor expression by estrogen and progestins in human breast cancer cell lines
25. Adhesion molecules: Novel molecular tools in tumor pathology
26. Beta-1 integrins mediated tumour cell adhesion to quiescent endothelial cells
27. Attachment characteristics and involvement of integrins in adhesion of breast cancer cell lines to extracellular bone matrix components
28. Hormonal regulation of acidic and basic fibroblast growth factor production and expression in mouse mammary gland
29. Progestin regulation of epidermal growth factor receptor in human mammary carcinoma cells
30. Regulation of transforming growth factor α and transforming growth factor β messenger ribonucleic acid abundance in T-47D human breast cancer cells
31. Expression of insulin-like growth factor binding proteins by T-47D human breast cancer cells: Regulation by progestins and antiestrogens
32. Effect of progesterone on serum levels of IGF-1 and on femur IGF-1 mRNA in ovariectomzed rats
33. Sex Steroid regulation of insulin-like growth factor system gene expression and proliferation in primate myometrium
34. Growth factor control of cultured uterine stromal cell proliferation is progesterone-dependent
35. Tyrosine phosphorylation of paxillin and focal adhesion kinase during insulin-like growth factor-1-stimulated lamellipodial advance
36. The roles of integrins and extracellular matrix proteins in the insulin-like growth factor 1-stimulated chemotaxis of human breast cancer cells
37. Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the α5β1 integrin by means of its Arg-Gly-Asp sequence
38. Interaction between the insulin-like growth factor family and the integrin receptor family in tissue repair processes - Evidence in a rabbit ear dermal ulcer model
39. Integration of integrin and growth factor receptor signaling pathways within the focal adhesion complex
40. Integrins, oncogenes, and anchorage independence
41. 125(FAK) focal adhesion kinase is a substrate for the insulin and insulin-like growth factor-1 tyrosine kinase receptors
42. Convergence of progesterone and epidermal growth factor signaling in breast cancer
43. Hypothesis: Progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals
44. Hormonal regulation of epidermal growth factor receptor content and signaling in bovine mammary tissue
45. In vitro regulation of human breast cancer cell adhesion and invasion via integrin receptors to the extracellular matrix
46. Integrin α2β1 can promote adhesion and spreading of metastatic breast carcinoma cells on the lymph node stroma
47. Common principles in cell adhesion
48. Collagen-induced rapid morphogenesis of human mammary epithelial cells: The role of the α2β1 integrin
49. Branching morphogenesis of human mammary epithelial cells in collagen gels
50. Integrin-matrix interactions affect the form of the structures developing from human mammary epithelial cells in collagen or fibrin gels
51. Transient expression of human H, chicken progesterone receptors does not support alternative translational initiation from a single mRNA as the mechanism generating two receptor isoforms
52. Subacute administration of zinc induces lipid droplet accumulation in the mouse liver