Nano rare-earth oxides induced size-dependent vacuolization: An independent pathway from autophagy

International Journal of Nanomedicine

Volumn 5, Issue 1, 2010, Pages 601-609

  Zhang, Ying ^a   Yu, Chenguang ^a   Huang, Guanyi ^a   Wang, Changli ^a   Wen, Longping ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Autophagy; Rare earth oxides; Size dependent; Vacuolization

Indexed keywords

3 METHYLADENINE; AUTOPHAGY PROTEIN 5; LANTHANUM; YTTERBIUM; YTTRIUM; ATG5 PROTEIN, MOUSE; GREEN FLUORESCENT PROTEIN; LANTHANIDE; LANTHANUM OXIDE; METAL NANOPARTICLE; MICROTUBULE ASSOCIATED PROTEIN; OXIDE; YTTRIA;

ARTICLE; AUTOPHAGY; BIOACCUMULATION; BIOLOGICAL ACTIVITY; CELL AGGREGATION; CELL VACUOLE; CENTRIFUGATION; CONTROLLED STUDY; HELA CELL; MOLECULAR MECHANICS; NANOANALYSIS; PARTICLE SIZE; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECT; FLUORESCENCE MICROSCOPY; GENE INACTIVATION; GENETICS; HUMAN; METABOLISM; MOUSE; NANOMEDICINE; PHYSIOLOGY; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ANIMALS; AUTOPHAGY; CELL LINE; GENE KNOCKOUT TECHNIQUES; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; LANTHANUM; METAL NANOPARTICLES; METALS, RARE EARTH; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; MICROTUBULE-ASSOCIATED PROTEINS; NANOMEDICINE; OXIDES; PARTICLE SIZE; VACUOLES; YTTERBIUM; YTTRIUM;

EID: 79952115823     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S11513     Document Type: Article

References (25)

1. Liu YN, Shi S, Mei WJ, et al. In vitro and in vivo investigations on the antiviral activity of a series of mixed-valence rare earth borotungstate heteropoly blues. Eur J Med Chem. 2008;43(9):1963-1970.
2. Liu J, Mei W, Li Y, Wang E, Ji L, Tao P. Antiviral activity of mixedvalence rare earth borotungstate heteropoly blues against influenza virus in mice. Antivir Chem Chemother. 2000;11(6):367-372.
3. Patil S, Sandberg A, Heckert E, Self W, Seal S. Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential. Biomaterials. 2007;28(31):4600-4607.
4. Chen J, Patil S, Seal S, McGinnis JF. Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides. Nat Nanotechnol. 2006;1(2):142-150.
5. Heckert EG, Karakoti AS, Seal S, Self W. The role of cerium redox state in the SOD mimetic activity of nanoceria. Biomaterials. 2008;29(18): 2705-2709.
6. Chen J, Patil S, Seal S, McGinnis JF. Nanoceria particles prevent ROIinduced blindness. Adv Exp Med Biol. 2008;613:53-59.
7. Park EJ, Choi J, Park YK, Park K. Oxidative stress induced by cerium oxide nanoparticles in cultured BEAS-2B cells. Toxicology. 2008; 245(1-2):90-100.
8. Wang X, Yuan L, Huang J, Zhang TL, Wang K. Lanthanum enhances in vitro osteoblast differentiation via pertussis toxin-sensitive gi protein and ERK signaling pathway. J Cell Biochem. 2008;105(5): 1307-1315.
9. Schubert D, Dargusch R, Raitano J, Chan SW. Cerium and yttrium oxide nanoparticles are neuroprotective. Biochem Biophys Res Commun. 2006;342(1):86-91.
10. Das M, Patil S, Bhargava N, et al. Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons. Biomaterials. 2007;28(10):1918-1925.
11. Yu L, Lu Y, Na M, Yu SH, Wen LP. Rare earth oxide nanocrystals induce autophagy in HeLa cells. Small. 2009;5(24):2784-2787.
12. Belkin M, Hardy WG, Orr HC, Lachman AB. Induction in vitro by autonomic drugs of cytoplasmic vacuoles in ascites tumor cells. J Natl Cancer Inst. 1962;28:187-201.
13. Henics T, Wheatley DN. Cytoplasmic vacuolation, adaptation and cell death: a view on new perspectives and features. Biol Cell. 1999;91: 485-498.
14. Seleverstov O, Zabirnyk O, Zscharnack M, et al. Quantum dots for human mesenchymal stem cells labeling. A size-dependent autophagy activation. Nano Lett. 2006;6:2826-2832.
15. Pan Y, Neuss S, Leifert A, et al. Size-dependent cytotoxicity of gold nanoparticles. Small. 2007;3(11)1941-1949.
16. Chen X, Wang Z. Regulation of intracellular trafficking of the EGF receptor by Rab5 in the absence of phosphatidylinositol 3-kinase activity. EMBO Rep. 2001;2:68-74.
17. Houle S, Marceau F. Wortmannin alters the intracellular trafficking of the bradykinin B2 receptor: role of phosphoinositide 3-kinase and Rab5. Biochem J. 2003;375:151-158.
18. Blommaart EF, Krause U, Schellens JP, Vreeling-Sindelárová H, Meijer AJ. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY 294002 inhibit autophagy in isolated rat hepatocytes. Eur J Biochem. 1997;243(1-2)240-246.
19. Chen Y, Yang L, Feng C, et al. Nano neodymium oxide induces massive vacuolization and autophagic cell death in non-small cell lung cancer NCI-H460 cells. Biochem Biophys Res Commun. 2005;337:52-60.
20. Zhang Q, Yang W, Man N, et al. Autophagy-mediated chemosensitization in cancer cells by fullerene C60 nanocrystal. Autophagy. 2009;19:5(8).
21. Sayesa CM, Gobinb AM, et al. Colvina. Biomaterials. 2005;26: 7587-7595.
22. Yamawaki H, Iwai N. Cytotoxicity of water-soluble fullerene in vascular endothelial cells. Am J Physiol Cell Physiol. 2006;290:C1495-C1502.
23. Chun E, Lee KY. Bcl-2 and Bcl-XL are important for the induction paclitaxel resistance in human hepatocellular carcinoma cells. Biochem Biophys Res Commun. 2004;315:771-779.
24. Klee M, Pimentel-Muinos FX. Bcl-XL specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum. J Cell Biol. 2005;168:723-734.
25. Tong-sheng C, Xiao-ping W, Lei S, Long-xiang W, Da X, Martin M. Taxol induces caspase-independent cytoplasmic vacuolization and cell death through endoplasmic reticulum (ER) swelling in ASTC-a-1 cells. Cancer Lett. 2008;270:164-172.