Protein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1)

Journal of Biological Chemistry

Volumn 286, Issue 50, 2011, Pages 43559-43568

  O'Neill, Audrey K ^a   Gallegos, Lisa L ^a,e   Justilien, Verline ^b   Garcia, Erin L ^c   Leitges, Michael ^d   Fields, Alan P ^b   Hall, Randy A ^c   Newton, Alexandra C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MAYO CLINIC   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF OSLO   (Norway)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MIGRATION; CELLULAR MIGRATION; CLASS I; CO-IMMUNOPRECIPITATION EXPERIMENTS; FUNCTIONAL ASSAYS; INVASIVENESS; NON SMALL CELL LUNG CANCER; PDZ BINDING MOTIF; PDZ DOMAINS; PHOSPHORYLATION SITES; PROTEIN KINASE C; PROTEOMIC ARRAYS; SIGNALING PATHWAYS; SPATIAL SEGREGATION; WOUND HEALING;

CELLS; CYTOLOGY; ISOENZYMES; LIGANDS; PHOSPHORYLATION; PROTEINS;

SCAFFOLDS (BIOLOGY);

DISC LARGE HOMOLOG 1; DISHEVELLED PROTEIN; PDZ PROTEIN; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN ZO1; SCAFFOLD PROTEIN; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CARBOXY TERMINAL SEQUENCE; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LUNG NON SMALL CELL CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; PROTEOMICS; WOUND HEALING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ASTROCYTES; BINDING SITES; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; CELLS, CULTURED; HUMANS; IMMUNOPRECIPITATION; MEMBRANE PROTEINS; MICE; PDZ DOMAINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASE C-ALPHA; RNA, SMALL INTERFERING;

EID: 83355163339     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.294603     Document Type: Article

References (57)

1. Pawson, C. T., and Scott, J. D. (2010) Nat. Struct. Mol. Biol. 17, 653-658
2. Rosse, C., Linch, M., Kermorgant, S., Cameron, A. J., Boeckeler, K., and Parker, P. J. (2010) Nat. Rev. Mol. Cell Biol. 11, 103-112
3. Newton, A. C. (2010) Am. J. Physiol. Endocrinol. Metab. 298, E395-E402
4. Dempsey, E. C., Newton, A. C., Mochly-Rosen, D., Fields, A. P., Reyland, M. E., Insel, P. A., and Messing, R. O. (2000) Am. J. Physiol. Lung Cell Mol. Physiol. 279, L429-L438
5. Castagna, M., Takai, Y., Kaibuchi, K., Sano, K., Kikkawa, U., and Nishizuka, Y. (1982) J. Biol. Chem. 257, 7847-7851
6. Konopatskaya, O., and Poole, A. W. (2010) Trends Pharmacol Sci. 31, 8-14
7. Fan, Q. W., Cheng, C., Knight, Z. A., Haas-Kogan, D., Stokoe, D., James, C. D., McCormick, F., Shokat, K. M., and Weiss, W. A. (2009) Sci. Signal. 2, ra4
8. Guo, J., Ibaragi, S., Zhu, T., Luo, L. Y., Hu, G. F., Huppi, P. S., and Chen, C. Y. (2008) Cancer Res. 68, 8473-8481
9. Holinstat, M., Mehta, D., Kozasa, T., Minshall, R. D., and Malik, A. B. (2003) J. Biol. Chem. 278, 28793-28798
10. Larsson, C. (2006) Cell. Signal. 18, 276-284
11. Dean, N., McKay, R., Miraglia, L., Howard, R., Cooper, S., Giddings, J., Nicklin, P., Meister, L., Ziel, R., Geiger, T., Muller, M., and Fabbro, D. (1996) Cancer Res. 56, 3499-3507
12. Paz-Ares, L., Douillard, J. Y., Koralewski, P., Manegold, C., Smit, E. F., Reyes, J. M., Chang, G. C., John, W. J., Peterson, P. M., Obasaju, C. K., Lahn, M., and Gandara, D. R. (2006) J. Clin. Oncol. 24, 1428-1434
13. Fields, A. P., and Murray, N. R. (2008) Adv. Enzyme Regul. 48, 166-178
14. Mochly-Rosen, D., Khaner, H., and Lopez, J. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 3997-4000
15. Mochly-Rosen, D., and Gordon, A. S. (1998) FASEB J. 12, 35-42
16. Poole, A. W., Pula, G., Hers, I., Crosby, D., and Jones, M. L. (2004) Trends Pharmacol. Sci. 25, 528-535
17. Tsunoda, S., Sierralta, J., Sun, Y., Bodner, R., Suzuki, E., Becker, A., Socolich, M., and Zuker, C. S. (1997) Nature 388, 243-249
18. Adamski, F. M., Zhu, M. Y., Bahiraei, F., and Shieh, B. H. (1998) J. Biol. Chem. 273, 17713-17719
19. van Ham, M., and Hendriks, W. (2003) Mol. Biol. Rep. 30, 69-82
20. Lee, H. J., and Zheng, J. J. (2010) Cell Commun. Signal. 8, 8
21. Staudinger, J., Lu, J., and Olson, E. N. (1997) J. Biol. Chem. 272, 32019-32024
22. Leitges, M., Kovac, J., Plomann, M., and Linden, D. J. (2004) Neuron 44, 585-594
23. Lim, I. A., Hall, D. D., and Hell, J. W. (2002) J. Biol. Chem. 277, 21697-21711
24. Colledge, M., Dean, R. A., Scott, G. K., Langeberg, L. K., Huganir, R. L., and Scott, J. D. (2000) Neuron 27, 107-119
25. Kunkel, M. T., Garcia, E. L., Kajimoto, T., Hall, R. A., and Newton, A. C. (2009) J. Biol. Chem. 284, 24653-24661
26. Lau, A. G., and Hall, R. A. (2001) Biochemistry 40, 8572-8580
27. Citro, S., Malik, S., Oestreich, E. A., Radeff-Huang, J., Kelley, G. G., Smrcka, A. V., and Brown, J. H. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 15543-15548
28. Valster, A., Tran, N. L., Nakada, M., Berens, M. E., Chan, A. Y., and Symons, M. (2005) Methods 37, 208-215
29. Deleted in proof
30. Roberts, S., Calautti, E., Vanderweil, S., Nguyen, H. O., Foley, A., Baden, H. P., and Viel, A. (2007) Exp. Cell Res. 313, 2521-2530
31. Hsu, Y. C., Yuan, S., Chen, H. Y., Yu, S. L., Liu, C. H., Hsu, P. Y., Wu, G., Lin, C. H., Chang, G. C., Li, K. C., and Yang, P. C. (2009) Clin. Cancer Res. 15, 7309-7315
32. Park, E. S., Rabinovsky, R., Carey, M., Hennessy, B. T., Agarwal, R., Liu, W., Ju, Z., Deng, W., Lu, Y., Woo, H. G., Kim, S. B., Cheong, J. H., Garraway, L. A., Weinstein, J. N., Mills, G. B., Lee, J. S., and Davies, M. A. (2010) Mol. Cancer Ther. 9, 257-267
33. Abeyweera, T. P., Chen, X., and Rotenberg, S. A. (2009) J. Biol. Chem. 284, 17648-17656
34. Anilkumar, N., Parsons, M., Monk, R., Ng, T., and Adams, J. C. (2003) EMBO J. 22, 5390-5402
35. Bass, M. D., Roach, K. A., Morgan, M. R., Mostafavi-Pour, Z., Schoen, T., Muramatsu, T., Mayer, U., Ballestrem, C., Spatz, J. P., and Humphries, M. J. (2007) J. Cell Biol. 177, 527-538
36. Elfenbein, A., Rhodes, J. M., Meller, J., Schwartz, M. A., Matsuda, M., and Simons, M. (2009) J. Cell Biol. 186, 75-83
37. Horowitz, A., Tkachenko, E., and Simons, M. (2002) J. Cell Biol. 157, 715-725
38. Kim, J., Thorne, S. H., Sun, L., Huang, B., and Mochly-Rosen, D. (2011) Oncogene 30, 323-333
39. Kohutek, Z. A., diPierro, C. G., Redpath, G. T., and Hussaini, I. M. (2009) J. Neurosci. 29, 4605-4615
40. Lin, C. W., Shen, S. C., Chien, C. C., Yang, L. Y., Shia, L. T., and Chen, Y. C. (2010) J. Cell. Physiol. 225, 472-481
41. Arora, S., Ranade, A. R., Tran, N. L., Nasser, S., Sridhar, S., Korn, R. L., Ross, J. T., Dhruv, H., Foss, K. M., Sibenaller, Z., Ryken, T., Gotway, M. B., Kim, S., and Weiss, G. J. (2011) Int. J. Cancer 129, 2621-2631
42. Bilder, D. (2004) Genes Dev. 18, 1909-1925
43. Humbert, P. O., Grzeschik, N. A., Brumby, A. M., Galea, R., Elsum, I., and Richardson, H. E. (2008) Oncogene 27, 6888-6907
44. Cavatorta, A. L., Fumero, G., Chouhy, D., Aguirre, R., Nocito, A. L., Giri, A. A., Banks, L., and Gardiol, D. (2004) Int. J. Cancer 111, 373-380
45. Unno, K., Hanada, T., and Chishti, A. H. (2008) Exp. Cell Res. 314, 3118-3129
46. Caruana, G., and Bernstein, A. (2001) Mol. Cell. Biol. 21, 1475-1483
47. Etienne-Manneville, S., Manneville, J. B., Nicholls, S., Ferenczi, M. A., and Hall, A. (2005) J. Cell Biol. 170, 895-901
48. Manneville, J. B., Jehanno, M., and Etienne-Manneville, S. (2010) J. Cell Biol. 191, 585-598
49. Dujardin, D. L., and Vallee, R. B. (2002) Curr. Opin. Cell Biol. 14, 44-49
50. Hough, C. D., Woods, D. F., Park, S., and Bryant, P. J. (1997) Genes Dev. 11, 3242-3253
51. Newman, R. A., and Prehoda, K. E. (2009) J. Biol. Chem. 284, 12924-12932
52. Funke, L., Dakoji, S., and Bredt, D. S. (2005) Annu. Rev. Biochem. 74, 219-245
53. Marcello, E., Gardoni, F., Mauceri, D., Romorini, S., Jeromin, A., Epis, R., Borroni, B., Cattabeni, F., Sala, C., Padovani, A., and Di Luca, M. (2007) J. Neurosci. 27, 1682-1691
54. Lue, R. A., Marfatia, S. M., Branton, D., and Chishti, A. H. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 9818-9822
55. Parra, M., Gascard, P., Walensky, L. D., Gimm, J. A., Blackshaw, S., Chan, N., Takakuwa, Y., Berger, T., Lee, G., Chasis, J. A., Snyder, S. H., Mohandas, N., and Conboy, J. G. (2000) J. Biol. Chem. 275, 3247-3255
56. Diakowski, W., Grzybek, M., and Sikorski, A. F. (2006) Folia Histochem Cytobiol. 44, 231-248
57. Manno, S., Takakuwa, Y., and Mohandas, N. (2005) J. Biol. Chem. 280, 7581-7587