The role of 123I-FP-CIT-SPECT in the differential diagnosis of Parkinson and tremor syndromes: A critical assessment of 125 cases

Journal of Neurology

Volumn 258, Issue 12, 2011, Pages 2147-2154

  Sixel Döring, Friederike ^a   Liepe, Knut ^b   Mollenhauer, Brit ^a   Trautmann, Ellen ^a   Trenkwalder, Claudia ^a  

^a PARACELSUS ELENA KLINIK   (Germany)

^b KLINIKUM KASSEL   (Germany)

Author keywords

DAT SPECT; Diagnosis; Parkinson's disease; SWEDDs; Tremor

Indexed keywords

DOPAMINE; FLUOROPROPYL CARBOMETHOXY IODOPHENYL TROPAN I 123; IODINE 123; LEVODOPA; RADIOACTIVE IODINE; RADIOLIGAND; UNCLASSIFIED DRUG; 2 CARBOMETHOXY 8 (3 FLUOROPROPYL) 3 (4 IODOPHENYL)TROPANE; 2-CARBOMETHOXY-8-(3-FLUOROPROPYL)-3-(4-IODOPHENYL)TROPANE; DIAGNOSTIC AGENT; DOPAMINE TRANSPORTER; RADIOPHARMACEUTICAL AGENT; TROPANE DERIVATIVE;

ADULT; AGED; ARTICLE; CLINICAL ASSESSMENT; CLINICAL FEATURE; CORPUS STRIATUM; DIFFERENTIAL DIAGNOSIS; DRUG RESPONSE; DYSTONIA; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; PARKINSON DISEASE; PRIORITY JOURNAL; REMISSION; RETROSPECTIVE STUDY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TREMOR; BRAIN; ESSENTIAL TREMOR; METABOLISM; METHODOLOGY; MIDDLE AGED; PARKINSONISM; SCINTISCANNING;

AGED; BRAIN; DIAGNOSIS, DIFFERENTIAL; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; ESSENTIAL TREMOR; FEMALE; HUMANS; IODINE RADIOISOTOPES; MALE; MIDDLE AGED; PARKINSONIAN DISORDERS; RADIOPHARMACEUTICALS; RETROSPECTIVE STUDIES; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TROPANES;

EID: 83255192154     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-011-6076-z     Document Type: Article

References (40)

1. J Booij TG Hemelaar JD Speelman K de Bruin AG Janssen EA van Royen 1999 One-day protocol for imaging of the nigrostriatal dopaminergic pathway in Parkinson's disease by [123I]FPCIT SPECT J Nucl Med 40 753 761 10319746 1:CAS:528:DyaK1MXjsVamur8%3D (Pubitemid 29210748)
2. A Antonini R Benti R De Notaris, et al. 2003 123I-Ioflupane/SPECT binding to striatal dopamine transporter (DAT) uptake in patients with Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy Neurol Sci 24 149 150 14598060 10.1007/s10072-003-0103-5 1:STN:280:DC%2BD3srhvF2qsg%3D%3D (Pubitemid 37304286)
3. TS Benamer J Patterson DG Grosset, et al. 2000 Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123I]-FP-CIT SPECT imaging: the [123I]-FP-CIT study group Mov Disord 15 503 510 10830416 10.1002/1531-8257(200005)15:3<503::AID-MDS1013>3.0.CO;2-V 1:STN:280:DC%2BD3cvnsVSntw%3D%3D (Pubitemid 30333223)
4. AM Catafau E Tolosa 2004 Impact of dopamine transporter SPECT using 123I-Ioflupane on diagnosis and management of patients with clinically uncertain parkinsonian syndromes Mov Disord 19 1175 1182 15390019 10.1002/mds.20112 (Pubitemid 39433368)
5. V Marshall DG Grosset 2003 Role of dopamine transporter imaging in the diagnosis of atypical tremor disorders Mov Disord 18 Suppl 7 S22 S27 14531042 10.1002/mds.10574 (Pubitemid 37336924)
6. M Plotkin H Amthauer S Klaffke, et al. 2005 Combined 123I-FP-CIT and 123I-IBZM SPECT for the diagnosis of parkinsonian syndromes: study on 72 patients J Neural Transm 112 677 692 15375677 10.1007/s00702-004-0208-x 1:STN:280:DC%2BD2M7ps1SnsA%3D%3D (Pubitemid 40591200)
7. L Filippi C Manni M Pierantozzi, et al. 2005 123I-FP-CIT semi-quantitative SPECT detects preclinical bilateral dopaminergic deficit in early Parkinson's disease with unilateral symptoms Nucl Med Commun 26 421 426 15838424 10.1097/00006231-200505000-00005 1:CAS:528:DC%2BD2MXjtlKks70%3D (Pubitemid 40617730)
8. J Booij G Tissingh GJ Boer, et al. 1997 [123I]FP-CIT SPECT shows a pronounced decline of striatal dopamine transporter labelling in early and advanced Parkinson's disease J Neurol Neurosurg Psychiatry 62 133 140 9048712 10.1136/jnnp.62.2.133 1:STN:280:DyaK2s3gtVyrsQ%3D%3D
9. J Booij JD Speelman MW Horstink EC Wolters 2001 The clinical benefit of imaging striatal dopamine transporters with [123I]FP-CIT SPET in differentiating patients with presynaptic parkinsonism from those with other forms of parkinsonism Eur J Nucl Med 28 266 272 11315592 10.1007/s002590000460 1:CAS:528:DC%2BD3MXitFeiur0%3D
10. DL Jennings JP Seibyl D Oakes S Eberly J Murphy K Marek 2004 (123I) Beta-CIT and single-photon emission computed tomographic imaging vs clinical evaluation in parkinsonian syndrome: unmasking an early diagnosis Arch Neurol 61 1224 1229 15313838 10.1001/archneur.61.8.1224 (Pubitemid 39062674)
11. F Doepp M Plotkin L Siegel, et al. 2008 Brain parenchyma sonography and 123I-FP-CIT SPECT in Parkinson's disease and essential tremor Mov Disord 23 405 410 18067184 10.1002/mds.21861
12. SA Schneider MJ Edwards P Mir, et al. 2007 Patients with adult-onset dystonic tremor resembling parkinsonian tremor have scans without evidence of dopaminergic deficit (SWEDDs) Mov Disord 22 2210 2215 17712858 10.1002/mds.21685
13. J Shahed J Jankovic 2007 Exploring the relationship between essential tremor and Parkinson's disease Parkinsonism Relat Disord 13 67 76 16887374 10.1016/j.parkreldis.2006.05.033 (Pubitemid 46329516)
14. MD Yahr D Orosz DP Purohit 2003 Co-occurrence of essential tremor and Parkinson's disease: clinical study of a large kindred with autopsy findings Parkinsonism Relat Disord 9 225 231 12618058 10.1016/S1353-8020(02)00057-3 1:STN:280:DC%2BD3s7gs1Sqtw%3D%3D (Pubitemid 36287155)
15. ED Louis G Levy H Mejia-Santana, et al. 2003 Risk of action tremor in relatives of tremor-dominant and postural instability gait disorder PD Neurology 61 931 936 14557562 1:STN:280:DC%2BD2c%2FitFOluw%3D%3D (Pubitemid 37248647)
16. WG Ondo D Lai 2005 Olfaction testing in patients with tremor-dominant Parkinson's disease: is this a distinct condition? Mov Disord 20 471 475 15597336 10.1002/mds.20365 (Pubitemid 40779022)
17. R Pahwa WC Koller 1993 Is there a relationship between Parkinson's disease and essential tremor? Clin Neuropharmacol 16 30 35 8422655 10.1097/00002826-199302000-00003 1:STN:280:DyaK3s7jslagtA%3D%3D (Pubitemid 23028495)
18. JJ Geraghty J Jankovic WJ Zetusky 1985 Association between essential tremor and Parkinson's disease Ann Neurol 17 329 333 4004153 10.1002/ana.410170404 1:STN:280:DyaL2M3itl2itw%3D%3D (Pubitemid 15079057)
19. KR Chaudhuri M Buxton-Thomas V Dhawan R Peng C Meilak DJ Brooks 2005 Long duration asymmetrical postural tremor is likely to predict development of Parkinson's disease and not essential tremor: clinical follow-up study of 13 cases J Neurol Neurosurg Psychiatry 76 115 117 15608009 10.1136/jnnp.2004.046292 (Pubitemid 40013503)
20. ED Louis LS Honig JP Vonsattel DM Maraganore S Borden CB Moskowitz 2005 Essential tremor associated with focal nonnigral Lewy bodies: a clinicopathologic study Arch Neurol 62 1004 1007 15956174 10.1001/archneur.62.6. 1004 (Pubitemid 40973465)
21. K Marek D Jennings J Seibyl 2005 Long-term follow-up of patients with scans without evidence of dopaminergic deficit (SWEDD) in the ELLDOPA study Neurology 64 A274 (Abstract)
22. K Marek J Seibyl Parkinson's Study Group 2003 β-CIT scans without evidence of dopaminergic deficit (SWEDD) in the ELLDOPA-CIT and CALM-CIT study: long-term imaging assessment Neurology 60 A298 (Abstract)
23. P Schwingenschuh D Ruge MJ Edwards, et al. 2010 Distinguishing SWEDDs patients with asymmetric resting tremor from Parkinson's disease: a clinical and electrophysiological study Mov Disord 25 560 569 20131394 10.1002/mds.23019
24. G Deuschl P Bain M Brin 1998 Consensus statement of the Movement Disorder Society on Tremor. Ad Hoc Scientific Committee Mov Disord 13 Suppl 3 2 23 9827589 (Pubitemid 28517753)
25. WR Gibb AJ Lees 1988 The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease J Neurol Neurosurg Psychiatry 51 745 752 2841426 10.1136/jnnp.51.6.745 1:STN:280:DyaL1czgtVSqsg%3D%3D
26. Fahn S, Elton R, Members of the UPDRS Development Committee (1987) Unified Parkinson's disease rating scale. In: Fahn S, Marsden D, Caine D, Goldstein M (eds) Recent developments in Parkinson's disease. Macmillan Healthcare Information, Florham Park, p 375
27. L Chang 1978 A method for attenuation correction in computed tomography IEEE Trans Nucl Sci 25 638 643 10.1109/TNS.1978.4329385
28. S Asenbaum W Pirker P Angelberger G Bencsits M Pruckmayer T Brucke 1998 [123I]Beta-CIT and SPECT in essential tremor and Parkinson's disease J Neural Transm 105 1213 1228 9928890 10.1007/s007020050124 1:CAS:528:DyaK1MXhslGms7g%3D (Pubitemid 29017402)
29. WS Huang SZ Lin JC Lin SP Wey G Ting RS Liu 2001 Evaluation of early stage Parkinson's disease with 99mTc-TRODAT-1 imaging J Nucl Med 42 1303 1308 11535717 1:STN:280:DC%2BD3MvptlelsQ%3D%3D (Pubitemid 32852603)
30. C Scherfler J Schwarz A Antonini, et al. 2007 Role of DAT-SPECT in the diagnostic work up of parkinsonism Mov Disord 22 1229 1238 17486648 10.1002/mds.21505 (Pubitemid 47325028)
31. G Kagi KP Bhatia E Tolosa 2010 The role of DAT-SPECT in movement disorders J Neurol Neurosurg Psychiatry 81 5 12 20019219 10.1136/jnnp.2008. 157370 1:STN:280:DC%2BD1MfjtFygtw%3D%3D
32. G Deuschl R Elble 2009 Essential tremor-neurodegenerative or nondegenerative disease towards a working definition of ET Mov Disord 24 2033 2041 19750493 10.1002/mds.22755
33. PD Mozley HJ Kim RC Gur, et al. 1996 Iodine-123-IPT SPECT imaging of CNS dopamine transporters: nonlinear effects of normal aging on striatal uptake values J Nucl Med 37 1965 1970 8970515 1:CAS:528:DyaK2sXmtVGrtg%3D%3D (Pubitemid 26428363)
34. PK Morrish JS Rakshi DL Bailey GV Sawle DJ Brooks 1998 Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F]dopa PET J Neurol Neurosurg Psychiatry 64 314 319 9527140 10.1136/jnnp.64.3.314 1:STN:280:DyaK1c7os1eksg%3D%3D
35. NL Khan E Graham P Critchley, et al. 2003 Parkin disease: a phenotypic study of a large case series Brain 126 1279 1292 12764051 10.1093/brain/awg142 (Pubitemid 36644375)
36. RE Barrett MD Yahr RC Duvoisin 1970 Torsion dystonia and spasmodic torticollis-results of treatment with l-dopa Neurology 20 107 113 5529472 1:STN:280:DyaE3M%2FjtVyjug%3D%3D
37. M Coleman 1970 Preliminary remarks on the l-dopa therapy of dystonia Neurology 20 114 121 5529473 1:STN:280:DyaE3M%2FjtVyjuw%3D%3D
38. DJ Hensman PG Bain 2006 Levodopa can worsen tremor associated with dystonia Mov Disord 21 1778 1780 16856131 10.1002/mds.21043 (Pubitemid 44742221)
39. VL Marshall J Patterson DM Hadley KA Grosset DG Grosset 2006 Two-year follow-up in 150 consecutive cases with normal dopamine transporter imaging Nucl Med Commun 27 933 937 17088677 10.1097/01.mnm.0000243374.11260.5b (Pubitemid 44706887)
40. R Hilker C Klein K Hedrich, et al. 2002 The striatal dopaminergic deficit is dependent on the number of mutant alleles in a family with mutations in the parkin gene: evidence for enzymatic parkin function in humans Neurosci Lett 323 50 54 11911988 10.1016/S0304-3940(01)02529-0 1:CAS:528:DC%2BD38XitFaqurY%3D (Pubitemid 34241617)