13C-methacetin breath test reproducibility study reveals persistent CYP1A2 stimulation on repeat examinations

World Journal of Gastroenterology

Volumn 17, Issue 45, 2011, Pages 4979-4986

  Kasicka Jonderko, Anna ^a   Nita, Anna ^a   Jonderko, Krzysztof ^a   Kamińska, Magdalena ^a   Błońska Fajfrowska, Barbara ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Breath test; Isotope application in medicine; Liver; Reproducibility

Indexed keywords

4 ACETANISIDINE; CARBON 13; CYTOCHROME P450 1A2; ACETAMIDE DERIVATIVE; CARBON;

13C METHACETIN BREATH TEST; ADULT; ARTICLE; BREATH ANALYSIS; CARBON DIOXIDE BREATHING; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; LUNG FUNCTION TEST; MALE; NORMAL HUMAN; REPRODUCIBILITY; AREA UNDER THE CURVE; METABOLISM; METHODOLOGY; SENSITIVITY AND SPECIFICITY;

ACETAMIDES; ADULT; AREA UNDER CURVE; BREATH TESTS; CARBON ISOTOPES; CYTOCHROME P-450 CYP1A2; FEMALE; HUMANS; MALE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 83155177114     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v17.i45.4979     Document Type: Article

References (42)

1. Ilan Y. Review article: the assessment of liver function using breath tests. Aliment Pharmacol Ther 2007; 26: 1293-1302
2. Braden B, Lembcke B, Kuker W, Caspary WF. 13C-breath tests: current state of the art and future directions. Dig Liver Dis 2007; 39: 795-805
3. Modak AS. Stable istotope breath tests in clinical medicine: a review. J Breath Res 2007; 1: R1-R13
4. Armuzzi A, Candelli M, Zocco MA, Andreoli A, De Lorenzo A, Nista EC, Miele L, Cremonini F, Cazzato IA, Grieco A, Gasbarrini G, Gasbarrini A. Review article: breath testing for human liver function assessment. Aliment Pharmacol Ther 2002; 16: 1977-1996
5. Braden B, Faust D, Sarrazin U, Zeuzem S, Dietrich CF, Caspary WF, Sarrazin C. 13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection. Aliment Pharmacol Ther 2005; 21: 179-185
6. Lalazar G, Pappo O, Hershcovici T, Hadjaj T, Shubi M, Ohana H, Hemed N, Ilan Y. A continuous 13C methacetin breath test for noninvasive assessment of intrahepatic inflammation and fibrosis in patients with chronic HCV infection and normal ALT. J Viral Hepat 2008; 15: 716-728
7. Holtmeier J, Leuschner M, Schneider A, Leuschner U, Caspary WF, Braden B. 13C-methacetin and 13C-galactose breath tests can assess restricted liver function even in early stages of primary biliary cirrhosis. Scand J Gastroenterol 2006; 41: 1336-1341
8. Schneider A, Caspary WF, Saich R, Dietrich CF, Sarrazin C, Kuker W, Braden B. 13C-methacetin breath test shortened: 2-point-measurements after 15 minutes reliably indicate the presence of liver cirrhosis. J Clin Gastroenterol 2007; 41: 33-37
9. Portincasa P, Grattagliano I, Lauterburg BH, Palmieri VO, Palasciano G, Stellaard F. Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis. Clin Sci (Lond) 2006; 111: 135-143
10. Matsumoto K, Suehiro M, Iio M, Kawabe T, Shiratori Y, Okano K, Sugimoto T. [13C]methacetin breath test for evaluation of liver damage. Dig Dis Sci 1987; 32: 344-348
11. Klatt S, Taut C, Mayer D, Adler G, Beckh K. Evaluation of the 13C-methacetin breath test for quantitative liver function testing. Z Gastroenterol 1997; 35: 609-614
12. Pfaffenbach B, Götze O, Szymanski C, Hagemann D, Adamek RJ. [The 13C-methacetin breath test for quantitative noninvasive liver function analysis with an isotope-specific nondispersive infrared spectrometer in liver cirrhosis]. Dtsch Med Wochenschr 1998; 123: 1467-1471
13. Zipprich A, Meiss F, Steudel N, Sziegoleit U, Fleig WE, Kleber G. 13C-Methacetin metabolism in patients with cirrhosis: relation to disease severity, haemoglobin content and oxygen supply. Aliment Pharmacol Ther 2003; 17: 1559-1562
14. Festi D, Capodicasa S, Sandri L, Colaiocco-Ferrante L, Staniscia T, Vitacolonna E, Vestito A, Simoni P, Mazzella G, Portincasa P, Roda E, Colecchia A. Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels. World J Gastroenterol 2005; 11: 142-148
15. Petrolati A, Festi D, De Berardinis G, Colaiocco-Ferrante L, Di Paolo D, Tisone G, Angelico M. 13C-methacetin breath test for monitoring hepatic function in cirrhotic patients before and after liver transplantation. Aliment Pharmacol Ther 2003; 18: 785-790
16. The representatives of 61 States. Preamble to the Constitution of the World Health Organization. Proceeding of the International Health Conference; 1946 Jun 19-Jul 22. New York: Official Records of the World Health Organization, 1946: 100
17. Jonderko K, Kasicka-Jonderko A, Syrkiewicz-Trepiak D, Błońska-Fajfrowska B. Feasibility of a breath test with a substrate of natural 13C-abundance and isotope-selective non-dispersive infrared spectrometry: a preliminary study. J Gastroenterol Hepatol 2005; 20: 1228-1234
18. Kasicka-Jonderko A, Jonderko K, Kamińska M, Szymszal M, Długajczyk M, Bula M, Bielecka M, Błońska-Fajfrowska B. Breath 13CO2 profiles after intake of three naturally abundant in 13C foods rich in carbohydrates. Ann Acad Med Siles 2006; 60: 206-212. Available from: URL: http://journals.indexcopernicus.com/abstracted.php?icid=676292
19. Jonderko K, Kasicka-Jonderko A, Kamińska M, Błońska-Fajfrowska B. A systematic study of a neutral meal suitable for subjects undergoing 13CO2 breath tests. Med Sci Monit 2008; 14: CR543-CR546
20. 2 recovery in breath air after per oral administration of [13C] methacetin in two groups of different ages. Isotopes Environ Health Stud 2008; 44: 295-303
21. Jonderko K, Duś Z, Szymszal M, Kasicka-Jonderko A, Błońska-Fajfrowska B. Normative values for the 13C-mixed triglyceride breath test in two age groups. Med Sci Monit 2009; 15: CR255-CR259
22. Jonderko K, Spinková M, Kamińska M, Kasicka-Jonderko A, Błońska-Fajfrowska B. Ability to digest starch assessed noninvasively with a 13CO2 breath test - comparison of results obtained in two groups of different age. Med Sci Monit 2009; 15: CR128-CR133
23. Kasicka-Jonderko A, Loska D, Jonderko K, Kaminska M, Błonska-Fajfrowska B. Interference of acute cigarette smoking with [13C]methacetin breath test. Isotopes Environ Health Stud 2011; 47: 34-41
24. Kasicka-Jonderko A, Jonderko K, Kamińska M, Bielecka M, Błońska-Fajfrowska B. 13C-alpha-Ketoisocaproic acid breath test revisited: an in-depth reproducibility study advocates an extended breath sampling period. Dig Dis Sci 2007; 52: 3481-3487
25. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 1: 307-310
26. Brennan P, Silman A. Statistical methods for assessing observer variability in clinical measures. BMJ 1992; 304: 1491-1494
27. Loo FD, Palmer DW, Soergel KH, Kalbfleisch JH, Wood CM. Gastric emptying in patients with diabetes mellitus. Gastroenterology 1984; 86: 485-494
28. Jonderko K. Short- and long-term reproducibility of radioisotopic examination of gastric emptying. Int J Rad Appl Instrum B 1990; 17: 297-301
29. Armitage P. Statistical methods in medical research. Oxford: Blackwell Scientific Publications, 1978
30. StatSoft. Electronic statistics textbook. Tulsa: StatSoft, 2007. Available from: URL: http://www.statsoft.com/textbook/stathome.html
31. Jonderko K, Gabriel-Jaśniok A, Szymszal M, Kasicka-Jonderko A, Błońska-Fajfrowska B. Unreliability of breath methane as a candidate indicator of functional bowel disorders. Gut Liver 2008; 2: 180-185
32. Krusiec-Swidergoł B, Jonderko K. Multichannel electrogastrography under a magnifying glass--an in-depth study on reproducibility of fed state electrogastrograms. Neurogastroenterol Motil 2008; 20: 625-634
33. Jonderko K, Kasicka-Jonderko A, Krusiec-Swidergoł B, Dzielicki M, Strój L, Doliński M, Doliński K, Błońska-Fajfrowska B. How reproducible is cutaneous electrogastrography? An in-depth evidence-based study. Neurogastroenterol Motil 2005; 17: 800-809
34. Kasicka-Jonderko A, Szymszal M, Jonderko K, Piekarska A, Błońska-Fajfrowska B. Reproducibility of liquid gastric emptying measurement with the use of an ultra low dose of 13C-Sodium acetate and isotope-selective nondispersive infrared spectrometry. Ann Acad Med Siles 2005; 59: 144-152. Available from: URL: http://tombe.viamedica.pl/aams/pdf/2.pdf
35. Kasicka-Jonderko A, Kamińska M, Jonderko K, Setera O, Błońska-Fajfrowska B. Short- and medium-term reproducibility of gastric emptying of a solid meal determined by a low dose of 13C-octanoic acid and nondispersive isotope-selective infrared spectrometry. World J Gastroenterol 2006; 12: 1243-1248
36. Ilan Y. A fourth dimension in decision making in hepatology. Hepatol Res 2010; 40: 1143-1154
37. Liu YX, Huang LY, Wu CR, Cui J. Measurement of liver function for patients with cirrhosis by 13C-methacetin breath test compared with Child-Pugh score and routine liver function tests. Chin Med J (Engl) 2006; 119: 1563-1566
38. Lalazar G, Adar T, Ilan Y. Point-of-care continuous (13)C-methacetin breath test improves decision making in acute liver disease: results of a pilot clinical trial. World J Gastroenterol 2009; 15: 966-972
39. Krumbiegel P, Günther K, Faust H, Möbius G, Hirschberg K, Schneider G. Nuclear medicine liver function tests for pregnant women and children. 1. Breath tests with 14C-methacetin and 13C-methacetin. Eur J Nucl Med 1985; 10: 129-133
40. Wutzke KD, Forberger A, Wigger M. Effect of alcohol consumption on the liver detoxication capacity as measured by [13C]methacetin- and [methyl-13C]methionine-breath tests. Isotopes Environ Health Stud 2008; 44: 219-226
41. Ciccocioppo R, Candelli M, Di Francesco D, Ciocca F, Taglieri G, Armuzzi A, Gasbarrini G, Gasbarrini A. Study of liver function in healthy elderly subjects using the 13C-methacetin breath test. Aliment Pharmacol Ther 2003; 17: 271-277
42. Iikura Y, Iwasaki A, Tsubaki T, Akasawa A, Onda T, Katsunuma T, Miura K, Ebisawa M, Saito H, Koya N. Study of liver function in infants with atopic dermatitis using the 13C-methacetin breath test. Int Arch Allergy Immunol 1995; 107: 189-193