Review article: The assessment of liver function using breath tests

Alimentary Pharmacology and Therapeutics

Volumn 26, Issue 10, 2007, Pages 1293-1302

  Ilan, Y ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

4 ACETANISIDINE; 4 ACETANISIDINE C 13; OCTANOIC ACID C 13; PARACETAMOL; RADIOPHARMACEUTICAL AGENT; STEROID; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANTIVIRAL THERAPY; AREA UNDER THE CURVE; AUTOIMMUNE HEPATITIS; BREATH ANALYSIS; CHOLESTATIC HEPATITIS; CHRONIC LIVER DISEASE; DIAGNOSTIC PROCEDURE; DRUG MEGADOSE; DRUG OVERDOSE; FOLLOW UP; HUMAN; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER FUNCTION; LIVER RESECTION; LIVER TRANSPLANTATION; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; REVIEW; SCORING SYSTEM; SCREENING; SENSITIVITY AND SPECIFICITY;

ACETAMIDES; BREATH TESTS; FEMALE; HUMANS; LIVER DISEASES; LIVER FUNCTION TESTS; MALE; TREATMENT OUTCOME;

EID: 35748968463     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2007.03519.x     Document Type: Review

References (47)

1. Crockett SD, Kaltenbach T, Keeffe EB. Do we still need a liver biopsy? Are the serum fibrosis tests ready for prime time? Clin Liver Dis 2006 10 : 513 34. viii.
2. Hepner GW, Vesell ES. Assessment of aminopyrine metabolism in man by breath analysis after oral administration of 14C-aminopyrine Effects of phenobarbital, disulfiram and portal cirrhosis. N Engl J Med 1974 291 : 1384 8.
3. Hsieh CB, Yu CY, Tzao C, et al. Prediction of the risk of hepatic failure in patients with portal vein invasion hepatoma after hepatic resection. Eur J Surg Oncol 2006 32 : 72 6.
4. Stehr A, Ploner F, Traeger K, et al. Plasma disappearance of indocyanine green: a marker for excretory liver function? Intensive Care Med 2005 31 : 1719 22.
5. 13C] phenylalanine breath test with air isotope ratio mass spectrometry can reflect the activity of phenylalanine hydroxylase in cirrhotic rat liver. Rapid Commun Mass Spectrom 2006 20 : 602 8.
6. 13C- phenylalanine breath test to evaluate functional capacity of hepatocyte in patients with liver cirrhosis and acute hepatitis. Aliment Pharmacol Ther 2005 21 : 851 9.
7. 13C-breath tests in hepatology (cytosolic liver function). Eur Rev Med Pharmacol Sci 2004 8 : 47 9.
8. 13C]Methionine breath test: a novel method to detect antiretroviral drug-related mitochondrial toxicity. J Antimicrob Chemother 2005 55 : 84 9.
9. Park GJ, Katelaris PH, Jones DB, et al. The C-caffeine breath test distinguishes significant fibrosis in chronic hepatitis B and reflects response to lamivudine therapy. Aliment Pharmacol Ther 2005 22 : 395 403.
10. Utecht KN, Hiles JJ, Kolesar J. Effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors. Am J Health Syst Pharm 2006 63 : 2340 8.
11. Liu L, Pang KS. An integrated approach to model hepatic drug clearance. Eur J Pharm Sci 2006 29 : 215 30.
12. Barstow L, Small RE. Liver function assessment by drug metabolism. Pharmacotherapy 1990 10 : 280 8.
13. 13C-methacetin breath test for quantitative liver function testing. Z Gastroenterol 1997 35 : 609 14.
14. 13C-methacetin breath test: isotope-selective nondispersive infrared spectrometry in comparison to isotope ratio mass spectrometry in volunteers and patients with liver cirrhosis. Z Gastroenterol 1999 37 : 1139 43.
15. 13C]methacetin breath test for evaluation of liver damage. Dig Dis Sci 1987 32 : 344 8.
16. 13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection. Aliment Pharmacol Ther 2005 21 : 179 85.
17. 13C-methacetin breath test accurately detects liver fibrosis in patients with chronic HCV infection or non-alcoholic fatty liver disease. J Hepatol 2007 46 : S209.
18. 13C-urea breath test device for the diagnosis of Helicobacter pylori infection: continuous online measurements allow for faster test results with high accuracy. J Clin Gastroenterol 2003 37 : 139 41.
19. Lysy J, Israeli E, Strauss-Liviatan N, Goldin E. Relationships between hypoglycaemia and gastric emptying abnormalities in insulin-treated diabetic patients. Neurogastroenterol Motil 2006 18 : 433 40.
20. Cholongitas E, Papatheodoridis GV, Vangeli M, Terreni N, Patch D, Burroughs AK. Systematic review: the model for end-stage liver disease - should it replace Child-Pugh's classification for assessing prognosis in cirrhosis? Aliment Pharmacol Ther 2005 22 : 1079 89.
21. Cholongitas E, Senzolo M, Patch D, Shaw S, Hui C, Burroughs AK. Review article: scoring systems for assessing prognosis in critically ill adult cirrhotics. Aliment Pharmacol Ther 2006 24 : 453 64.
22. Cholongitas E, Marelli L, Shusang V, et al. A systematic review of the performance of the model for end-stage liver disease (MELD) in the setting of liver transplantation. Liver Transpl 2006 12 : 1049 61.
23. 13C-Methaceting breath test (MBT) for follow-up of patients with acute liver disease. J Hepatol 2006 44 : S63.
24. 13C-methacetin breath test shortened: 2-point-measurements after 15 minutes reliably indicate the presence of liver cirrhosis. J Clin Gastroenterol 2007 41 : 33 7.
25. 13C-methacetin breath test compared with Child-Pugh score and routine liver function tests. Chin Med J 2006 119 : 1563 6.
26. Shiffman ML, Luketic VA, Sanyal AJ, et al. Hepatic lidocaine metabolism and liver histology in patients with chronic hepatitis and cirrhosis. Hepatology 1994 19 : 933 40.
27. 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels. World J Gastroenterol 2005 11 : 142 8.
28. Clark JM. The epidemiology of nonalcoholic fatty liver disease in adults. J Clin Gastroenterol 2006 40 : S5 10.
29. Portincasa P, Grattagliano I, Lauterburg BH, Palmieri VO, Palasciano G, Stellaard F. Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis. Clin Sci 2006 111 : 135 43.
30. ® test system in patients with NAFLD. Hepatology 2006 44 : 653A.
31. Furrer K, Deoliveira ML, Graf R, Clavien PA. Improving outcome in patients undergoing liver surgery. Liver Int 2007 27 : 26 39.
32. Sugimoto H, Okochi O, Hirota M, et al. Early detection of liver failure after hepatectomy by indocyanine green elimination rate measured by pulse dye-densitometry. J Hepatobiliary Pancreat Surg 2006 13 : 543 8.
33. Chung H, Kudo M, Haji S, et al. A proposal of the modified liver damage classification for hepatocellular carcinoma. Hepatol Res 2006 34 : 124 9.
34. Sakka SG, van Hout N. Relation between indocyanine green (ICG) plasma disappearance rate and ICG blood clearance in critically ill patients. J Intensive Care Med 2006 32 : 766 9.
35. Ohwada S, Kawate S, Hamada K, et al. Perioperative real-time monitoring of indocyanine green clearance by pulse spectrophotometry predicts remnant liver functional reserve in resection of hepatocellular carcinoma. Br J Surg 2006 93 : 339 46.
36. Schneider PD. Preoperative assessment of liver function. Surg Clin North Am 2004 84 : 355 73.
37. 13C-Methacetin breath test in evaluating hepatic injury in rats. Gastroenterology 2007 132 : A827.
38. Botero RC, Lucey MR. Organ allocation: model for end-stage liver disease, Child-Turcotte-Pugh, Mayo risk score, or something else. Clin Liver Dis 2003 7 : 715 27.
39. Huo TI, Lin HC, Lee SD. Model for end-stage liver disease and organ allocation in liver transplantation: where are we and where should we go? J Chin Med Assoc 2006 69 : 193 8.
40. Kim WR, Dickson ER. Timing of liver transplantation. Semin Liver Dis 2000 20 : 451 64.
41. 13C-methacetin breath test for monitoring hepatic function in cirrhotic patients before and after liver transplantation. Aliment Pharmacol Ther 2003 18 : 785 90.
42. Hay JE. Liver transplantation for primary biliary cirrhosis and primary sclerosing cholangitis: does medical treatment alter timing and selection? Liver Transpl Surg 1998 4 : S9 17.
43. 13C-galactose breath tests can assess restricted liver function even in early stages of primary biliary cirrhosis. Scand J Gastroenterol 2006 41 : 1336 41.
44. Kanematsu M, Kondo H, Goshima S, et al. Imaging liver metastases: review and update. Eur J Radiol 2006 58 : 217 28.
45. 13C-Methacetin breath testing accurately identifies significant liver inflammation and fibrosis: a novel method for assessing liver damage. Gastroenterology 2007 132 : A739.
46. 13C-methacetin breath test. Aliment Pharmacol Ther 2003 17 : 271 7.
47. 13C-Methacetin metabolism in patients with cirrhosis: relation to disease severity, haemoglobin content and oxygen supply. Aliment Pharmacol Ther 2003 17 : 1559 62.