BK channels in cardiovascular disease: A complex story of channel dysregulation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 297, Issue 5, 2009, Pages

  Rusch, Nancy J ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL;

ARTERY CONSTRICTION; BIOCHEMISTRY; CARDIOVASCULAR DISEASE; CELL MEMBRANE; DEPOLARIZATION; EDITORIAL; HUMAN; MEMBRANE POTENTIAL; METABOLIC SYNDROME X; NONHUMAN; PRIORITY JOURNAL; RESISTANCE BLOOD VESSEL; SARCOPLASMIC RETICULUM; SMOOTH MUSCLE FIBER; VASOCONSTRICTION; VASODILATATION;

ANIMALS; ARTERIOLES; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CARDIOVASCULAR DISEASES; CORONARY CIRCULATION; CORONARY VESSELS; HUMANS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL BETA SUBUNITS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MEMBRANE POTENTIALS; METABOLIC SYNDROME X; MICROCIRCULATION; MUSCLE, SMOOTH, VASCULAR; PHENOTYPE; VASOCONSTRICTION; VASODILATION;

EID: 70350455540     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00852.2009     Document Type: Editorial

References (41)

1. + channels as a new mechanism of agonist-induced vasoconstriction. Proc Natl Acad Sci USA 99: 14560-14565, 2002.
2. 1 subunit in genetic hypertension. Circ Res 93: 965-971, 2003.
3. + current in rat saphenous artery. Hypertension 19: 725-729, 1992.
4. Ca channels in metabolic syndrome. Am J Physiol Heart Circ Physiol (September 11, 2009). doi:10.1152/ajpheart.00466.2009.
5. Brayden JE, Nelson MT. Regulation of arterial tone by activation of calcium-dependent potassium channels. Science 256: 532-535, 1992.
6. + channels and dilation in small, resistance-size arteries. Mol Pharmacol 72: 359-369, 2007.
7. Butler A, Tsunoda S, McCobb DP, Wei A, Salkoff L. mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. Science 261: 221-224, 1993.
8. 1 subunit in vascular tissues from spontaneously hypertensive rats. Am J Hypertens 19: 678-685, 2006.
9. Dong L, Zheng YM, Riper DV, Rathore R, Liu QH, Singer HA, Wang YX. Functional and molecular evidence for impairment of calcium-activated potassium channels in type-1 diabetic cerebral artery smooth muscle cells. J Cereb Blood Flow Metab 28: 377-386, 2008. (Pubitemid 351161293)
10. + current in arterial membranes from genetically hypertensive rats. Am J Physiol Heart Circ Physiol 264: H1337-H1345, 1993.
11. Friedman SM, Friedman CL. Cell permeability, sodium transport, and the hypertensive process in the rat. Circ Res 39: 433-441, 1976.
12. Jones AW. Altered ion transport in vascular smooth muscle from spontaneously hypertensive rats. Circ Res 33: 563-572, 1973.
13. Jones AW. Reactivity of ion fluxes in rat aorta during hypertension and circulatory control. Fed Proc 33: 133-137, 1974.
14. Jones AW, Hart RG. Altered ion transport in aortic smooth muscle during deoxycorticosterone acetate hypertension in the rat. Circ Res 37: 333-341, 1975.
15. Knaus HG, Garcia-Calvo M, Kaczorowski GJ, Garcia ML. Subunit composition of the high conductance calcium-activated potassium channel from smooth muscle, a representative of the mSlo and slowpoke family of potassium channels. J Biol Chem 269: 3921-3924, 1994. (Pubitemid 24237733)
16. + channel from smooth muscle. J Biol Chem 269: 17274-17278, 1994.
17. + channel. J Biol Chem 270: 22434-22439, 1995.
18. Knudsen JD, Dincer UD, Bratz IN, Sturek M, Dick GM, Tune JD. Mechanisms of coronary dysfunction in obesity and insulin resistance. Microcirculation 14: 317-338, 2007. (Pubitemid 47050025)
19. Ledoux J, Werner ME, Brayden JE, Nelson MT. Calcium-activated potassium channels and the regulation of vascular tone. Physiology 21: 69-78, 2006.
20. Liu Y, Jones AW, Sturek M. Increased barium influx and potassium current in stroke-prone spontaneously hypertensive rats. Hypertension 23: 1091-1095, 1994. (Pubitemid 24180873)
21. + current in arterial smooth muscle cells from aldosterone-salt hypertensive rats. Am J Physiol Heart Circ Physiol 269: H1246-H1257, 1995.
22. + channels in the cerebral microcirculation of genetically hypertensive rats: evidence for their protection against cerebral vasospasm. Circ Res 82: 729-737, 1998.
23. + channels in the coronary artery smooth muscle cells of Zucker diabetic fatty rats. Biophys J 95: 5165-5177, 2008.
24. + channels in coronary smooth muscle during aging. Circ Res 88: 210-216, 2001.
25. McCobb DP, Fowler NL, Featherstone T, Lingle CJ, Saito M, Krause JE, Salkoff L. A human calcium-activated potassium channel gene expressed in vascular smooth muscle. Am J Physiol Heart Circ Physiol 269: H767-H777, 1995.
26. 2+-activated potassium β1 channel subunit in retinal arteriolar smooth muscle. Circ Res 100: 703-711, 2007.
27. + channels in diabetic dyslipidemic pigs is prevented by exercise. J Appl Physiol 95: 1179-1193, 2003.
28. Mokelke EA, Dietz NJ, Eckman DM, Nelson MT, Sturek M. Diabetic dyslipidemia and exercise affect coronary tone and differential regulation of conduit and microvessel K+ current. Am J Physiol Heart Circ Physiol 288: H1233-H1241, 2005. (Pubitemid 40270029)
29. Nelson MT, Cheng H, Rubart M, Santana LF, Bonev AD, Knot HJ, Lederer WJ. Relaxation of arterial smooth muscle by calcium sparks. Science 270: 633-637, 1995.
30. + channels in arterial smooth muscle and contributes to hypertension. J Biol Chem 282: 3231-3240, 2007.
31. Nishimaru K, Eghbali M, Lu R, Marijic J, Stefani E, Toro L. Functional and molecular evidence of MaxiK channel β1 subunit decrease with coronary artery aging in the rat. J Physiol 559: 849-862, 2004. (Pubitemid 39276173)
32. + current is enhanced in arterial membranes of hypertensive rats. Hypertension 19: 301-307, 1992.
33. Rusch NJ, Runnells AM. Remission of high blood pressure reverses arterial potassium channel alterations. Hypertension 23: 941-945, 1994.
34. Ca channel activity from pig coronary artery. Am J Physiol Cell Physiol 262: C708-C713, 1992.
35. Smith JM, Jones AW. Calcium antagonists inhibit elevated potassium efflux from aorta of aldosterone-salt hypertensive rats. Hypertension 15: 78-83, 1991.
36. Ca channels in human coronary smooth muscle: predominant α + β subunit complexes. J Physiol 502: 545-557, 1997.
37. Thompson LP, Bruner CA, Lamb FS, King CM, Webb RC. Calcium influx and vascular reactivity in systemic hypertension. Am J Cardiol 59: 29A-34A, 1987.
38. Toro L, Amador M, Stefani E. ANG II inhibits calcium-activated potassium channels from coronary smooth muscle in lipid bilayers. Am J Physiol Heart Circ Physiol 258: H912-H915, 1990. (Pubitemid 20103229)
39. Valverde MA, Rojas P, Amigo J, Cosmelli D, Orio P, Bahamonde MI, Mann GE, Vergara C, Latorre R. Acute activation of maxi-K channels (hSlo) by estradiol binding to the β subunit. Science 285: 1929-1931, 1999.
40. Xu H, Jackson WJ, Fink GD, Galligan JJ. Activation of potassium channels by tempol in arterial smooth muscle cells from normotensive and deoxycorticosterone acetate-salt hypertensive rats. Hypertension 48: 1080-1087, 2006. (Pubitemid 44772711)
41. Yang Y, Jones AW, Thomas TR, Rubin LJ. Influence of sex, high-fat diet, and exercise training on potassium currents of swine coronary smooth muscle. Am J Physiol Heart Circ Physiol 293: H1553-H1563, 2007. (Pubitemid 47367200)