Granulocyte colony stimulating factor neuroprotective effects on spinal motoneurons after ventral root avulsion

Synapse

Volumn 66, Issue 2, 2012, Pages 128-141

  De freria, Camila Marques ^a   Barbizan, Roberta ^a   De Oliveira, Alexandre Leite Rodrigues ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

G CSF; Glial cells; Spinal motoneuron; Synaptic plasticity; Ventral root avulsion

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; GRANULOCYTE COLONY STIMULATING FACTOR; NERVE PROTEIN; PROTEIN IBA 1; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; AVULSION INJURY; CELL SURVIVAL; FEMALE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MICROGLIA; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD INJURY; SPINAL CORD MOTONEURON; SYNAPSE; TRANSMISSION ELECTRON MICROSCOPY; VENTRAL ROOT AVULSION;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; DISEASE MODELS, ANIMAL; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; MOTOR NEURONS; NEUROPROTECTIVE AGENTS; PRESYNAPTIC TERMINALS; PRIMARY CELL CULTURE; RATS; RATS, INBRED LEW; RHIZOTOMY; SPINAL CORD; SPINAL NERVE ROOTS;

EID: 83055184244     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20993     Document Type: Article

References (39)

1. Abercrombie M, Johnson ML. 1946. Quantitative histology of Wallerian degeneration. I. Nuclear population in rabbit sciatic nerve. J Anat 80: 37-50.
2. Aharoni R, Kayhan B, Eilam R, Sela M, Arnon R. 2003. Gatiramer acetatespecific T cells in the brain express T helper 2/3 cytokines and brain-derived neurotrophic factor in situ. Proc Natl Acad Sci USA 100: 14157-14162.
3. Barbizan R, Oliveira ALR. 2010. Impact of acute inflammation on spinal motoneuron synaptic plasticity following ventral root avulsion. J Neuroinflam 7: 29-45.
4. Carlstedt T. 2009. Nerve root replantation. Neurosurg Clin N Am 20: 39-50.
5. Conradi S. 1969. On motoneuron synaptology in adult cats. Acta Physiol Scand 332: 1-57.
6. Deng Y, Xu Z, Xu B, Tian Y, Xin X, Deng X, Gao J. 2009. The protective effect of riluzole on manganese caused disruption of glutamate-glutamine cycle in rats. Brain Res 1289: 106-117.
7. Demetri GD, Griffin JD. 1991. Granulocyte colony-stimulating factor and its receptor. Blood 78: 2791-2808.
8. Eggers R, Tannemaat MR, Ehlert EM, Verhaagen J. 2010. A spatio-temporal analysis of motoneuron survival, axonal regeneration and neurotrophic factor expression after lumbar ventral root avulsion and implantation. Exp Neurol 223: 207-220.
9. Emirandetti A, Zanon RG, Sabha JR, Oliveira ALR. 2006. Astrocyte reactivity influences the number of presynaptic terminals apposed to spinal motoneurons after axotomy. Brain Res 1095: 35-42.
10. Hammarberg H, Lidman O, Lundberg C, Eltayeb SY, Gielen AW, Muhallab S, Svenningsson A, Lindå H, van Der Meide PH, Cullheim S, Olsson T, Piehl F. 2000. Neuroprotection by encephalomyelitis: Rescue of mechanically injured neurons and neurotrophin production by CNS-infiltrating T and natural killer cells. J Neurosci 20: 5283-5291.
11. Hoang TX, Akhavan M, Wu J, Havton LA. 2008. Minocycline protects motor but not autonomic neurons after cauda equina injury. 189: 71-77.
12. Jahn K, Schleinger F, Jin LJ, Dengler R, Buffer J, Krampfl K. 2008. Molecular mechanisms of interaction between the neuroprotective substance riluzole and GABA(A)-receptors. Naunyn Schmiedebergs Arch Pharmacol 378: 53-63.
13. Koda M, Nishio Y, Kamada T, Someya Y, Okawa A, Mori C, Yoshinaga K, Okada S, Moriya H, Yamazaki M. 2007. Granulocyte colony-stimulating factor (G-CSF) mobilizes bone marrow-derived cells into injured spinal cord and promotes functional recovery after compression-induced spinal cord injury in mice. Brain Res 1149: 223-231.
14. Koliatsos VE, Price WL, Pardo CA, Price DL. 1994. Ventral root avulsion: An experimental model of death of adult motor neurons. J Comp Neurol 342: 35-44.
15. Kuno M, Llina's R. 1970. Alterations of synaptic action in chromatolysed motoneurones of the cat. J Physiol 210: 823-838.
16. Lee ST, Chu K, Jung KH, Ko SY, Kim EH, Sinn DI, Lee YS, Lo EH, Kim M, Roh JK. 2005. Granulocyte colony-stimulating factor enhances angiogenesis after focal cerebral ischemia. Brain Res 1058: 120-128.
17. Li L, Wu W, Lin LF, Lei M, Oppenheim RW, Houenou LJ. 1995. Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor. Proc Natl Acad Sci USA 92: 9771-9775.
18. Lindå H, Shupliakov O, Örnung G, Ottersen OP, Storm-Mathisen J, Risling M, Cullheim S. 2000. Ultrastructural evidence for a preferential elimination of glutamateimmunoreactive synaptic terminals from spinal motoneurons after intramedullary axotomy. JComp Neurol 425: 10-23.
19. McCarthy KD, de Vellis J. 1980. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 85: 890-902.
20. Nawashiro H, Messing A, Azzam N, Brenner M. 1998. Mice lacking GFAP are hypersensitive to traumatic cerebrospinal injury. Neuroreport 9: 1691-1696.
21. Nawashiro H, Brenner M, Fukui S, Shima K, Hallenbeck JM. 2000. High susceptibility to cerebral ischemia in GFAP-null mice. J Cereb Blood Flow Metab 20: 1040-1044.
22. Nishio Y, Koda M, Kamada T, Someya Y, Kadota R, Mannoji C, Miyashita T, Okada S, Okawa A, Moriya H, Yamazaki M. 2007. Granulocyte colony stimulating factor attenuates neuronal death and promotes functional recovery after spinal cord injury in mice. J Neuropathol Exp Neurol 66: 724-731.
23. Nógrádi A, Szabó A, Pintér S, Vrbová G. 2007. Delayed riluzole treatment is able to rescue injured rat spinal motoneurons. Neuroscience 144: 431-438.
24. Oliveira ALR, Thams S, Lidman O, Piehl F, Hökfelt T, Kärre K, Lindå H, Cullhem S. 2004. A role for MHC class I moleculles in synaptic plasticity and regeneration of neurons after axotomy. PNAS 101: 17843-17848.
25. Oppenheim RW, Houenou LJ, Johnson JE, Lin LF, Li L, Lo AC, Newsome AL, Prevette DM, Wang S. 1995. Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF. Nature 373: 344-346.
26. Otani N, Nawashiro H, Fukui S, Ooigawa H, Ohsumi A, Toyooka T, Shima K, Gomi H, Brenner M. 2006. Enhanced hippocampal neurodegeneration after traumatic or kainate excitotoxicity in GFAP-null mice. J Clin Neurosci 13: 934-938.
27. Penas C, Pascual-Font A, Mancuso R, Forés J, Casas C, Navarro X. 2011. Sigma receptor agonist 2-(4-morpholinethyl)1 phenylcyclohexanecarboxylate (Pre084) increases GDNF and BiP expression and promotes neuroprotection after root avulsion injury. J Neurotrauma 28: 831-840.
28. Pitzer C, Kruger C, Plaas C, Kirsch F, Dittgen T, Muller R, Laage R, Kastner S, Suess S, Spoelgen R, Henriques A, Ehrenreich H, Schabitz W, Bach A, Schneider A. 2008. Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis. Brain 131: 3335-3347.
29. Schneider A, Kuger C, Steigleder T, Weber D, Pitzer C, Laage R, Aronowski J, Maurer MH, Gassler N, Mier W, Hasselblatt M, Kollmar R, Schwab S, Sommer C, Bach A, Kuhn HG, Schabitz WR. 2005a. The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. J Clin Invest 115: 2083-2098.
30. Schneider A, Kuhn HG, Schabitz WR. 2005b. A role for G-CSF (Granulocyte Colony Stimulating Factor) in the central nervous system. Cell Cycle 4: 1753-1757.
31. Scorisa JM, Zanon RG, Freria CM, de Oliveira AL. 2009. Glatiramer acetate positively influences spinal motoneuron survival and synaptic plasticity after ventral root avulsion. Neurosci Lett 451: 34-39.
32. Solaroglu I, Cahill J, Jadhav V, Zhang JH. 2006. A novel neuroprotectant granulocyte colony stimulating factor. Stroke 37: 1123-1128.
33. Su H, Zhang W, Guo J, Guo A, Yuan Q, Wu W. 2009. Neural progenitor cells enhance the survival and axonal regeneration of injured motoneurons after transplantation into the avulsed ventral horn of adult rats. J Neurotrauma 26: 67-80.
34. Tanaka H, Katoh A, Oguro K, Shimazaki K, Gomi H, Itohara S, Masuzawa T, Kawai N. 2002. Disturbance of hippocampal long-term potentiation after transient ischemia in GFAP deficient mice. J Neurosci Res 67: 11-20.
35. Tao R, Aldskogius H. 1998. Influence of FK506, Cyclosporin A, testosterone and nimodipine on motoneuron survival following axotomy. Restor Neurol Neurosci 12: 239-246.
36. Zavala F, Abad S, Ezine S, Taupin V, Masson A. 2002. G-CSF therapy of ongoing experimental allergic encephalomyelitis via chemokine- and cytokine-based immune deviation. J Immunol 168: 2011-2019.
37. Zhang CG, Welin D, Novikov L, Kellerth JO, Wiberg M, Hart AM. 2005. Motorneuron protection by N-acetyl-cysteine after ventral root avulsion and ventral rhizotomy. Br J Plast Surg 58: 765-773.
38. Zhou LH, Wu W. 2006. Survival of injured spinal motoneurons in adult rat upon treatment with glial cell line-derived neurotrophic factor at 2 weeks but not at 4 weeks after root avulsion. J Neurotrauma 23: 920-927.
39. Ziemssen T, Kümpfel T, Klinkert WE, Neuhaus O, Hohlfeld R. 2002. Glatiramer acetate-specific T-helper 1- and 2-type cell lines produce BDNF: Implications for multiple sclerosis therapy. Brain-derived neurotrophic factor. Brain 125: 2381-2391.