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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 14, 2011, Pages 4203-4205

Discovery of a novel class of 2-aminopyrimidines as CDK1 and CDK2 inhibitors

(3) Lee, Jinho a Kim, Kyoung Hee b Jeong, Shinwu c

a Keimyung University (South Korea)

b LG Chemical Ltd (South Korea)

c UNIVERSITY OF SOUTHERN CALIFORNIA (United States)

Author keywords

2 Aminopyrimidine; CDK; Inhibitor; Pyrrolidine 3,4 diol

Indexed keywords

(3,4) 1 (3 (2 AMINO PYRIMIDIN 4 YL) 4 HYDROXYPHENYL)PYRROLIDINE 3,4 DIOL; CYCLIN DEPENDENT KINASE 1 INHIBITOR; CYCLIN DEPENDENT KINASE 2 INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL GROWTH; CRYSTAL STRUCTURE; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; X RAY;

ANTINEOPLASTIC AGENTS; BINDING SITES; CDC2 PROTEIN KINASE; CELL LINE, TUMOR; COMPUTER SIMULATION; CYCLIN-DEPENDENT KINASE 2; DRUG EVALUATION, PRECLINICAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; PROTEIN KINASE INHIBITORS; PYRIMIDINES;

EID: 79959893500 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.05.081 Document Type: Article

Times cited : (25)

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