Adenoviral vector driven by a minimal Rad51 promoter is selective for p53-deficient tumor cells

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Fong, Vincent ^a   Osterbur, Marika ^a   Capella, Cristina ^a   Kim, Yo El ^a   Hine, Christopher ^b   Gorbunova, Vera ^b   Seluanov, Andrei ^b   Dewhurst, Stephen ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; GANCICLOVIR; LUCIFERASE; PROTEIN P300; PROTEIN P53; RAD51 PROTEIN; SITIMAGENE CERADENOVEC; HISTONE ACETYLTRANSFERASE PCAF;

ARTICLE; BINDING SITE; CANCER CELL CULTURE; CANCER GENE THERAPY; CELL KILLING; CELL SPECIFICITY; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PROMOTER REGION; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; TRANSCRIPTION INITIATION; TRANSCRIPTION INITIATION SITE; TRANSGENE; TUMOR CELL DESTRUCTION; VIRAL GENE DELIVERY SYSTEM; ADENOVIRUS; CELL DEATH; CELL LINE; GENE VECTOR; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NEOPLASM; PATHOLOGY;

ADENOVIRIDAE; BINDING SITES; CELL DEATH; CELL LINE; GENETIC VECTORS; HUMANS; NEOPLASMS; P300-CBP TRANSCRIPTION FACTORS; PROMOTER REGIONS, GENETIC; RAD51 RECOMBINASE; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 83055173822     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028714     Document Type: Article

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