Understanding the α-crystallin cell membrane conjunction

Molecular Vision

Volumn 17, Issue , 2011, Pages 2798-2807

  Su, Shih Ping ^a,b   McArthur, Jason D ^a   Friedrich, Michael G ^b   Truscott, Roger J W ^b   Andrew Aquilina, J ^a  

^a UNIVERSITY OF WOLLONGONG   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALI; ALPHA CRYSTALLIN; RECOMBINANT PROTEIN; UREA;

ADULT; AGED; AGING; ALPHA A CRYSTALLIN GENE; ALPHA B CRYSTALLIN GENE; ANIMAL TISSUE; ARTICLE; CELL JUNCTION; CELL MEMBRANE; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; COW; GENE; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; HUMAN VERSUS ANIMAL COMPARISON; LENS EPITHELIUM; MEMBRANE BINDING; NONHUMAN; PHOSPHOLIPID SYNTHESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN ISOLATION; PROTEIN PURIFICATION; PROTEIN TRANSPORT; WESTERN BLOTTING;

AGED; AGED, 80 AND OVER; AGING; ALKALIES; ALPHA-CRYSTALLIN A CHAIN; ALPHA-CRYSTALLIN B CHAIN; ANIMALS; BLOTTING, WESTERN; CATTLE; CELL FRACTIONATION; CELL MEMBRANE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENT DYES; HUMANS; LENS CORTEX, CRYSTALLINE; LENS NUCLEUS, CRYSTALLINE; MEMBRANE PROTEINS; MIDDLE AGED; PROTEIN BINDING; TISSUE EXTRACTS; UREA;

EID: 83055170897     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Garland DL, Duglas-Tabor Y, Jimenez-Asensio J, Datiles MB, Magno B. The nucleus of the human lens: demonstration of a highly characteristic protein pattern by two-dimensional electrophoresis and introduction of a new method of lens dissection. Exp Eye Res 1996; 62:285-91. [PMID: 8690038]
2. Kuszak JR, Zoltoski RK, Tiedemann CE. Development of lens sutures. Int J Dev Biol 2004; 48:889-902. [PMID: 15558480]
3. Horwitz J. Alpha-Crystallin can function as a molecular chaperone. Proc Natl Acad Sci USA 1992; 89:10449-53. [PMID: 1438232]
4. Rao PV, Huang QL, Horwitz J, Zigler JS Jr. Evidence that alpha-crystallin prevents non-specific protein aggregation in the intact eye lens. Biochim Biophys Acta 1995; 1245:439-47. [PMID: 8541324]
5. Lynnerup N, Kjeldsen H, Heegaard S, Jacobsen C, Heinemeier J. Radiocarbon dating of the human eye lens crystallines reveal proteins without carbon turnover throughout life. PLoS One 2008; 3:e1529. [PMID: 18231610]
6. Hoehenwarter W, Klose J, Jungblut PR. Eye Lens Proteomics. Amino Acids 2006; 30:369-89. [PMID: 16583312]
7. Wilmarth PA, Tanner S, Dasari S, Nagalla SR, Riviere MA, Bafna V, Pevzner PA, David LL. Age-related changes in human crystallins determined from comparative analysis of post-translational modifications in young and aged lens: does deamidation contribute to crystallin insolubility? J Proteome Res 2006; 5:2554-66. [PMID: 17022627]
8. Harrington V, McCall S, Huynh S, Srivastava K, Srivastava OP. Crystallins in water soluble-high molecular weight protein fractions and water insoluble protein fractions in aging and cataractous human lenses. Mol Vis 2004; 10:476-89. [PMID: 15303090]
9. Hanson SR, Hasan A, Smith DL, Smith JB. The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage. Exp Eye Res 2000; 71:195-207. [PMID: 10930324]
10. Truscott RJ, Zhu X. Presbyopia and cataract: a question of heat and time. Prog Retin Eye Res 2010; 29:487-99. [PMID: 20472092]
11. Aarts HJ, Lubsen NH, Schoenmakers JG. Crystallin gene expression during rat lens development. Eur J Biochem 1989; 183:31-6. [PMID: 2753045]
12. Su S-P, McArthur JD, Truscott RJ, Aquilina JA. Truncation, cross-linking and interaction of crystallins and intermediate filament proteins in the aging human lens. Biochim Biophys Acta 2011; 1814:647-56. [PMID: 21447408]
13. Heys KR, Friedrich MG, Truscott RJW. Presbyopia and heat: changes associated with aging of the human lens suggest a functional role for the small heat shock protein, alphacrystallin, in maintaining lens flexibility. Aging Cell 2007; 6:807-15. [PMID: 17973972]
14. McFall-Ngai MJ, Ding LL, Takemoto LJ, Horwitz J. Spatial and temporal mapping of the age-related changes in human lens crystallins. Exp Eye Res 1985; 41:745-58. [PMID: 3830737]
15. Roy D, Spector A. Absence of low-molecular-weight alpha crystallin in nuclear region of old human lenses. Proc Natl Acad Sci USA 1976; 73:3484-7. [PMID: 1068460]
16. Lampi KJ, Ma Z, Hanson SR, Azuma M, Shih M, Shearer TR, Smith DL, Smith JB, David LL. Age-related changes in human lens crystallins identified by two-dimensional electrophoresis and mass spectrometry. Exp Eye Res 1998; 67:31-43. [PMID: 9702176]
17. Srivastava OP, Srivastava K, Silney C. Levels of crystallin fragments and identification of their origin in water soluble high molecular weight (HMW) proteins of human lenses. Curr Eye Res 1996; 15:511-20. [PMID: 8670752]
18. Ma Z, Hanson SR, Lampi KJ, David LL, Smith DL, Smith JB. Age-related changes in human lens crystallins identified by HPLC and mass spectrometry. Exp Eye Res 1998; 67:21-30. [PMID: 9702175]
19. Fu SC, Su SW, Wagner BJ, Hart R. Characterization of lens proteins. IV. Analysis of soluble high molecular weight protein aggregates in human lenses. Exp Eye Res 1984; 38:485-95. [PMID: 6745324]
20. Boyle DL, Takemoto L. EM immunolocalization of alphacrystallins: association with the plasma membrane from normal and cataractous human lenses. Curr Eye Res 1996; 15:577-82. [PMID: 8670759]
21. Cenedella RJ, Fleschner CR. Selective association of crystallins with lens 'native' membrane during dynamic cataractogenesis. Curr Eye Res 1992; 11:801-15. [PMID: 1424724]
22. Friedrich MG, Truscott RJ. Large-scale binding of alphacrystallin to cell membranes of aged normal human lenses: a phenomenon that can be induced by mild thermal stress. Invest Ophthalmol Vis Sci 2010; 51:5145-52. [PMID: 20435594]
23. Friedrich MG, Truscott RJ. Membrane association of proteins in the aging human lens: profound changes take place in the fifth decade of life. Invest Ophthalmol Vis Sci 2009; 50:4786-93. [PMID: 19458333]
24. Truscott RJ. Age-related nuclear cataract-oxidation is the key. Exp Eye Res 2005; 80:709-25. [PMID: 15862178]
25. Chandrasekher G, Cenedella RJ. Protein associated with human lens 'native' membrane during aging and cataract formation. Exp Eye Res 1995; 60:707-17. [PMID: 7641853]
26. Cobb BA, Petrash JM. alpha-Crystallin chaperone-like activity and membrane binding in age-related cataracts. Biochemistry 2002; 41:483-90. [PMID: 11781086]
27. Grami V, Marrero Y, Huang L, Tang D, Yappert MC, Borchman D. alpha-Crystallin binding in vitro to lipids from clear human lenses. Exp Eye Res 2005; 81:138-46. [PMID: 15967437]
28. Tang D, Borchman D, Yappert MC, Cenedella RJ. Influence of cholesterol on the interaction of alpha-crystallin with phospholipids. Exp Eye Res 1998; 66:559-67. [PMID: 9628803]
29. Chandrasekher G, Cenedella RJ. Properties of alpha-crystallin bound to lens membrane: probing organization at the membrane surface. Exp Eye Res 1997; 64:423-30. [PMID: 9196394]
30. Cobb BA, Petrash JM. Characterization of alpha-crystallinplasma membrane binding. J Biol Chem 2000; 275:6664-72. [PMID: 10692476]
31. Russell P, Robison WG Jr, Kinoshita JH. A new method for rapid isolation of the intrinsic membrane proteins from lens. Exp Eye Res 1981; 32:511-6. [PMID: 6786906]
32. Deeley JM, Mitchell TW, Wei X, Korth J, Nealon JR, Blanksby SJ, Truscott RJ. Human lens lipids differ markedly from those of commonly used experimental animals. Biochim Biophys Acta 2008; 1781:288-98. [PMID: 6786906]
33. Brügger B, Erben G, Sandhoff R, Wieland FT, Lehmann WD. Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry. Proc Natl Acad Sci USA 1997; 94:2339-44. [PMID: 9122196]
34. Horwitz J, Huang Q-L, Ding L, Bova MP. Lens alpha-crystallin: chaperone-like properties. Methods Enzymol 1998; 290:365-83. [PMID: 9534176]
35. Santhoshkumar P, Udupa P, Murugesan R, Sharma KK. Significance of interactions of low molecular weight crystallin fragments in lens aging and cataract formation. J Biol Chem 2008; 283:8477-85. [PMID: 18227073]
36. Su S-P, McArthur JD, Aquilina JA. Localization of low molecular weight crystallin peptides in the aging human lens using a MALDI mass spectrometry imaging approach. Exp Eye Res 2010; 91:97-103. [PMID: 20433829]
37. Grey AC, Schey KL. Age-related changes in the spatial distribution of human lens alpha-crystallin products by MALDI imaging mass spectrometry. Invest Ophthalmol Vis Sci 2009; 50:4319-29. [PMID: 19387068]
38. Sweeney MHJ, Truscott RJW. An impediment to glutathione diffusion in older normal human lenses: a possible precondition for nuclear cataract. Exp Eye Res 1998; 67:587-95. [PMID: 9878221]
39. Truscott RJ. Age-related nuclear cataract: a lens transport problem. Ophthalmic Res 2000; 32:185-94. [PMID: 10971179]
40. Ifeanyi F, Takemoto L. Differential binding of alpha-crystallins to bovine lens membrane. Exp Eye Res 1989; 49:143-7. [PMID: 2759187]
41. Mulders JW, Stokkermans J, Leunissen JA, Benedetti EL, Bloemendal H, de Jong WW. Interaction of alpha-crystallin with lens plasma membranes. Affinity for MP26. Eur J Biochem 1985; 152:721-8. [PMID: 4054130]
42. Ifeanyi F, Takemoto L. Specificity of alpha crystallin binding to the lens membrane. Curr Eye Res 1990; 9:259-65. [PMID: 2347203]
43. Bloemendal H, Berbers GA, De Jong WW, Ramaekers FC, Vermorken AJ, Dunia I, Benedetti EL. Interaction of crystallins with the cytoskeletal-plasma membrane complex of the bovine lens. Ciba Found Symp 1984; 106:177-90. [PMID: 6568972]
44. Cenedella RJ, Chandrasekher G. High capacity binding of alpha crystallins to various bovine lens membrane preparations. Curr Eye Res 1993; 12:1025-38. [PMID: 8306713]
45. Carter JM, Hutcheson AM, Quinlan RA. In vitro studies on the assembly properties of the lens proteins CP49, CP115: coassembly with alpha-crystallin but not with vimentin. Exp Eye Res 1995; 60:181-92. [PMID: 7781747]
46. Quinlan RA, Carter JM, Sandilands A, Prescott AR. The beaded filament of the eye lens: an unexpected key to intermediate filament structure and function. Trends Cell Biol 1996; 6:123-6. [PMID: 15157473]
47. Schey KL, Gutierrez DB, Wang Z, Wei J, Grey AC. Novel fatty acid acylation of lens integral membrane protein aquaporin-0. Biochemistry 2010; 49:9858-65. [PMID: 20942504]
48. Reddy GB, Das KP, Petrash JM, Surewicz WK. Temperaturedependent chaperone activity and structural properties of human alphaA-and alphaB-crystallins. J Biol Chem 2000; 275:4565-70. [PMID: 10671481]
49. Santhoshkumar P, Udupa P, Murugesan R, Sharma KK. Significance of interactions of low molecular weight crystallin fragments in lens aging and cataract formation. J Biol Chem 2008; 283:8477-85. [PMID: 18227073]
50. Zaslavsky, BYU; Borovskaya, AA.; Rogozhin, SV. Effect of lipid composition on hydrophobic properties of liposomes. Mol Cell Biochem 1984; 60:131-6. [PMID: 6200761]
51. Derham BK, Harding JJ. Alpha-crystallin as a molecular chaperone. Prog Retin Eye Res 1999; 18:463-509. [PMID: 10217480]
52. Aquilina JA, Watt SJ. The N-terminal domain of alphaBcrystallin is protected from proteolysis by bound substrate. Biochem Biophys Res Commun 2007; 353:1115-20. [PMID: 17207466]
53. Hughes JR, Deeley JM, Blanksby SJ, Leisch F, Ellis SR, Truscott RJW, Mitchell TW. Instability of the cellular lipidome with age. Age (Dordr). 2011 [PMID: 21894448]