Presbyopia and heat: Changes associated with aging of the human lens suggest a functional role for the small heat shock protein, α-crystallin, in maintaining lens flexibility

Aging Cell

Volumn 6, Issue 6, 2007, Pages 807-815

  Heys, Karl R ^a,b   Friedrich, Michael G ^a,b   Truscott, Roger J W ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

Crystallin; Aging; Lens stiffness; Presbyopia; Protein denaturation; Thermal aggregation

Indexed keywords

ALPHA CRYSTALLIN; CHAPERONE; SMALL HEAT SHOCK PROTEIN;

AGING; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; HEAT; HIGH TEMPERATURE; HUMAN; HUMAN CELL; HUMAN TISSUE; LENS FIBER; MOLECULAR WEIGHT; NONHUMAN; PRESBYOPIA; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; SWINE;

AGING; ALPHA-CRYSTALLINS; ANIMALS; HEAT; HEAT-SHOCK PROTEINS, SMALL; HUMANS; LENS, CRYSTALLINE; MIDDLE AGED; PLIABILITY; PRESBYOPIA; SWINE;

SUIDAE;

EID: 36249023238     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2007.00342.x     Document Type: Article

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