Role of Apoptosis in Adverse Ventricular Remodeling

Heart Failure Clinics

Volumn 8, Issue 1, 2012, Pages 79-86

  Abbate, Antonio ^a   Narula, Jagat ^b  

^a VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Caspase; Heart failure; Ventricular remodeling

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; LIPOCORTIN 5; PHOSPHATIDYLSERINE; PROTEIN BAX; PROTEIN BCL 2; SURVIVIN; X LINKED INHIBITOR OF APOPTOSIS;

ACUTE HEART INFARCTION; APOPTOSIS; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; CARDIAC PATIENT; CELL DEATH; CELL DEGENERATION; CELL ENERGY; CELL STRESS; CONGESTIVE CARDIOMYOPATHY; DISEASE CLASSIFICATION; DISEASE COURSE; DISEASE SEVERITY; DNA FRAGMENTATION; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; HEART FAILURE; HEART MUSCLE; HEART MUSCLE CELL; HEART VENTRICLE REMODELING; HISTOPATHOLOGY; HUMAN; MICROSCOPY; MOLECULAR IMAGING; REVIEW;

ANIMALS; APOPTOSIS; DISEASE PROGRESSION; HEART FAILURE; HUMANS; MYOCARDIUM; VENTRICULAR REMODELING;

EID: 82955246193     PISSN: 15517136     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hfc.2011.08.010     Document Type: Review

References (43)

1. Jessup M., Abraham W.T., Casey D.E., et al. 2009 focused update: ACCF/AHA guidelines for the diagnosis and management of heart failure in adults. Circulation 2009, 119:1977-2016.
2. Greenberg H., Mc Master P., Dwyer E.M. Left ventricular dysfunction after acute myocardial infarction: results of a prospective multicenter study. J Am Coll Cardiol 1984, 5:867-874. Multicenter Post-Infarction Research Group.
3. Abbate A., Biondi-Zoccai G.G., Baldi A. Pathophysiologic role of myocardial apoptosis in post-infarction left ventricular remodeling. J Cell Physiol 2002, 193:145-153.
4. Reimer K.A., Jennings R.B. The " wave front phenomenon" of myocardial ischemic cell death. II. Transmural progression of necrosis within the framework of ischemic bed size (myocardium at risk) and collateral flow. Lab Invest 1979, 40:633-642.
5. Hutchins G.M., Bulkley B.H. Infarct expansion versus extension: two different complications of acute myocardial infarction. Am J Cardiol 1978, 41:1127-1131.
6. Jackson B.M., Gorman J.H., Moainie S.L., et al. Extension of borderzone myocardium in postinfarction dilated cardiomyopathy. J Am Coll Cardiol 2002, 40:1160-1167.
7. Dispersyn G.D., Mesotten L., Meuris B., et al. Dissociation of cardiomyocyte apoptosis and dedifferentiation in infarct border zones. Eur Heart J 2002, 23:849-857.
8. Canty J.M., Suzuki G. Heterogeneity of apoptosis and myolysis in coronary microembolization: a competition between programmed cell death and programmed cell survival. Eur Heart J 2002, 23:838-840.
9. Narula N., Narula J., Zhang P.J., et al. Is the myofibrillarlytic myocyte a forme frusta apoptotic myocyte?. Ann Thorac Surg 2005, 79:1333-1337.
10. Gottlieb R.A., Carreira R.S. Autophagy in health and disease. Am J Physiol Cell Physiol 2010, 299:C203-C210.
11. Elsasser A., Vogt A.M., Nef H., et al. Human hibernating myocardium is jeopardized by apoptotic and autophagic cell death. J Am Coll Cardiol 2004, 43:2191-2199.
12. Chandrashekhar Y., Narula J. Death hath a thousand doors to let out life. Circ Res 2003, 92:710-714.
13. Narula J., Haider N., Virmani R., et al. Apoptosis in myocytes in end stage heart failure. N Engl J Med 1996, 335:1182-1189.
14. Narula J., Pandley P., Arbustini E., et al. Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy. Proc Natl Acad Sci U S A 1999, 96:8144-8149.
15. Baldi A., Abbate A., Bussani R., et al. Apoptosis and post-infarction left ventricular remodeling. J Mol Cell Cardiol 2002, 34:165-174.
16. Scheubel R.J., Bartling B., Simm A., et al. Apoptotic pathway activation from mitochondria and death receptors without caspase-3 cleavage in failing human myocardium: fragile balance of myocyte survival?. J Am Coll Cardiol 2002, 39:481-488.
17. Ruetten H., Badorff C., Ihling C., et al. Inhibition of caspase-3 improves contractile recover of stunned myocardium, independent of apoptosis-inhibitory effects. J Am Coll Cardiol 2001, 38:2063-2070.
18. Kroemer G., Galluzzi L., Vandenabeele P., et al. Classification of cell death: recommendations of the nomenclature committee on cell death 2009. Cell Death Differ 2009, 16:3-11.
19. Kerr J.F., Wyllie A.H., Curie A.R. Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics. Br J Cancer 1972, 26:239-256.
20. Anversa P., Olivetti G., Capasso J.M. Cellular basis of ventricular remodeling after myocardial infarction. Am J Cardiol 1991, 68:7D-16D.
21. Olivetti G., Abbi R., Quaini F., et al. Apoptosis in the failing human heart. N Engl J Med 1997, 336:1131-1141.
22. Anselmi A., Gaudino M., Baldi A., et al. Role of apoptosis in pressure-overload cardiomyopathy. J Cardiovasc Med 2008, 9:227-232.
23. Whelan R.S., Kaplinskiy V., Kitsis R.N. Cell death in the pathogenesis of heart disease: mechanisms and significance. Annu Rev Physiol 2010, 72:19-44.
24. Wencker D., Chandra M., Nguyen K., et al. A mechanistic role for cardiac myocyte apoptosis in heart failure. J Clin Invest 2003, 111:1497-1504.
25. Abbate A., Biondi-Zoccai G.G., Bussani R., et al. Increased myocardial apoptosis in patients with unfavorable left ventricular remodeling and early symptomatic post-infarction heart failure. J Am Coll Cardiol 2003, 41:753-760.
26. Olivetti G., Quaini F., Sala R., et al. Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart. J Mol Cell Cardiol 1996, 28:2005-2016.
27. Abbate A., Bussani R., Sinagra G., et al. Right ventricular cardiomyocyte apoptosis in patients with acute myocardial infarction of the left ventricular wall. Am J Cardiol 2008, 102:658-662.
28. Bussani R., Abbate A., Biondi-Zoccai G.G., et al. Right ventricular dilatation after left ventricular acute myocardial infarction is predictive of extremely high peri-infarctual apoptosis at postmortem examination in humans. J Clin Pathol 2003, 56:672-676.
29. Abbate A., Bussani R., Biondi-Zoccai G.G., et al. Persistent infarct-related artery occlusion is associated with an increased myocardial apoptosis at postmortem examination in humans late after an acute myocardial infarction. Circulation 2002, 106:1051-1054.
30. Bondarenko O., Beek A.M., Twisk J.W., et al. Time course of functional recovery after revascularization of hibernating myocardium: a contrast-enhanced cardiovascular magnetic resonance study. Eur Heart J 2008, 29:2000-2005.
31. Saraste A., Pulkki K., Kallajoki M., et al. Cardiomyocyte apoptosis and progression of heart failure to transplantation. Eur J Clin Invest 1999, 29:380-386.
32. Kietselaer B.L., Reutelingsperger C.P., Boersma H.H., et al. Noninvasive detection of programmed cell loss with 99mTc-labeled annexin A5 in heart failure. J Nucl Med 2007, 48:562-567.
33. Heusch G. Hibernating myocardium. Physiol Rev 1998, 78:1055-1085.
34. Communal C., Sumandea M., Solaro J.R., et al. Functional consequences of apoptosis in cardiac myocytes: myofibrillar proteins are targets for caspase-3. Circulation (Abstract) 2001, 104:2-162.
35. Haider N., Arbustini E., Gupta S., et al. Concurrent upregulation of endogenous proapoptotic and antiapoptotic factors in failing human hearts. Nat Clin Pract Cardiovasc Med 2009, 6:250-261.
36. Narula J., Arbustini E., Chandrashekhar Y., et al. Apoptosis and the systolic dysfunction in congestive heart failure. Story of apoptosis interruptus and zombie myocytes. Cardiol Clin 2001, 19:113-126.
37. Santini D., Abbate A., Scarpa S., et al. Surviving acute myocardial infarction: survivin expression in viable cardiomyocytes after infarction. J Clin Pathol 2004, 57:1321-1324.
38. Severino A., Campioni M., Straino S., et al. Identification of protein disulfide isomerase as a cardiomyocyte survival factor in ischemic cardiomyopathy. J Am Coll Cardiol 2007, 50:1029-1037.
39. Narula J., Young J.B. Imaging heart failure: premonition to prevention in predisposed. Heart Fail Clin 2006, 2:ix-x.
40. Velazquez E.J., Lee K.L., Deja M.A., et al. Coronary-artery bypass surgery in patients with left ventricular dysfunction. N Engl J Med 2011, 364:1607-1616.
41. Abbate A., Bussani R., Amin M.S., et al. Acute myocardial infarction and heart failure: role of apoptosis. Int J Biochem Cell Biol 2006, 38:1834-1840.
42. Chandrashekhar Y., Sen S., Anway R., et al. Long-term caspase inhibition ameliorates apoptosis, reduces myocardial troponin-I cleavage, protects left ventricular function, and attenuates remodeling in rats with myocardial infarction. J Am Coll Cardiol 2004, 43:295-301.
43. Hofstra L., Liem I.H., Dumont E.A., et al. Visualisation of cell death in vivo in patients with acute myocardial infarction. Lancet 2000, 356:209-212.