Histological evolution of chronic wounds under negative pressure therapy

Journal of Plastic, Reconstructive and Aesthetic Surgery

Volumn 65, Issue 1, 2012, Pages 91-99

  Bassetto, Franco ^a   Lancerotto, Luca ^a   Salmaso, Roberto ^b   Pandis, Laura ^a   Pajardi, Giorgio ^c   Schiavon, Mauro ^d   Tiengo, Cesare ^a   Vindigni, Vincenzo ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY HOSPITAL OF PADOVA   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d UNIVERSITY HOSPITAL OF UDINE   (Italy)

Author keywords

Negative pressure therapy; Ulcer; VAC Therapy; Vacuum; Wound

Indexed keywords

CD31 ANTIGEN; CD45 ANTIGEN; CD68 ANTIGEN; CYCLINE;

ARTICLE; CHRONIC WOUND; EDEMA; GRANULATION TISSUE; HISTOLOGY; HUMAN; HUMAN TISSUE; INFLAMMATION; PRIORITY JOURNAL; PUNCH BIOPSY; VACUUM ASSISTED CLOSURE;

ADULT; AGED; AGED, 80 AND OVER; BIOPSY, NEEDLE; CHRONIC DISEASE; FEMALE; FOLLOW-UP STUDIES; GRANULATION TISSUE; HUMANS; IMMUNOHISTOCHEMISTRY; LEG ULCER; MALE; MIDDLE AGED; NEGATIVE-PRESSURE WOUND THERAPY; TIME FACTORS; TREATMENT OUTCOME; WOUND HEALING;

EID: 82955195426     PISSN: 17486815     EISSN: 18780539     Source Type: Journal    
DOI: 10.1016/j.bjps.2011.08.016     Document Type: Article

References (27)

1. M.J. Morykwas, J. Simpson, and K. Punger Vacuum-assisted closure: state of basic research and physiologic foundation Plast Reconstr Surg 117 2006 121S 126S (Pubitemid 44317776)
2. D.P. Orgill, E.K. Manders, and B.E. Sumpio The mechanisms of action of vacuum assisted closure: More to learn Surgery 146 2009 40 51
3. C. Torbrand, M. Ugander, and H. Engblom Wound contraction and macro-deformation during negative pressure therapy of sternotomy wounds J Cardiothorac Surg 5 2010 75
4. C.M. Moues, M.C. Vos, and G.J. van den Bemd Bacterial load in relation to vacuum-assisted closure wound therapy: A prospective randomized trial Wound Repair Regen 12 2004 11 17 (Pubitemid 38249130)
5. T. Weed, C. Ratliff, and D.B. Drake Quantifying bacterial bioburden during negative pressure wound therapy: does the wound VAC enhance bacterial clearance? Ann Plast Surg 52 2004 276 279 discussion 279-80
6. A. Braakenburg, M.C. Obdeijn, and R. Feitz The clinical efficacy and cost effectiveness of the vacuum-assisted closure technique in the management of acute and chronic wounds: a randomized controlled trial Plast Reconstr Surg 118 2006 390 397 discussion 398-400 (Pubitemid 44162045)
7. S.S. Scherer, G. Pietramaggiori, and J.C. Mathews Short periodic applications of the vacuum-assisted closure device cause an extended tissue response in the diabetic mouse model Plast Reconstr Surg 124 2009 1458 1465
8. M. Malmsjo, S. Lindstedt, and R. Ingemansson Influence on pressure transduction when using different drainage techniques and wound fillers (foam and gauze) for negative pressure wound therapy Int Wound J 7 2010 406 412
9. M.J. Morykwas, L.C. Argenta, and E.I. Shelton-Brown Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation Ann Plast Surg 38 1997 553 562 (Pubitemid 27251299)
10. L. Labler, M. Rancan, and L. Mica Vacuum-assisted closure therapy increases local interleukin-8 and vascular endothelial growth factor levels in traumatic wounds J Trauma 66 2009 749 757
11. V. Saxena, C.W. Hwang, and S. Huang Vacuum-assisted closure: microdeformations of wounds and cell proliferation Plast Reconstr Surg 114 2004 1086 1096 discussion 1097-8 (Pubitemid 40362027)
12. S. Huang, and D.E. Ingber Shape-dependent control of cell growth, differentiation, and apoptosis: switching between attractors in cell regulatory networks Exp Cell Res. 261 2000 91 103
13. G. Pietramaggiori, P. Liu, and S.S. Scherer Tensile forces stimulate vascular remodeling and epidermal cell proliferation in living skin Ann Surg 246 2007 896 902 (Pubitemid 350035668)
14. S.S. Scherer, G. Pietramaggiori, and J.C. Mathews The mechanism of action of the vacuum-assisted closure device Plast Reconstr Surg 122 2008 786 797
15. M.S. Chin, R. Ogawa, and L. Lancerotto In vivo acceleration of skin growth using a servo-controlled stretching device Tissue Eng Part C. Methods 16 2010 397 405
16. M.S. Chin, L. Lancerotto, and D.L. Helm Analysis of neuropeptides in stretched skin Plast Reconstr Surg 124 2009 102 113
17. S.Z. Chen, J. Li, and X.Y. Li Effects of vacuum-assisted closure on wound microcirculation: an experimental study Asian J Surg 28 2005 211 217 (Pubitemid 41152891)
18. G.C. Murphey, B.R. Macias, and A.R. Hargens Depth of penetration of negative pressure wound therapy into underlying tissues Wound Repair Regen 17 2009 113 117
19. R. Wilkes, Y. Zhao, and K. Cunningham 3D strain measurement in soft tissue: demonstration of a novel inverse finite element model algorithm on MicroCT images of a tissue phantom exposed to negative pressure wound therapy J Mech Behav Biomed Mater 2 2009 272 287
20. N. Kairinos, M. Solomons, and D.A. Hudson The paradox of negative pressure wound therapy-in vitro studies J Plast Reconstr Aesthet Surg 63 2010 174 179
21. N. Kairinos, M. Solomons, and D.A. Hudson Negative-pressure wound therapy I: the paradox of negative-pressure wound therapy Plast Reconstr Surg 123 2009 589 598 discussion 599-600
22. N. Kairinos, A.M. Voogd, and P.H. Botha Negative-pressure wound therapy II: negative-pressure wound therapy and increased perfusion. just an illusion? Plast Reconstr Surg 123 2009 601 612
23. A.P. Labanaris, E. Polykandriotis, and R.E. Horch The effect of vacuum-assisted closure on lymph vessels in chronic wounds J Plast Reconstr Aesthet Surg 62 2009 1068 1075
24. S. Jacobs, D.A. Simhaee, and A. Marsano Efficacy and mechanisms of vacuum-assisted closure (VAC) therapy in promoting wound healing: a rodent model J Plast Reconstr Aesthet Surg 62 2009 1331 1338
25. A.J. Singer, and R.A. Clark Cutaneous wound healing N Engl J Med 341 1999 738 746 (Pubitemid 29407375)
26. G. Broughton 2nd, J.E. Janis, and C.E. Attinger Wound healing: an overview Plast Reconstr Surg 117 2006 1e-S 32e-S (Pubitemid 44334746)
27. A. Korber, T. Franckson, and S. Grabbe Vacuum assisted closure device improves the take of mesh grafts in chronic leg ulcer patients Dermatology 216 2008 250 256 (Pubitemid 351416729)