The mechanism of action of the vacuum-assisted closure device

Plastic and Reconstructive Surgery

Volumn 122, Issue 3, 2008, Pages 786-797

  Scherer, Sandra Saja ^a   Pietramaggiori, Giorgio ^a   Mathews, Jasmine C ^a   Prsa, Michael J ^a   Huang, Sui ^a   Orgill, Dennis P ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYURETHAN FOAM; CELL ADHESION MOLECULE; POLYURETHAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATMOSPHERIC PRESSURE; BLOOD VESSEL; CELL NUCLEUS; CELL PROLIFERATION; COMPRESSION; CONTROLLED STUDY; DEFORMITY; DENSITY; DIABETES MELLITUS; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; OCCLUSIVE DRESSING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SPLINT; VACUUM ASSISTED CLOSURE; VASCULARIZATION; WOUND; ANIMAL; CELL DIVISION; COMPARATIVE STUDY; EXPERIMENTAL DIABETES MELLITUS; GROWTH, DEVELOPMENT AND AGING; INJURY; INSTRUMENTATION; KINETICS; MALE; PHYSIOLOGY; WOUND HEALING;

ANIMALS; BLOOD VESSELS; CELL ADHESION MOLECULES; CELL DIVISION; DIABETES MELLITUS, EXPERIMENTAL; IMMUNOHISTOCHEMISTRY; KINETICS; MALE; MICE; NEGATIVE-PRESSURE WOUND THERAPY; OCCLUSIVE DRESSINGS; POLYURETHANES; WOUND HEALING; WOUNDS AND INJURIES;

EID: 52049126868     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/PRS.0b013e31818237ac     Document Type: Article

References (19)

1. Singh, N., Armstrong, D. G., and Lipsky, B. A. Preventing foot ulcers in patients with diabetes. J.A.M.A. 293: 217, 2005.
2. Campbell, L. V., Graham, A. R., Kidd, R. M., Molloy, H. F., O'Rourke, S. R., and Colagiuri, S. The lower limb in people with diabetes: Position statement of the Australian Diabetes Society. Med. J. Aust. 173: 369, 2000.
3. Argenta, L. C., and Morykwas, M. J. Vacuum-assisted closure: A new method for wound control and treatment. Clinical experience. Ann. Plast. Surg. 38: 563, 1997.
4. Armstrong, D. G., Lavery, L. A., Abu-Rumman, P., et al. Outcomes of subatmospheric pressure dressing therapy on wounds of the diabetic foot. Ostomy Wound Manage. 48: 64, 2002.
5. Orgill, D. P. Utilizing negative pressure wound therapy on open chest/sternotomy wounds. Ostomy Wound Manage 50 (11A Suppl.): 15S, 2004.
6. Orgill, D. W., Charles, G. A., Neil, E. B., et al. Guidelines for treatment of complex chest wounds with negative pressure wound therapy. Wounds (Suppl.): 1, 2004.
7. Marks, M. W., Argenta, L. C., and Thornton, J. W. Rapid expansion: Experimental and clinical experience. Clin. Plast. Surg. 14: 455, 1987.
8. Morykwas, M. J., Argenta, L. C., Shelton-Brown, E. I., and McGuirt, W. Vacuum-assisted closure: A new method for wound control and treatment. Animal studies and basic foundation. Ann. Plast. Surg. 38: 553, 1997.
9. Fabian, T. S., Kaufman, H. J., Lett, E. D., et al. The evaluation of subatmospheric pressure and hyperbaric oxygen in ischemic full-thickness wound healing. Am. Surg. 66: 1136, 2000.
10. Moues, C. M., Vos, M. C., van den Bemd, G. J., Stijnen, T., and Hovius, S. E. Bacterial load in relation to vacuum-assisted closure wound therapy: A prospective randomized trial. Wound Repair Regen. 12: 11, 2004.
11. Greene, A. K., Puder, M., Roy, R., et al. Microdeformational wound therapy: Effects on angiogenesis and matrix metal-loproteinases in chronic wounds of 3 debilitated patients. Ann. Plast. Surg. 56: 418, 2006.
12. Kilpadi, D. V., Bower, C. E., Reade, C. C., et al. Effect of vacuum assisted closure therapy on early systemic cytokine levels in a swine model. Wound Repair Regen. 14: 210, 2006.
13. Saldalamacchia, G., Lapice, E., Cuomo, V., et al. A controlled study of the use of autologous platelet gel for the treatment of diabetic foot ulcers. Nutr. Metab. Cardiovasc. Dis. 14: 395, 2004.
14. Pietramaggiori, G., Kaipainen, A., Czeczuga, J. M., Wagner, C. T., and Orgill, D. P. Freeze-dried platelet-rich plasma shows beneficial healing properties in chronic wounds. Wound Repair Regen. 14: 573, 2006.
15. Pietramaggiori, G., Kaipainen, A., Ho, D., et al. Trehalose lyophilized platelets for wound healing. Wound Repair Regen. 15: 213, 2007.
16. Saxena, V., Hwang, C. W., Huang, S., Eichbaum, Q., Ingber, D., and Orgill, D. P. Vacuum-assisted closure: Microdefor-mations of wounds and cell proliferation. Plast. Reconstr. Surg. 114: 1086, 2004.
17. Martin, P. Wound healing: Aiming for perfect skin regeneration. Science 276: 75, 1997.
18. Ingber, D. E., and Folkman, J. Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: Role of extracellular matrix. J. Cell Biol. 109: 317, 1989.
19. Pietramaggiori, G., Liu, P., Scherer, S. S., et al. Tensile forces stimulate vascular remodeling and epidermal cell proliferation in living skin. Ann. Surg. 246: 896, 2007.