Functional and transcriptional induction of aquaporin-1 gene by hypoxia; analysis of promoter and role of HIF-1α

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Abreu Rodríguez, Irene ^a,e   Sánchez Silva, Rocío ^a   Martins, Ana Paula ^b   Soveral, Graça ^b,c   Toledo Aral, Juan José ^a,d   López Barneo, José ^a,d   Echevarría, Miriam ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^b UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^c RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^d CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^e UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN 1; COBALT CHLORIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LUCIFERASE; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; WATER;

ANIMAL CELL; ANIMAL TISSUE; AQUAPORIN 1 GENE; ARTICLE; BRAIN TISSUE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE; GENE DELETION; GENE INDUCTION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GLIOMA CELL; HYPOXIA; IN VITRO STUDY; INCUBATION TIME; LIGHT SCATTERING; LUNG PARENCHYMA; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; RAT; TRANSCRIPTION REGULATION; UPREGULATION; WATER PERMEABILITY; ANIMAL; BINDING SITE; CELL HYPOXIA; CELL MEMBRANE PERMEABILITY; DOWN REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PROTEIN STABILITY; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

ANIMALS; AQUAPORIN 1; BINDING SITES; CELL HYPOXIA; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; DOWN-REGULATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; PROMOTER REGIONS, GENETIC; PROTEIN STABILITY; RATS; RNA, MESSENGER; SEQUENCE DELETION; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION; WATER;

EID: 82955194935     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028385     Document Type: Article

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