The NOTCH pathway contributes to cell fate decision in myelopoiesis

Haematologica

Volumn 96, Issue 12, 2011, Pages 1753-1760

  Bugeon, Laurence ^a   Taylor, Harriet B ^a   Progatzky, Fränze ^a   Lin, Michelle I ^b   Ellis, Charles D ^a   Welsh, Natalie ^a   Smith, Emma ^a   Vargesson, Neil ^a   Gray, Caroline ^c   Renshaw, Stephen A ^c   Chico, Timothy J A ^c   Zon, Leonard I ^b   Lamb, Jonathan ^a   Dallman, Margaret J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Cell fate; Hematopoiesis; Myelopoiesis; NOTCH signaling

Indexed keywords

GREEN FLUORESCENT PROTEIN; MUTANT PROTEIN; MYELOPEROXIDASE; NOTCH RECEPTOR; NOTCH1A RECEPTOR; PROTEIN DELTAC; RED FLUORESCENT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL COUNT; CELL FATE; CELL FUNCTION; CELL MATURATION; CELL MIGRATION; CONTROLLED STUDY; EMBRYO; FERTILIZATION; FLOW CYTOMETRY; IN SITU HYBRIDIZATION; KIDNEY; MOLECULAR PROBE; MONOCYTE; MYELOPOIESIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TRANSGENICS; WILD TYPE; WOUND HEALING;

ANIMALS; EMBRYO, NONMAMMALIAN; HOMEODOMAIN PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MYELOPOIESIS; NERVE TISSUE PROTEINS; ORGANISMS, GENETICALLY MODIFIED; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 82855177881     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2011.044115     Document Type: Article

References (39)

1. Yuan JS, Kousis PC, Suliman S, Visan I, Guidos CJ. Functions of notch signaling in the immune system: consensus and controversies. Annu Rev Immunol. 2010;23:343-365.
2. Ohishi K, Katayama N, Shiku H, Varnum-Finney B, Bernstein ID. Notch signalling in hematopoiesis. Semin Cell Dev Biol. 2003; 14(2):143-50.
3. Jarriault S, Brou C, Logeat F, Schroeter EH, Kopan R, Israel A. Signalling downstream of activated mammalian Notch. Nature. 1995;377(6547):355-8.
4. Ellisen LW, Bird J, West DC, Soreng AL, Reynolds TC, Smith SD, Sklar J. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell. 1991;66:649-61.
5. Milner LA, Bigas A, Kopan R, Brashem-Stein C, Bernstein ID, Martin DI. Inhibition of granulocytic differentiation by mNotch1. PNAS. 1996;93(23):13014-9.
6. Schroeder T, Kohlhof H, Rieber N, Just U. Notch signaling induces multilineage myeloid differentiation and up-regulates PU.1 expression. J Immunol. 2003;170(11): 5538-48.
7. Stier S, Cheng T, Dombkowski D, Carlesso N, Scadden DT. Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome. Blood. 2002;99(7):2369-78.
8. Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 2005;19(19):2331-42.
9. Cheng P, Nefedova Y, Miele L, Osborne BA, Gabrilovich D. Notch signaling is necessary but not sufficient for differentiation of dendritic cells. Blood. 2003;102(12):3980-8.
10. Mazzone M, Selfors LM, Albeck J, Overholtzer M, Sale S, Carroll DL et al. Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells. PNAS. 2010;16(11):5012-7.
11. Kim YW, Koo BK, Jeong HW, Yoon MJ, Song R, Shin J, et al. Defective Notch activation in microenvironment leads to myeloproliferative disease. Blood. 2008; 112(12):4628-38.
12. Haffter P, Nüsslein-Volhard C. Large scale genetics in a small vertebrate, the zebrafish. Int J Dev Biol. 1996;40(1):221-7.
13. Jülich D, Hwee Lim C, Round J, Nicolaije C, Schroeder J, Davies A, et al. Beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation. Tübingen 2000 Screen Consortium. Dev Biol. 2005;286:391-404.
14. Holley SA, Jülich D, Rauch GJ, Geisler R, Nüsslein-Volhard CC. her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis. Development. 2002;129(5):1175-83.
15. Gray M, Moens CB, Amacher SL, Eisen JS, Beattie CE. Zebrafish deadly seven functions in neurogenesis. Dev Biol. 2001; 237(2):306-23
16. Hsu K, Traver D, Kutok JL, Hagen A, Liu TX, Paw BH, Rhodes J, Berman JN, Zon LI, Kanki JP, Look AT. The pu.1 promoter drives myeloid gene expression in zebrafish. Blood. 2004;104(5):1291-7.
17. Renshaw SA, Loynes CA, Trushell DM, Elworthy S, Ingham PW, Whyte MK. A transgenic zebrafish model of neutrophilic inflammation. Blood. 2006;108(13):3976-8.
18. Gray C, Loynes CA, Whyte MK, Crossman DC, Renshaw SA, Chico TJ. Simultaneous intravital imaging of macrophage and neutrophil behaviour during inflammation using a novel transgenic zebrafish. Thromb Haemost. 2011;105(5):811-9.
19. Thisse C, Thisse B. High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat Protoc. 2008;3(1):59-69.
20. Traver D, Paw BH, Poss KD, Penberthy WT, Lin S, Zon LI. Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol. 2003;4(12):1238-46.
21. Moss LD, Monette MM, Jaso-Friedmann L, Leary JH 3rd, Dougan ST, Krunkosky T, et al. Identification of phagocytic cells, NKlike cytotoxic cell activity and the production of cellular exudates in the coelomic cavity of adult zebrafish. Dev Comp Immunol. 2009;33(10):1077-87.
22. Lam SH, Chua HL, Gong Z, Wen Z, Lam TJ, Sin YM. Morphologic transformation of the thymus in developing zebrafish. Dev Dyn. 2002;225(1):87-94.
23. Lieschke GJ, Oates AC, Crowhurst MO, Ward AC, Layton JE. Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish. Blood. 2001;98(10):3087-96.
24. Brown SB, Tucker CS, Ford C, Lee Y, Dunbar DR, Mullins JJ. Class III antiarrhythmic methanesulfonanilides inhibit leukocyte recruitment in zebrafish. J Leukoc Biol. 2007;82(1):79-84.
25. Redd MJ, Kelly G, Dunn G, Way M, Martin P. Imaging macrophage chemotaxis in vivo: studies of microtubule function in zebrafish wound inflammation. Cell Motil Cytoskeleton. 2006;63(7):415-22
26. Geling A, Steiner H, Willem M, Bally-Cuif L, Haass C. A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish. EMBO Rep. 2002.3(7):688-94.
27. Monsalve E, Ruiz-García A, Baladrón V, Ruiz-Hidalgo MJ, Sánchez-Solana B, Rivero S, et al. Notch1 upregulates LPS-induced macrophage activation by increasing NFkappaB activity. Eur J Immunol. 2009.39 (9):2556-70.
28. Visan I, Tan JB, Yuan JS, Harper JA, Koch U, Guidos CJ. Regulation of T lymphopoiesis by Notch1 and Lunatic fringe-mediated competition for intrathymic niches. Nat Immunol. 2006;7(6):634-43.
29. Outtz HH, Wu JK, Wang X, Kitajewski J. Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages. J Immunol. 2010;185(7):4363-73.
30. Taylor JS, Braasch I, Frickey T, Meyer A, Van de Peer Y. Genome duplication, a trait shared by 22000 species of ray-finned fish. Genome Res. 2003;13(3):382-90.
31. Schwanbeck R, Schroeder T, Henning K, Kohlhof H, Rieber N, Erfurth ML, Just U. Notch signaling in embryonic and adult myelopoiesis. Cells Tissues Organs. 2008; 188(1-2):91-102.
32. Coccia EM, Stellacci E, Valtieri M, Masella B, Feccia T, Marziali G, Hiscott J, Testa U, Peschle C, Battistini A. Ectopic expression of interferon regulatory factor-1 potentiates granulocytic differentiation. Biochem J. 2001;360(2):285-94.
33. Manzella L, Conte E, Cocchiaro G, Guarniera E, Sciacca B, Bonaiuto C, Stagno F, Messina A. Role of interferon regulatory factor 1 in monocyte/macrophage differentiation. Eur J Immunol. 1999; 29(9):3009-16.
34. Bellon T, Perrotti D, Calabretta B. Granulocytic differentiation of normal hematopoietic precursor cells induced by transcription factor PU.1 correlates with negative regulation of the c-myb promoter. Blood. 1997;90(5):1828-39.
35. Bertrand JY, Cisson JL, Stachura DL, Traver D. Notch signaling distinguishes 2 waves of definitive hematopoiesis in the zebrafish embryo. Blood. 2010;115(14):2777-8.
36. Maillard I, Koch U, Dumortier A, Shestova O, Xu L. Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells. Cell Stem Cell. 2008;10(4):356-66.
37. Radtke F, Fasnacht N, Macdonald HR. Notch signaling in the immune system. Immunity. 2010;29(1):14-27.
38. Maeda T, Merghoub T, Hobbs RM, Dong L, Maeda M, Zakrzewski J, et al. Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF. Science. 2007;11(5826):860-6.
39. Poirault-Chassac S, Six E, Catelain C, Lavergne M, Villeval JL, Vainchenker W, et al. Notch/Delta4 signaling inhibits human megakaryocytic terminal differentiation. Blood. 2010;116(25):5670-8.